PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1wxrA_

Fold library id	PDB Header	Molecule	Title
c1wxrA_	PDB header: hydrolase	Chain: A: PDB Molecule: haemoglobin protease;	PDBTitle: crystal structure of heme binding protein, an2 autotransporter hemoglobine protease from pathogenic3 escherichia coli

Links to external resources
Added to library: Tue Mar 16 13:05:30 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G T V N N E L G Y Q L F R D F A E N K G M F R P G A T N I A I Y N K Q G E F V G T L D K A A M P D F S A V D S E I G V A T L I N P Q Y I A S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T T
G G G S T T
S
T T S
S S
T T B
T T T
T T B

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V K H N G G Y T N V S F G D G E N R Y N I V D R N N A P S L D F H A P R L D K L V T E V A P T A V T A Q G A V A G A Y L D K E R Y P V F Y R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S
T T S
B
S S S S
B
S S
S S
B
S S
S
T T G G G
T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L G S G T Q Y I K D S N G Q L T K M G G A Y S W L T G G T V G S L S S Y Q N G E M I S T S S G L V F D Y K L N G A M P I Y G E A G D S G S P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
T T S S
T T T T
T T
T T
S S B
B
T T
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence L F A F D T V Q N K W V L V G V L T A G N G A G G R G N N W A V I P L D F I G Q K F N E D N D A P V T F R T S E G G A L E W S F N S S T G A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T S S T T
S
T T B
G G G
S
T T T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence G A L T Q G T T T Y A M H G Q Q G N D L N A G K N L I F Q G Q N G Q I N L K D S V S Q G A G S L T F R D N Y T V T T S N G S T W T G A G I V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
B T T B G G G
B S T T S S
T T
S S
S S
S S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence V D N G V S V N W Q V N G V K G D N L H K I G E G T L T V Q G T G I N E G G L K V G D G K V V L N Q Q A D N K G Q V Q A F S S V N I A S G R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T
S S S
B S B
S
S S
B
T T S
B S
S
S S

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence P T V V L T D E R Q V N P D T V S W G Y R G G T L D V N G N S L T F H Q L K A A D Y G A V L A N N V D K R A T I T L D Y A L R A D K V A L N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T S S
G G G
T T
T T
S
S T T
S S S
G G G

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence G W S E S G K G T A G N L Y K Y N N P Y T N T T D Y F I L K Q S T Y G Y F P T D Q S S N A T W E F V G H S Q G D A Q K L V A D R F N T A G Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
B
T T
T T T T
S S B
S S S
S S
S
T T S

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence L F H G Q L K G N L N V D N R L P E G V T G A L V M D G A A D I S G T F T Q E N G R L T L Q G H P V I H A Y N T Q S V A D K L A A S G D H S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T
S S S
T T

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence V L T Q P T S F S Q E D W E N R S F T F D R L S L K N T D F G L G R N A T L N T T I Q A D N S S V T L G D S R V F I D K N D G Q G T A F T L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
S S
S
S
T T S
S
S T T T T S S S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence E E G T S V A T K D A D K S V F N G T V N L D N Q S V L N I N D I F N G G I Q A N N S T V N I S S D S A V L G N S T L T S T A L N L N K G A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S G G G S
S S
S S
S S
S S
T T

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence N A L A S Q S F V S D G P V N I S D A T L S L N S R P D E V S H T L L P V Y D Y A G S W N L K G D D A R L N V G P Y S M L S G N I N V Q D K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S S S S S
T T
S S B
S T T
S S S S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence G T V T L G G E G E L S P D L T L Q N Q M L Y S L F N G Y R N I W S G S L N A P D A T V S M T D T Q W S M N G N S T A G N M K L N R T I V G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
B
S
T T T
S
S
S
S

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence F N G F T T L T T D N L D A V Q S A F V M R T K A D K L V I N K S A T G H D N S I W V N F L K K P S N K D T L D I P L V S A P E A T A D N L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
S S S
T T S
G G G

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020 . . . . . . . . . 1030 . . . . .

Sequence F R A S T R V V G F S D V T P I L S V R K E D G K K E W V L D G Y Q V A R A A A T F M H I S Y N N F I T E V N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S S S S
T T
S G G G

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	T	V	N	N	E	L	G	Y	Q	L	F	R	D	F	A	E	N	K	G	M	F	R	P	G	A	T	N	I	A	I	Y	N	K	Q	G	E	F	V	G	T	L	D	K	A	A	M	P	D	F	S	A	V	D	S	E	I	G	V	A	T	L	I	N	P	Q	Y	I	A	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S	S		T								T	T		G	G	G	S	T	T			S						T	T	S								S	S						T	T	B		T	T	T								T	T				B
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	K	H	N	G	G	Y	T	N	V	S	F	G	D	G	E	N	R	Y	N	I	V	D	R	N	N	A	P	S	L	D	F	H	A	P	R	L	D	K	L	V	T	E	V	A	P	T	A	V	T	A	Q	G	A	V	A	G	A	Y	L	D	K	E	R	Y	P	V	F	Y	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T			S							T	T	S											B		S	S	S	S		B					S	S				S	S					B		S	S		S		T	T	G	G	G		T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	G	S	G	T	Q	Y	I	K	D	S	N	G	Q	L	T	K	M	G	G	A	Y	S	W	L	T	G	G	T	V	G	S	L	S	S	Y	Q	N	G	E	M	I	S	T	S	S	G	L	V	F	D	Y	K	L	N	G	A	M	P	I	Y	G	E	A	G	D	S	G	S	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S							T	T									T	T	S	S													T	T	T	T						T	T		T	T							S	S	B		B			T	T		T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	L	F	A	F	D	T	V	Q	N	K	W	V	L	V	G	V	L	T	A	G	N	G	A	G	G	R	G	N	N	W	A	V	I	P	L	D	F	I	G	Q	K	F	N	E	D	N	D	A	P	V	T	F	R	T	S	E	G	G	A	L	E	W	S	F	N	S	S	T	G	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	T	T												S	S	T	T		S																		T	T	B								G	G	G		S								T	T	T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	G	A	L	T	Q	G	T	T	T	Y	A	M	H	G	Q	Q	G	N	D	L	N	A	G	K	N	L	I	F	Q	G	Q	N	G	Q	I	N	L	K	D	S	V	S	Q	G	A	G	S	L	T	F	R	D	N	Y	T	V	T	T	S	N	G	S	T	W	T	G	A	G	I	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T									B	T	T	B	G	G	G			B					S	T	T						S	S					T	T						S	S							S	S						S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	V	D	N	G	V	S	V	N	W	Q	V	N	G	V	K	G	D	N	L	H	K	I	G	E	G	T	L	T	V	Q	G	T	G	I	N	E	G	G	L	K	V	G	D	G	K	V	V	L	N	Q	Q	A	D	N	K	G	Q	V	Q	A	F	S	S	V	N	I	A	S	G	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T											T	T							S	S	S							B	S	B			S						S	S							B			T	T	S			B	S		S						S	S
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	P	T	V	V	L	T	D	E	R	Q	V	N	P	D	T	V	S	W	G	Y	R	G	G	T	L	D	V	N	G	N	S	L	T	F	H	Q	L	K	A	A	D	Y	G	A	V	L	A	N	N	V	D	K	R	A	T	I	T	L	D	Y	A	L	R	A	D	K	V	A	L	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S	T	T	S	S		G	G	G					T	T							T	T						S						S	T	T							S	S	S												G	G	G
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	G	W	S	E	S	G	K	G	T	A	G	N	L	Y	K	Y	N	N	P	Y	T	N	T	T	D	Y	F	I	L	K	Q	S	T	Y	G	Y	F	P	T	D	Q	S	S	N	A	T	W	E	F	V	G	H	S	Q	G	D	A	Q	K	L	V	A	D	R	F	N	T	A	G	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T		B			T	T								T	T	T	T									S	S	B						S	S	S				S	S						S														T	T	S
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	L	F	H	G	Q	L	K	G	N	L	N	V	D	N	R	L	P	E	G	V	T	G	A	L	V	M	D	G	A	A	D	I	S	G	T	F	T	Q	E	N	G	R	L	T	L	Q	G	H	P	V	I	H	A	Y	N	T	Q	S	V	A	D	K	L	A	A	S	G	D	H	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S					S									T	T									S												S	S																									T	T
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	V	L	T	Q	P	T	S	F	S	Q	E	D	W	E	N	R	S	F	T	F	D	R	L	S	L	K	N	T	D	F	G	L	G	R	N	A	T	L	N	T	T	I	Q	A	D	N	S	S	V	T	L	G	D	S	R	V	F	I	D	K	N	D	G	Q	G	T	A	F	T	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S	S			S	S		S																S							T	T											S						S		S						T	T	T	T	S	S	S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	E	E	G	T	S	V	A	T	K	D	A	D	K	S	V	F	N	G	T	V	N	L	D	N	Q	S	V	L	N	I	N	D	I	F	N	G	G	I	Q	A	N	N	S	T	V	N	I	S	S	D	S	A	V	L	G	N	S	T	L	T	S	T	A	L	N	L	N	K	G	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S	G	G	G	S											S	S							S										S								S	S					S					S							T	T
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	N	A	L	A	S	Q	S	F	V	S	D	G	P	V	N	I	S	D	A	T	L	S	L	N	S	R	P	D	E	V	S	H	T	L	L	P	V	Y	D	Y	A	G	S	W	N	L	K	G	D	D	A	R	L	N	V	G	P	Y	S	M	L	S	G	N	I	N	V	Q	D	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S					S	S						S	S					S	S		T	T				S	S	B														S	T	T							S	S											S	S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	G	T	V	T	L	G	G	E	G	E	L	S	P	D	L	T	L	Q	N	Q	M	L	Y	S	L	F	N	G	Y	R	N	I	W	S	G	S	L	N	A	P	D	A	T	V	S	M	T	D	T	Q	W	S	M	N	G	N	S	T	A	G	N	M	K	L	N	R	T	I	V	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S			B		S													T	T	T		S																		S							S											S
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	F	N	G	F	T	T	L	T	T	D	N	L	D	A	V	Q	S	A	F	V	M	R	T	K	A	D	K	L	V	I	N	K	S	A	T	G	H	D	N	S	I	W	V	N	F	L	K	K	P	S	N	K	D	T	L	D	I	P	L	V	S	A	P	E	A	T	A	D	N	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																S																														S	S				S	S	S											T	T	S		G	G	G
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.
Sequence	F	R	A	S	T	R	V	V	G	F	S	D	V	T	P	I	L	S	V	R	K	E	D	G	K	K	E	W	V	L	D	G	Y	Q	V	A	R	A	A	A	T	F	M	H	I	S	Y	N	N	F	I	T	E	V	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S			S	S	S	S											T	T																	S	G	G	G