Phyre 2 Results for Q9QXE4

Email	l.a.kelley@imperial.ac.uk
Description	Q9QXE4
Date	Tue Jul 30 12:59:04 BST 2013
Unique Job ID	3adef31b4b6bc701
Sequence	MFQRLNKMFV ... Download FASTA

Summary

Top model

Image coloured by rainbow N → C terminus

Model dimensions (Å):

X:17.182 Y:25.149 Z:23.072

Model (left) based on template c3absD_

Top template information

PDB header:lyase
Chain: D: PDB Molecule:ethanolamine ammonia-lyase light chain;
PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with adeninylpentylcobalamin and ethanolamine

Confidence and coverage

Confidence:

19.8%

Coverage:

20 residues ( 8% of your sequence) have been modelled with 19.8% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

Please note: You must be registered and logged in to use Phyrealarm.

Warning: 66% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M F Q R L N K M F V G E V T T S S S Q E P E F S E K E D D E W I L V D F I D T C P G F S A E E E E E D E D I G E E S S A

Secondary structure

SS confidence

Disorder ? ? ? ?
?
? ? ? ? ?
?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence E H T S V F S C L P A S L E C L T D T S D S C F L Q F E S C P M E E S W F I T P P P C F T A G G L T T I K V E T S P M E

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence N L L I E H P S M S V Y A V H N S C P G L S E A S C G N D E Y N S S G P R M E A Q S E M G K H I H C C V A A L A A Q A T

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . .

Sequence F L E Q P K S F R P S Q W I K G H S E R Q S L N R N G L R R Q N L T R D C H T R Q M K H S G W V V H Q P C P R Q Y N Y

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered ( 66%)

Alpha helix ( 33%)

Beta strand ( 6%)

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 3abs chain D

Region: 128 - 147
Aligned: 20
Modelled: 20
Confidence: 19.8%
Identity: 35%
PDB header:lyase
Chain: D: PDB Molecule:ethanolamine ammonia-lyase light chain;
PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with adeninylpentylcobalamin and ethanolamine

Phyre2

PDB 3any chain B

Region: 128 - 147
Aligned: 20
Modelled: 20
Confidence: 19.8%
Identity: 35%
PDB header:lyase
Chain: B: PDB Molecule:ethanolamine ammonia-lyase light chain;
PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with cn-cbl and (r)-2-amino-1-propanol

Phyre2

PDB 3hxr chain A

Region: 13 - 39
Aligned: 27
Modelled: 27
Confidence: 19.5%
Identity: 22%
PDB header:structural protein
Chain: A: PDB Molecule:nucleoporin nup120;
PDBTitle: nucleoporin nup120 from s.cerevisiae (aa 1-757)

Phyre2

PDB 3ups chain A

Region: 26 - 38
Aligned: 13
Modelled: 13
Confidence: 18.0%
Identity: 31%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:iojap-like protein;
PDBTitle: crystal structure of iojap-like protein from zymomonas mobilis

Phyre2

PDB 2o5a chain A domain 1

Region: 27 - 38
Aligned: 12
Modelled: 12
Confidence: 17.7%
Identity: 42%
Fold: Nucleotidyltransferase
Superfamily: Nucleotidyltransferase
Family: Iojap/YbeB-like

Phyre2

PDB 3s63 chain B

Region: 218 - 239
Aligned: 22
Modelled: 22
Confidence: 16.2%
Identity: 32%
PDB header:lipid binding protein
Chain: B: PDB Molecule:saposin-like protein;
PDBTitle: saposin-like protein na-slp-1

Phyre2

PDB 2id1 chain A domain 1

Region: 27 - 38
Aligned: 12
Modelled: 12
Confidence: 14.7%
Identity: 58%
Fold: Nucleotidyltransferase
Superfamily: Nucleotidyltransferase
Family: Iojap/YbeB-like

Phyre2

PDB 1oa8 chain A

Region: 101 - 125
Aligned: 25
Modelled: 25
Confidence: 12.6%
Identity: 32%
Fold: AXH domain
Superfamily: AXH domain
Family: AXH domain

Phyre2

PDB 1sr4 chain A

Region: 93 - 102
Aligned: 10
Modelled: 10
Confidence: 10.8%
Identity: 30%
Fold: beta-Trefoil
Superfamily: Ricin B-like lectins
Family: Ricin B-like

Phyre2

PDB 1sr4 chain A

Region: 93 - 102
Aligned: 10
Modelled: 10
Confidence: 10.8%
Identity: 30%
PDB header:toxin
Chain: A: PDB Molecule:cytolethal distending toxin subunit a;
PDBTitle: crystal structure of the haemophilus ducreyi cytolethal2 distending toxin

Phyre2

PDB 1nlq chain A

Region: 7 - 114
Aligned: 92
Modelled: 103
Confidence: 10.7%
Identity: 16%
Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily: Nucleoplasmin-like core domain
Family: Nucleoplasmin-like core domain

Phyre2

PDB 3pro chain C domain 2

Region: 94 - 100
Aligned: 7
Modelled: 7
Confidence: 9.1%
Identity: 43%
Fold: Alpha-lytic protease prodomain-like
Superfamily: Alpha-lytic protease prodomain
Family: Alpha-lytic protease prodomain

Phyre2

PDB 3ce8 chain A

Region: 119 - 136
Aligned: 18
Modelled: 18
Confidence: 8.6%
Identity: 28%
PDB header:unknown function
Chain: A: PDB Molecule:putative pii-like nitrogen regulatory protein;
PDBTitle: crystal structure of a duf3240 family protein (sbal_0098) from2 shewanella baltica os155 at 2.40 a resolution

Phyre2

PDB 3npe chain A

Region: 24 - 44
Aligned: 21
Modelled: 21
Confidence: 8.5%
Identity: 33%
PDB header:oxidoreductase
Chain: A: PDB Molecule:9-cis-epoxycarotenoid dioxygenase 1, chloroplastic;
PDBTitle: structure of vp14 in complex with oxygen

Phyre2

PDB 1v5x chain A

Region: 99 - 116
Aligned: 18
Modelled: 18
Confidence: 8.0%
Identity: 28%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 1pii chain A domain 1

Region: 98 - 115
Aligned: 18
Modelled: 18
Confidence: 7.7%
Identity: 22%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 2biw chain C

Region: 22 - 42
Aligned: 21
Modelled: 21
Confidence: 7.4%
Identity: 24%
PDB header:oxidoreductase
Chain: C: PDB Molecule:apocarotenoid-cleaving oxygenase;
PDBTitle: crystal structure of apocarotenoid cleavage oxygenase from2 synechocystis, native enzyme

Phyre2

PDB 3fsn chain A

Region: 22 - 34
Aligned: 13
Modelled: 13
Confidence: 7.0%
Identity: 31%
PDB header:isomerase
Chain: A: PDB Molecule:retinal pigment epithelium-specific 65 kda protein;
PDBTitle: crystal structure of rpe65 at 2.14 angstrom resolution

Phyre2

PDB 1gl5 chain A

Region: 23 - 45
Aligned: 23
Modelled: 23
Confidence: 6.9%
Identity: 22%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 1a4i chain A domain 1

Region: 97 - 124
Aligned: 23
Modelled: 28
Confidence: 6.8%
Identity: 39%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Aminoacid dehydrogenase-like, C-terminal domain

Phyre2