PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1piwA_

Fold library id	PDB Header	Molecule	Title
c1piwA_	PDB header: oxidoreductase	Chain: A: PDB Molecule: hypothetical zinc-type alcohol dehydrogenase-	PDBTitle: apo and holo structures of an nadp(h)-dependent cinnamyl2 alcohol dehydrogenase from saccharomyces cerevisiae

Links to external resources
Added to library: Tue Mar 16 13:33:13 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M S Y P E K F E G I A I Q S H E D W K N P K K T K Y D P K P F Y D H D I D I K I E A C G V C G S D I H C A A G H W G N M K M P L V V G H E I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T
S S S T T S
T T
T T T T S
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V G K V V K L G P K S N S G L K V G Q R V G V G A Q V F S C L E C D R C K N D N E P Y C T K F V T T Y S Q P Y E D G Y V S Q G G Y A N Y V R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S
T T
S
S
S T T
G G G
T T
S S S
B
T T S
B
S S B S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V H E H F V V P I P E N I P S H L A A P L L C G G L T V Y S P L V R N G C G P G K K V G I V G L G G I G S M G T L I S K A M G A E T Y V I S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G G
T T S
G G G G T T T
S T T
S T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence R S S R K R E D A M K M G A D H Y I A T L E E G D W G E K Y F D T F D L I V V C A S S L T D I D F N I M P K A M K V G G R I V S I S I P E Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S T T T
S G G G T S
S
S
S
S T T
T T T G G G G
S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence H E M L S L K P Y G L K A V S I S Y S A L G S I K E L N Q L L K L V S E K D I K I W V E T L P V G E A G V H E A F E R M E K G D V R Y R F T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G
S S
T T
S S T
S S

. . . . . . . . . 360

Sequence L V G Y D K E F S D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	S	Y	P	E	K	F	E	G	I	A	I	Q	S	H	E	D	W	K	N	P	K	K	T	K	Y	D	P	K	P	F	Y	D	H	D	I	D	I	K	I	E	A	C	G	V	C	G	S	D	I	H	C	A	A	G	H	W	G	N	M	K	M	P	L	V	V	G	H	E	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	T										S	S	S	T	T	S													T	T																				T	T	T	T	S				S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	G	K	V	V	K	L	G	P	K	S	N	S	G	L	K	V	G	Q	R	V	G	V	G	A	Q	V	F	S	C	L	E	C	D	R	C	K	N	D	N	E	P	Y	C	T	K	F	V	T	T	Y	S	Q	P	Y	E	D	G	Y	V	S	Q	G	G	Y	A	N	Y	V	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T			S	S			T	T							S						S		S					T	T		G	G	G		T	T				S	S	S		B		T	T	S		B				S	S	B	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	H	E	H	F	V	V	P	I	P	E	N	I	P	S	H	L	A	A	P	L	L	C	G	G	L	T	V	Y	S	P	L	V	R	N	G	C	G	P	G	K	K	V	G	I	V	G	L	G	G	I	G	S	M	G	T	L	I	S	K	A	M	G	A	E	T	Y	V	I	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			G	G	G						T	T	S						G	G	G	G	T												T	T		S	T	T									S														T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	R	S	S	R	K	R	E	D	A	M	K	M	G	A	D	H	Y	I	A	T	L	E	E	G	D	W	G	E	K	Y	F	D	T	F	D	L	I	V	V	C	A	S	S	L	T	D	I	D	F	N	I	M	P	K	A	M	K	V	G	G	R	I	V	S	I	S	I	P	E	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S	S	S	T	T								T		S					G	G	G	T	S						S		S										S		S	T	T			T	T	T	G	G	G	G															S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	H	E	M	L	S	L	K	P	Y	G	L	K	A	V	S	I	S	Y	S	A	L	G	S	I	K	E	L	N	Q	L	L	K	L	V	S	E	K	D	I	K	I	W	V	E	T	L	P	V	G	E	A	G	V	H	E	A	F	E	R	M	E	K	G	D	V	R	Y	R	F	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S							G	G	G		S	S																								T	T										S	S														T			S	S
	.	.	.	.	.	.	.	.	.	360
Sequence	L	V	G	Y	D	K	E	F	S	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)