PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1nmqB_

Fold library id	PDB Header	Molecule	Title
c1nmqB_	PDB header: apoptosis, hydrolase	Chain: B: PDB Molecule: caspase-3;	PDBTitle: extendend tethering: in situ assembly of inhibitors

Links to external resources
Added to library: Tue Mar 16 14:39:05 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence D N S Y K M D Y P E M G L C I I I N N K N F H K S T G M T S R S G T D V D A A N L R E T F R N L K Y E V R N K N D L T R E E I V E L M R D V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
S S
G G G
T T T T
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence S K E D H S K R S S F V C V L L S H G E E G I I F G T N G P V D L K K I T N F F R G D R C R S L T G K P K L F I I Q A C R G T E L D C G I E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
T T S
T T T T T T S T T T
T T T T T S
S
S B
B

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence T D D D C H K I P V D A D F L Y A Y S T A P G Y Y S W R N S K D G S W F I Q S L C A M L K Q Y A D K L E F M H I L T R V N R K V A T E F E S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T S S
T T B
T T T T T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . .

Sequence F S F D A T F H A K K Q I P C I V S M L T K E L Y F Y H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S G G G S S
B
S S B
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	D	N	S	Y	K	M	D	Y	P	E	M	G	L	C	I	I	I	N	N	K	N	F	H	K	S	T	G	M	T	S	R	S	G	T	D	V	D	A	A	N	L	R	E	T	F	R	N	L	K	Y	E	V	R	N	K	N	D	L	T	R	E	E	I	V	E	L	M	R	D	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			B					S	S															G	G	G						T	T															T	T								S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	S	K	E	D	H	S	K	R	S	S	F	V	C	V	L	L	S	H	G	E	E	G	I	I	F	G	T	N	G	P	V	D	L	K	K	I	T	N	F	F	R	G	D	R	C	R	S	L	T	G	K	P	K	L	F	I	I	Q	A	C	R	G	T	E	L	D	C	G	I	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	S			T	T										S				T	T					T	T											T	T	S	T	T	T		T	T	T	T	T	S								S				S	B		B
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	T	D	D	D	C	H	K	I	P	V	D	A	D	F	L	Y	A	Y	S	T	A	P	G	Y	Y	S	W	R	N	S	K	D	G	S	W	F	I	Q	S	L	C	A	M	L	K	Q	Y	A	D	K	L	E	F	M	H	I	L	T	R	V	N	R	K	V	A	T	E	F	E	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	T	T						S	S		T	T	B						T	T	T																T	T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Sequence	F	S	F	D	A	T	F	H	A	K	K	Q	I	P	C	I	V	S	M	L	T	K	E	L	Y	F	Y	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S	G	G	G	S	S		B										S	S	B			S