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  Protein Homology/analogY Recognition Engine V 2.2
 

Fold library entry viewer: c1hw3A_

Fold library idPDB HeaderMoleculeTitle
c1hw3A_PDB header: transferaseChain: A: PDB Molecule: thymidylate synthase;PDBTitle: structure of human thymidylate synthase suggests advantages2 of chemotherapy with noncompetitive inhibitors


Added to library: Tue Mar 16 12:12:00 2010
 
Links to external resources


 1........10.........20.........30.........40.........50.........60.........70
Sequence PPHGELQYLGQIQHILRGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGST
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Known secondary structure (DSSP)


T


TTS

SS




TTTT

T

 .........80.........90.........100.........110.........120.........130.........140
Sequence NAKELSSKGVGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMAWNPRDLPL
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Known secondary structure (DSSP) BTT


B

S
SBT




TTS

TT
SB

TT
S






GGGTTT
 .........150.........160.........170.........180.........190.........200.........210
Sequence MALPPHALQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNH
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Known secondary structure (DSSP) SSS


B

TTTTTTT
GGG
 .........220.........230.........240.........250.........
Sequence IEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKME
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Known secondary structure (DSSP) TTS






S


SGGG

GGGS










Download:PDB structure FASTA sequence

Hidden Markov model

Image coloured by rainbow N → C terminus
Interactive 3D view in JSmol


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Accessibility Statement
Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
 
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