PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1kcwA_

Fold library id	PDB Header	Molecule	Title
c1kcwA_	PDB header: oxidoreductase	Chain: A: PDB Molecule: ceruloplasmin;	PDBTitle: x-ray crystal structure of human ceruloplasmin at 3.02 angstroms

Links to external resources
Added to library: Tue Mar 16 13:06:12 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence K E K H Y Y I G I I E T T W D Y A S D H G E K K L I S V D T E H S N I Y L Q N G P D R I G R L Y K K A L Y L Q Y T D E T F R T T I E K P V W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S S
T T T T T S
B S S S
B T T
S S S S T T S
G G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence L G F L G P I I K A E T G D K V Y V H L K N L A S R P Y T F H S H G I T Y Y K E H E G A I Y P D N T T D F Q R A D D K V Y P G E Q Y T Y M L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G T T S
T T
S S S
B
S S S B
T T S
S
G G G S S S S
B
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L A T E E Q S P G E G D G N C V T R I Y H S H I D A P K D I A S G L I G P L I I C K K D S L D K E K E K H I D R E F V V M F S V V D E N F S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) B
S T T S
T T S
S
S S T T
T T
B S S S S B T T
S
T T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence W Y L E D N I K T Y C S E P E K V D K D N E D F Q E S N R M Y S V N G Y T F G S L P G L S M C A E D R V K W Y L F G M G N E V D V H A A F F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S
G G G
T T
T T S S S
S S
T T
S T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence H G Q A L T N K N Y R I D T I N L F P A T L F D A Y M V A Q N P G E W M L S C Q N L N H L K A G L Q A F F Q V Q E C I R G K H V R H Y Y I A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S S S
S
T T
S
T

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence A E E I I W N Y A P S G I D I F T K E N L T A P G S D S A V F F E Q G T T R I G G S Y K K L V Y R E Y T D A S F T N R K E R G P E E E H L G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T
T T T T T T
S S S T T
S S S
S B S S S S T T S B
S G G G G G T

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence I L G P V I W A E V G D T I R V T F H N K G A Y P L S I E P I G V R F N K N N E G T Y Y S P V P P S A S H V A P T E T F T Y E W T V P K E V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S
T T
S S S
B
T S B
T T S
S S
B T T B B
T T
G G G

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence G P T N A D P V C L A K M Y Y S A V D P T K D I F T G L I G P M K I C K K G S L H A N G R Q K D V D K E F Y L F P T V F D E N E S L L L E D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T S
S
S S T
T T
B
T T S
B T T
S
G G G
T T

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence N I R M F T T A P D Q V D K E D E D F Q E S N K M H S M N G F M Y G N Q P G L T M C K G D S V V W Y L F S A G N E A D V H G I Y F S G N T Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S T T
T T
T T T B
T T
T T
S T T
T T

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence L W R G E R R D T A N L F P Q T S L T L H M W P D T E G T F N V E C L T T D H Y T G G M K Q K Y T V N Q C R R Q S E D S T F Y L G E R T Y Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T T
S
S T T
S
S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence I A A V E V E W D Y S P Q R E W E K E L H H L Q E Q N V S N A F L D K G E F Y I G S K Y K K V V Y R Q Y T D S T F R V P V E R K A E E E H L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
T
T T T
T T T
S S S T T
S B
G G G G G G

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence G I L G P Q L H A D V G D K V K I I F K N M A T R P Y S I H A H G V Q T E S S T V T P T L P G E T L T Y V W K I P E R S G A G T E D S A C I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T T
S S S
B
T T
B
S S S
B
T T
G G G S
S S S
S

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence P W A Y Y S T V D Q V K D L Y S G L I G P L I V C R R P R R K L E F A L L F L V F D E N E S W Y L D D N I K T Y S D H P E K V N K D D E E F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T T T
G G G
T T
S
G G G
T T

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence I E S N K M H A I N G R M F G N L Q G L T M H V G D E V N W Y L M G M G N E I D L H T V H F H G H S F Q Y K H R G V Y S S D V F D I F P G T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T B
T T
T T
S S T T
T T
S T T S
S
T T

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . .

Sequence Y Q T L E M F P R T P G I W L L H C H V T D H I H A G M E T T Y T V L Q N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	K	E	K	H	Y	Y	I	G	I	I	E	T	T	W	D	Y	A	S	D	H	G	E	K	K	L	I	S	V	D	T	E	H	S	N	I	Y	L	Q	N	G	P	D	R	I	G	R	L	Y	K	K	A	L	Y	L	Q	Y	T	D	E	T	F	R	T	T	I	E	K	P	V	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																			T	T	S							S	S			T	T	T	T	T	S		B	S	S	S		B	T	T											S	S	S	S	T	T	S						G	G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	L	G	F	L	G	P	I	I	K	A	E	T	G	D	K	V	Y	V	H	L	K	N	L	A	S	R	P	Y	T	F	H	S	H	G	I	T	Y	Y	K	E	H	E	G	A	I	Y	P	D	N	T	T	D	F	Q	R	A	D	D	K	V	Y	P	G	E	Q	Y	T	Y	M	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	T	T	S								T	T											S	S	S		B					S	S	S	B			T	T	S					S						G	G	G	S	S	S	S		B		T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	A	T	E	E	Q	S	P	G	E	G	D	G	N	C	V	T	R	I	Y	H	S	H	I	D	A	P	K	D	I	A	S	G	L	I	G	P	L	I	I	C	K	K	D	S	L	D	K	E	K	E	K	H	I	D	R	E	F	V	V	M	F	S	V	V	D	E	N	F	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	B			S	T	T	S			T	T	S		S										S	S							T	T										T	T		B	S	S	S	S	B	T	T		S												T	T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	W	Y	L	E	D	N	I	K	T	Y	C	S	E	P	E	K	V	D	K	D	N	E	D	F	Q	E	S	N	R	M	Y	S	V	N	G	Y	T	F	G	S	L	P	G	L	S	M	C	A	E	D	R	V	K	W	Y	L	F	G	M	G	N	E	V	D	V	H	A	A	F	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T										S		G	G	G			T	T							T	T					S	S	S			S	S									T	T												S	T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	H	G	Q	A	L	T	N	K	N	Y	R	I	D	T	I	N	L	F	P	A	T	L	F	D	A	Y	M	V	A	Q	N	P	G	E	W	M	L	S	C	Q	N	L	N	H	L	K	A	G	L	Q	A	F	F	Q	V	Q	E	C	I	R	G	K	H	V	R	H	Y	Y	I	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S					S	S	S			S						T	T											S																T
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	A	E	E	I	I	W	N	Y	A	P	S	G	I	D	I	F	T	K	E	N	L	T	A	P	G	S	D	S	A	V	F	F	E	Q	G	T	T	R	I	G	G	S	Y	K	K	L	V	Y	R	E	Y	T	D	A	S	F	T	N	R	K	E	R	G	P	E	E	E	H	L	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S		T	T				T	T	T	T			T	T		S	S	S	T	T							S	S	S				S										B	S	S	S	S	T	T	S	B					S	G	G	G	G	G	T
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	I	L	G	P	V	I	W	A	E	V	G	D	T	I	R	V	T	F	H	N	K	G	A	Y	P	L	S	I	E	P	I	G	V	R	F	N	K	N	N	E	G	T	Y	Y	S	P	V	P	P	S	A	S	H	V	A	P	T	E	T	F	T	Y	E	W	T	V	P	K	E	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	S								T	T											S	S	S		B						T	S	B			T	T	S		S	S								B	T	T	B	B		T	T											G	G	G
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	G	P	T	N	A	D	P	V	C	L	A	K	M	Y	Y	S	A	V	D	P	T	K	D	I	F	T	G	L	I	G	P	M	K	I	C	K	K	G	S	L	H	A	N	G	R	Q	K	D	V	D	K	E	F	Y	L	F	P	T	V	F	D	E	N	E	S	L	L	L	E	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S			T	T	S		S										S	S								T										T	T		B		T	T	S		B	T	T		S												G	G	G		T	T
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	N	I	R	M	F	T	T	A	P	D	Q	V	D	K	E	D	E	D	F	Q	E	S	N	K	M	H	S	M	N	G	F	M	Y	G	N	Q	P	G	L	T	M	C	K	G	D	S	V	V	W	Y	L	F	S	A	G	N	E	A	D	V	H	G	I	Y	F	S	G	N	T	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							S		S	T	T			T	T								T						T	T	B		T	T									T	T												S	T	T								T	T
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	L	W	R	G	E	R	R	D	T	A	N	L	F	P	Q	T	S	L	T	L	H	M	W	P	D	T	E	G	T	F	N	V	E	C	L	T	T	D	H	Y	T	G	G	M	K	Q	K	Y	T	V	N	Q	C	R	R	Q	S	E	D	S	T	F	Y	L	G	E	R	T	Y	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T				S						T	T											S										S						T	T											S							S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	I	A	A	V	E	V	E	W	D	Y	S	P	Q	R	E	W	E	K	E	L	H	H	L	Q	E	Q	N	V	S	N	A	F	L	D	K	G	E	F	Y	I	G	S	K	Y	K	K	V	V	Y	R	Q	Y	T	D	S	T	F	R	V	P	V	E	R	K	A	E	E	E	H	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S		S													T						T	T	T			T	T	T				S											S	S	T	T			S	B					G	G	G	G	G	G
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	G	I	L	G	P	Q	L	H	A	D	V	G	D	K	V	K	I	I	F	K	N	M	A	T	R	P	Y	S	I	H	A	H	G	V	Q	T	E	S	S	T	V	T	P	T	L	P	G	E	T	L	T	Y	V	W	K	I	P	E	R	S	G	A	G	T	E	D	S	A	C	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S								T	T											S	S	S		B					T	T		B		S	S	S					B		T	T											G	G	G	S			S	S	S		S
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	P	W	A	Y	Y	S	T	V	D	Q	V	K	D	L	Y	S	G	L	I	G	P	L	I	V	C	R	R	P	R	R	K	L	E	F	A	L	L	F	L	V	F	D	E	N	E	S	W	Y	L	D	D	N	I	K	T	Y	S	D	H	P	E	K	V	N	K	D	D	E	E	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T	T	T					T	T																										G	G	G		T	T										S		G	G	G			T	T
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	I	E	S	N	K	M	H	A	I	N	G	R	M	F	G	N	L	Q	G	L	T	M	H	V	G	D	E	V	N	W	Y	L	M	G	M	G	N	E	I	D	L	H	T	V	H	F	H	G	H	S	F	Q	Y	K	H	R	G	V	Y	S	S	D	V	F	D	I	F	P	G	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T						T	T	B		T	T									T	T											S	S	T	T								T	T						S	T	T	S					S						T	T
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.
Sequence	Y	Q	T	L	E	M	F	P	R	T	P	G	I	W	L	L	H	C	H	V	T	D	H	I	H	A	G	M	E	T	T	Y	T	V	L	Q	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										S										S							T