PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1xzzA_

Fold library id	PDB Header	Molecule	Title
c1xzzA_	PDB header: membrane protein	Chain: A: PDB Molecule: inositol 1,4,5-trisphosphate receptor type 1;	PDBTitle: crystal structure of the ligand binding suppressor domain2 of type 1 inositol 1,4,5-trisphosphate receptor

Links to external resources
Added to library: Tue Mar 16 12:26:56 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S F L H I G D I C S L Y A E G S T N G F I S T L G L V D D R C V V Q P E A G D L N N P P K K F R D C L F K L C P M N R Y S A Q K Q F W K A S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
B T T
S S S
S
S S
B
G G G
S S S
S
G G G G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence T T D A V L L N K L H H A A D L E K K Q N E T E N R K L L G T V I Q Y G N V I Q L L H L K S N K Y L T V N K R L P A L L E K N A M R V T L D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
B
B T T
T T T T
S S S T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence E A G N E G S W F Y I Q P F Y K L R S I G D S V V I G D K V V L N P V N A G Q P L H A S S H Q L V D N P G C N E V N S V N C N T S W K I V L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
G G G
S S T T S
T T S B
B T T
S S S
S
S S S S S
S S

. . . . . .

Sequence F L E H H H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	F	L	H	I	G	D	I	C	S	L	Y	A	E	G	S	T	N	G	F	I	S	T	L	G	L	V	D	D	R	C	V	V	Q	P	E	A	G	D	L	N	N	P	P	K	K	F	R	D	C	L	F	K	L	C	P	M	N	R	Y	S	A	Q	K	Q	F	W	K	A	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		B		B	T	T									S	S	S							S		S	S			B					G	G	G			S	S	S			S		G	G	G	G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	T	T	D	A	V	L	L	N	K	L	H	H	A	A	D	L	E	K	K	Q	N	E	T	E	N	R	K	L	L	G	T	V	I	Q	Y	G	N	V	I	Q	L	L	H	L	K	S	N	K	Y	L	T	V	N	K	R	L	P	A	L	L	E	K	N	A	M	R	V	T	L	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																												T	T	T		B		B	T	T								T	T	T	T												S	S	S	T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	E	A	G	N	E	G	S	W	F	Y	I	Q	P	F	Y	K	L	R	S	I	G	D	S	V	V	I	G	D	K	V	V	L	N	P	V	N	A	G	Q	P	L	H	A	S	S	H	Q	L	V	D	N	P	G	C	N	E	V	N	S	V	N	C	N	T	S	W	K	I	V	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S			G	G	G							S	S	T	T	S		T	T	S	B		B	T	T								S	S	S		S										S	S	S	S	S							S	S
	.	.	.	.	.	.
Sequence	F	L	E	H	H	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T