PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1uupA_

Fold library id	PDB Header	Molecule	Title
c1uupA_	PDB header: toxin	Chain: A: PDB Molecule: exotoxin type a;	PDBTitle: crystal structure of a dimeric form of streptococcal2 pyrogenic exotoxin a (spea1).

Links to external resources
Added to library: Tue Mar 16 12:51:28 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Q Q D P D P S Q L H R S S L V K N L Q N I Y F L Y E G D P V T H E N V K S V D Q L L S H D L I Y N V S G P N Y D K L K T E L K N Q E M A T L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G S
G G G
S S T S
B
S S T T
B T T B S
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence F K D K N V D I Y G V E Y Y H L C Y L C E N A E R S A C I Y G G V T N H E G N H L E I P K K I V V K V S I D G I Q S L S F D I E T N K K M V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
B
T T
S S S
S S
T T
T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T A Q E L D Y K V R K Y L T D N K Q L Y T N G P S K Y E T G Y I K F I P K N K E S F W F D F F P E P E F T Q S K Y L M I Y K D N E T L D S N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
S
S S S
S S
S S
G G G G T T
T T

. . . . . . . . . 220 .

Sequence T S Q I E V Y L T T K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Q	Q	D	P	D	P	S	Q	L	H	R	S	S	L	V	K	N	L	Q	N	I	Y	F	L	Y	E	G	D	P	V	T	H	E	N	V	K	S	V	D	Q	L	L	S	H	D	L	I	Y	N	V	S	G	P	N	Y	D	K	L	K	T	E	L	K	N	Q	E	M	A	T	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						G	G	G	S			G	G	G		S	S	T									S												B		S	S	T	T								B	T	T	B	S							S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	F	K	D	K	N	V	D	I	Y	G	V	E	Y	Y	H	L	C	Y	L	C	E	N	A	E	R	S	A	C	I	Y	G	G	V	T	N	H	E	G	N	H	L	E	I	P	K	K	I	V	V	K	V	S	I	D	G	I	Q	S	L	S	F	D	I	E	T	N	K	K	M	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	S									B		T	T				S	S	S		S	S												T	T																T	T													S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	A	Q	E	L	D	Y	K	V	R	K	Y	L	T	D	N	K	Q	L	Y	T	N	G	P	S	K	Y	E	T	G	Y	I	K	F	I	P	K	N	K	E	S	F	W	F	D	F	F	P	E	P	E	F	T	Q	S	K	Y	L	M	I	Y	K	D	N	E	T	L	D	S	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																			S			S	S			S											S	S	S							S	S			S	S							G	G	G	G	T	T						T	T
	.	.	.	.	.	.	.	.	.	220	.
Sequence	T	S	Q	I	E	V	Y	L	T	T	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T