PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1p9mC_

Fold library id	PDB Header	Molecule	Title
c1p9mC_	PDB header: signaling protein/cytokine	Chain: C: PDB Molecule: interleukin-6 receptor alpha chain;	PDBTitle: crystal structure of the hexameric human il-6/il-6 alpha2 receptor/gp130 complex

Links to external resources
Added to library: Tue Mar 16 12:34:23 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence E E P Q L S C F R K S P L S N V V C E W G P R S T P S L T T K A V L L V R K F Q N S P A E D F Q E P C Q Y S Q E S Q K F S C Q L A V P E G D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B S S S S S
B
S S
S S
S S S S
T T T T
B
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence S S F Y I V S M C V A S S V G S K F S K T Q T F Q G C G I L Q P D P P A N I T V T A V A R N P R W L S V T W Q D P H S W N S S F Y R L R F E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T S S B
T T
T T
T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 .

Sequence L R Y R A E R S K T F T T W M V K D L Q H H C V I H D A W S G L R H V V Q L R A Q E E F G Q G E W S E W S P E A M G T P W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S S
S
S S
S S
T T T B S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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All images and data generated by Phyre2 are free to use in any publication with acknowledgement
Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	E	E	P	Q	L	S	C	F	R	K	S	P	L	S	N	V	V	C	E	W	G	P	R	S	T	P	S	L	T	T	K	A	V	L	L	V	R	K	F	Q	N	S	P	A	E	D	F	Q	E	P	C	Q	Y	S	Q	E	S	Q	K	F	S	C	Q	L	A	V	P	E	G	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									B	S	S	S	S	S		B							S	S				S	S											S	S	S	S												T	T	T	T						B				T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	S	S	F	Y	I	V	S	M	C	V	A	S	S	V	G	S	K	F	S	K	T	Q	T	F	Q	G	C	G	I	L	Q	P	D	P	P	A	N	I	T	V	T	A	V	A	R	N	P	R	W	L	S	V	T	W	Q	D	P	H	S	W	N	S	S	F	Y	R	L	R	F	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S	S	S												T	T	S	S	B														T	T													T	T				T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.
Sequence	L	R	Y	R	A	E	R	S	K	T	F	T	T	W	M	V	K	D	L	Q	H	H	C	V	I	H	D	A	W	S	G	L	R	H	V	V	Q	L	R	A	Q	E	E	F	G	Q	G	E	W	S	E	W	S	P	E	A	M	G	T	P	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T										S	S	S		S					S	S			S	S												T	T	T	B	S