PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1ekuA_

Fold library id	PDB Header	Molecule	Title
c1ekuA_	PDB header: immune system	Chain: A: PDB Molecule: interferon gamma;	PDBTitle: crystal structure of a biologically active single chain2 mutant of human ifn-gamma

Links to external resources
Added to library: Tue Mar 16 13:11:24 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M Q D P Y V K E A E N L K K Y F N A G H S D V A D N G T L F L G I L K N W K E E S D R K I M Q S Q I V S F Y F K L F K N F K D D Q S I Q K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T T T S S T T S
S
S S T
S T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V E T I K E D M N V K F F N S N K K K R D D F E K L T N Y S V T D L N V Q R K A I D E L I Q V M A E F S T E E Q Q E G P Y V K E A E N L K K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
T S
S S
T T S S S
S S T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence Y F N A G H S D V A D N G T L F L G I L K N W K E E S D R K I M Q S Q I V S F Y F K L F K N F K D D Q S I Q K S V E T I K E D M N V K F F N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T S T T T S
S S
S S T
S T T T T
T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . .

Sequence S N K K K R D D F E K L T N Y S V T D L N V Q R K A I H E L I Q V M A E L S P M L F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T S
T T
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	Q	D	P	Y	V	K	E	A	E	N	L	K	K	Y	F	N	A	G	H	S	D	V	A	D	N	G	T	L	F	L	G	I	L	K	N	W	K	E	E	S	D	R	K	I	M	Q	S	Q	I	V	S	F	Y	F	K	L	F	K	N	F	K	D	D	Q	S	I	Q	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S												T	T	T	T	S	S	T	T	S		S			S	S						T			S																					T	T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	E	T	I	K	E	D	M	N	V	K	F	F	N	S	N	K	K	K	R	D	D	F	E	K	L	T	N	Y	S	V	T	D	L	N	V	Q	R	K	A	I	D	E	L	I	Q	V	M	A	E	F	S	T	E	E	Q	Q	E	G	P	Y	V	K	E	A	E	N	L	K	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														T	T													T	S		S	S																		T	T	S	S	S					S	S	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	Y	F	N	A	G	H	S	D	V	A	D	N	G	T	L	F	L	G	I	L	K	N	W	K	E	E	S	D	R	K	I	M	Q	S	Q	I	V	S	F	Y	F	K	L	F	K	N	F	K	D	D	Q	S	I	Q	K	S	V	E	T	I	K	E	D	M	N	V	K	F	F	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T	T	T	S	T	T	T	S		S	S		S	S						T			S																					T	T	T	T																					T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.
Sequence	S	N	K	K	K	R	D	D	F	E	K	L	T	N	Y	S	V	T	D	L	N	V	Q	R	K	A	I	H	E	L	I	Q	V	M	A	E	L	S	P	M	L	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T													T	S		T	T											T							T