PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1tfzA_

Fold library id	PDB Header	Molecule	Title
c1tfzA_	PDB header: oxidoreductase	Chain: A: PDB Molecule: 4-hydroxyphenylpyruvate dioxygenase;	PDBTitle: structural basis for herbicidal inhibitor selectivity2 revealed by comparison of crystal structures of plant and3 mammalian 4-hydroxyphenylpyruvate dioxygenases

Links to external resources
Added to library: Tue Mar 16 13:14:52 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence N P K S D K F K V K R F H H I E F W C G D A T N V A R R F S W G L G M R F S A K S D L S T G N M V H A S Y L L T S G D L R F L F T A P Y S P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
S
T
S G G G T
S S T T
G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence S L S A G E I K P T T T A S I P S F D H G S C R S F F S S H G L G V R A V A I E V E D A E S A F S I S V A N G A I P S S P P I V L N E A V T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G T T
G G G
S S T T
S S
T T
T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I A E V K L Y G D V V L R Y V S Y K E F L P G F E R V E D A S S F P L D Y G I R R L D H A V G N V P E L G P A L T Y V A G F T G F H Q F A S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S T T
G G G S
S
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence G L N S A V L A S N D E M V L L P I N E P V H G K S Q I Q T Y L E H N E G A G L Q H L A L M S E D I F R T L R E M R K R S S I G G F D F M P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S
T S
S
G G G T S
B

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence S P P P T Y Y Q N L K K R V G D V L S D D Q I K E C E E L G I L V D R D D Q G T L L Q I F T K P L G D R P T I F I E I I Q R V G C M Q S G G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T T S
T
S S B S
S S S S S
T T

. . . . . . . . . 360 . . . .

Sequence C G G F G K G N F S E L F K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	N	P	K	S	D	K	F	K	V	K	R	F	H	H	I	E	F	W	C	G	D	A	T	N	V	A	R	R	F	S	W	G	L	G	M	R	F	S	A	K	S	D	L	S	T	G	N	M	V	H	A	S	Y	L	L	T	S	G	D	L	R	F	L	F	T	A	P	Y	S	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S													S														T								S	G	G	G	T		S	S									T	T											G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	S	L	S	A	G	E	I	K	P	T	T	T	A	S	I	P	S	F	D	H	G	S	C	R	S	F	F	S	S	H	G	L	G	V	R	A	V	A	I	E	V	E	D	A	E	S	A	F	S	I	S	V	A	N	G	A	I	P	S	S	P	P	I	V	L	N	E	A	V	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	G	T	T			G	G	G				S	S	T	T															S										S												T	T											T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	A	E	V	K	L	Y	G	D	V	V	L	R	Y	V	S	Y	K	E	F	L	P	G	F	E	R	V	E	D	A	S	S	F	P	L	D	Y	G	I	R	R	L	D	H	A	V	G	N	V	P	E	L	G	P	A	L	T	Y	V	A	G	F	T	G	F	H	Q	F	A	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T												S	T	T						G	G	G	S						S												S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	G	L	N	S	A	V	L	A	S	N	D	E	M	V	L	L	P	I	N	E	P	V	H	G	K	S	Q	I	Q	T	Y	L	E	H	N	E	G	A	G	L	Q	H	L	A	L	M	S	E	D	I	F	R	T	L	R	E	M	R	K	R	S	S	I	G	G	F	D	F	M	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	S		S																						T	S											S													G	G	G	T	S			B
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	S	P	P	P	T	Y	Y	Q	N	L	K	K	R	V	G	D	V	L	S	D	D	Q	I	K	E	C	E	E	L	G	I	L	V	D	R	D	D	Q	G	T	L	L	Q	I	F	T	K	P	L	G	D	R	P	T	I	F	I	E	I	I	Q	R	V	G	C	M	Q	S	G	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S	T	T	T	S												T							S	S								B	S		S	S	S	S	S																T	T
	.	.	.	.	.	.	.	.	.	360	.	.	.	.
Sequence	C	G	G	F	G	K	G	N	F	S	E	L	F	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T		S	S