PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1bw8A_

Fold library id	PDB Header	Molecule	Title
c1bw8A_	PDB header: peptide binding protein	Chain: A: PDB Molecule: protein (mu2 adaptin subunit);	PDBTitle: mu2 adaptin subunit (ap50) of ap2 adaptor (second domain),2 complexed with egfr internalization peptide fyralm

Links to external resources
Added to library: Tue Mar 16 12:05:36 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence I G W R R E G I K Y R R N E L F L D V L E S V N L L M S P Q G Q V L S A H V S G R V V M K S Y L S G M P E C K F G M N D K I K Q S I A I D D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S
S S
T T S
S S S
S
S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence C T F H Q C V R L S E R S I S F I P P D G E F E L M R Y R T T K D I I L P F R V I P L V R E V G R T K L E V K V V I K S N F K P S L L A Q K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T B
S
S S
S T T T
S
T T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I E V R I P T P L N T S G V Q V I C M K G K A K Y K A S E N A I V W K I K R M A G M K E S Q I S A E I E L L P T N D K K K W A R P P I S M N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S S T T T T S S
T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . .

Sequence F E V P F A P S G L K V R Y L K V F E P K L N Y S D H D V I K W V R Y I G R S G I Y E T R C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
T T
S S S S
G G G S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	I	G	W	R	R	E	G	I	K	Y	R	R	N	E	L	F	L	D	V	L	E	S	V	N	L	L	M	S	P	Q	G	Q	V	L	S	A	H	V	S	G	R	V	V	M	K	S	Y	L	S	G	M	P	E	C	K	F	G	M	N	D	K	I	K	Q	S	I	A	I	D	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T			S					S	S																	T	T	S																		S	S	S								S										S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	C	T	F	H	Q	C	V	R	L	S	E	R	S	I	S	F	I	P	P	D	G	E	F	E	L	M	R	Y	R	T	T	K	D	I	I	L	P	F	R	V	I	P	L	V	R	E	V	G	R	T	K	L	E	V	K	V	V	I	K	S	N	F	K	P	S	L	L	A	Q	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T	B													S												S	S				S											T	T	T												S		T	T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	E	V	R	I	P	T	P	L	N	T	S	G	V	Q	V	I	C	M	K	G	K	A	K	Y	K	A	S	E	N	A	I	V	W	K	I	K	R	M	A	G	M	K	E	S	Q	I	S	A	E	I	E	L	L	P	T	N	D	K	K	K	W	A	R	P	P	I	S	M	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T									S	S	S						T	T	T	T											S	S																T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
Sequence	F	E	V	P	F	A	P	S	G	L	K	V	R	Y	L	K	V	F	E	P	K	L	N	Y	S	D	H	D	V	I	K	W	V	R	Y	I	G	R	S	G	I	Y	E	T	R	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	S		T	T												S	S	S	S			G	G	G	S