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 Protein Homology/analogY Recognition Engine V 2.0


 

Fold library entry viewer: c1e8zA_

Fold library idPDB HeaderMoleculeTitle
c1e8zA_PDB header: transferaseChain: A: PDB Molecule: phosphatidylinositol 3-kinase catalytic subunit;PDBTitle: structure determinants of phosphoinositide 3-kinase2 inhibition by wortmannin, ly294002, quercetin, myricetin3 and staurosporine


Added to library: Tue Mar 16 13:23:55 2010
 
Links to external resources


 1........10.........20.........30.........40.........50.........60.........70
Sequence SEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWK
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Known secondary structure (DSSP)

TS
TT

TT
SSSTS



B

S


T
 .........80.........90.........100.........110.........120.........130.........140
Sequence KIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTKMAKDFVLRVCGRDEYLVGETPIKNFQWVRHCL
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Known secondary structure (DSSP) T
TTS

SS


TT

TT




TTSS
B

SSS
GGGB
 .........150.........160.........170.........180.........190.........200.........210
Sequence KNGEEIHVVLDTPPDPALDEVRKEECDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSP
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Known secondary structure (DSSP) TT





GGGG







S
S



SS

TT


 .........220.........230.........240.........250.........260.........270.........280
Sequence KPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCLLYYVNLLLIDHRFLLRRGEYVLHMWQISGFNADKL
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Known secondary structure (DSSP)

SGGG

TT



SB
TTS
B


B





GGGG
 .........290.........300.........310.........320.........330.........340.........350
Sequence TSATNPDKENSMSISILLDNHPIARAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAY
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Known secondary structure (DSSP)




S
TTTS











S
TTS


TTT
GGG
 .........360.........370.........380.........390.........400.........410.........420
Sequence PKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHY
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Known secondary structure (DSSP) TTS
TT
TT
TS


TTSTT


TT

 .........430.........440.........450.........460.........470.........480.........490
Sequence LLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAML
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Known secondary structure (DSSP) GGG
SSSS


TTTTTS
 .........500.........510.........520.........530.........540.........550.........560
Sequence HDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIE
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Known secondary structure (DSSP) S

S




TTTTS
S
TT
GG
 .........570.........580.........590.........600.........610.........620.........630
Sequence KCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGC
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Known secondary structure (DSSP) G


SSS

S
TT
SS


SS
TT








 .........640.........650.........660.........670.........680.........690.........700
Sequence ISTGDKIGMIEIVKDATTIAKIQQSTVGNTGFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATF
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Known secondary structure (DSSP)
SSS


SST
S



SS
SS
 .........710.........720.........730.........740.........750.........760.........770
Sequence VLGIGDRHNDNIMITETGNLFHIDFGHERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHH
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Known secondary structure (DSSP) T




GGGTTS








SS


TT

SS


TT
 .........780.........790.........800.........810.........820.........830.........
Sequence TNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVL
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Known secondary structure (DSSP) TSS


TTTTTT

TTTTS




Download:PDB structure FASTA sequence

Hidden Markov model

Image coloured by rainbow N → C terminus
Interactive 3D view in JSmol


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Accessibility Statement
Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
 
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