PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1rkcA_

Fold library id	PDB Header	Molecule	Title
c1rkcA_	PDB header: cell adhesion, structural protein	Chain: A: PDB Molecule: vinculin;	PDBTitle: human vinculin head (1-258) in complex with talin's2 vinculin binding site 3 (residues 1944-1969)

Links to external resources
Added to library: Tue Mar 16 13:03:05 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M P V F H T R T I E S I L E P V A Q Q I S H L V I M H E E G E V D G K A I P D L T A P V A A V Q A A V S N L V R V G K E T V Q T T E D Q I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B T T T T T T
S G G G T T T T T S T T T S T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence K R D M P P A F I K V E N A C T K L V Q A A Q M L Q S D P Y S V P A R D Y L I D G S R G I L S G T S D L L L T F D E A E V R K I I R V C K G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S T T G G G T S S S
T T
T T G G G S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I L E Y L T V A E V V E T M E D L V T Y T K N L G P G M T K M A K M I D E R Q Q E L T H Q E H R V M L V N S M N T V K E L L P V L I S A M K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G
S T T B S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . .

Sequence I F V T T K N S K N Q G I E E A L K N R N F T V E K M S A E I N E I I R V L Q L T S W D E D A W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S S
S
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	P	V	F	H	T	R	T	I	E	S	I	L	E	P	V	A	Q	Q	I	S	H	L	V	I	M	H	E	E	G	E	V	D	G	K	A	I	P	D	L	T	A	P	V	A	A	V	Q	A	A	V	S	N	L	V	R	V	G	K	E	T	V	Q	T	T	E	D	Q	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						B								T												T	T	T	T	T							S	G	G	G	T	T	T	T	T	S	T	T	T	S	T	T												S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	K	R	D	M	P	P	A	F	I	K	V	E	N	A	C	T	K	L	V	Q	A	A	Q	M	L	Q	S	D	P	Y	S	V	P	A	R	D	Y	L	I	D	G	S	R	G	I	L	S	G	T	S	D	L	L	L	T	F	D	E	A	E	V	R	K	I	I	R	V	C	K	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T										T					S	T	T	G	G	G	T	S	S	S		T	T		T	T	G	G	G	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	L	E	Y	L	T	V	A	E	V	V	E	T	M	E	D	L	V	T	Y	T	K	N	L	G	P	G	M	T	K	M	A	K	M	I	D	E	R	Q	Q	E	L	T	H	Q	E	H	R	V	M	L	V	N	S	M	N	T	V	K	E	L	L	P	V	L	I	S	A	M	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								G	G	G			S																											T	T	B	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.
Sequence	I	F	V	T	T	K	N	S	K	N	Q	G	I	E	E	A	L	K	N	R	N	F	T	V	E	K	M	S	A	E	I	N	E	I	I	R	V	L	Q	L	T	S	W	D	E	D	A	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	S	S	S																																S			S	S