Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionO13529
DateMon Jul 2 19:10:08 BST 2012
Unique Job ID5ac667eaf1701a94

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3k1qB_
Top template information
PDB header:virus
Chain: B: PDB Molecule:vp3a, the building block protein of inner shell;
PDBTitle: backbone model of an aquareovirus virion by cryo-electron2 microscopy and bioinformatics
Confidence and coverage
Confidence: 54.4% Coverage: 46%
70 residues ( 46% of your sequence) have been modelled with 54.4% confidence by the single highest scoring template.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNRSFHFLIKYIYIHVLLVFYFHIKQQAIMPFFIFFFSSFDGLSFDLRVVAFLAKHVFVG
Secondary structure 




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Disorder  ????























































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   .........70.........80.........90.........100.........110.........120
Sequence  VCSPFFVVGFFGSSRVVVTEWLSKLVLPPPPVSITQVFSLSRKRGEFSSGYILIINPYKS
Secondary structure 
















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   .........130.........140.........150.
Sequence  FLRSLLDFSIFNNTAKNKSSTFTLNLEDVSK
Secondary structure 








SS confidence 






























Disorder 










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???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3k1q chain B

3D model

Region: 76 - 146
Aligned: 70
Modelled: 71
Confidence: 54.4%
Identity: 33%
PDB header:virus
Chain: B: PDB Molecule:vp3a, the building block protein of inner shell;
PDBTitle: backbone model of an aquareovirus virion by cryo-electron2 microscopy and bioinformatics

Phyre2

PDB 3k1q chain C

3D model

Region: 76 - 146
Aligned: 70
Modelled: 71
Confidence: 49.5%
Identity: 33%
PDB header:virus
Chain: C: PDB Molecule:vp3b, the building block protein of inner shell;
PDBTitle: backbone model of an aquareovirus virion by cryo-electron2 microscopy and bioinformatics

Phyre2

PDB 2cse chain W

3D model

Region: 76 - 146
Aligned: 70
Modelled: 71
Confidence: 25.4%
Identity: 23%
PDB header:virus
Chain: W: PDB Molecule:major core protein lambda 1;
PDBTitle: features of reovirus outer-capsid protein mu1 revealed by2 electron and image reconstruction of the virion at 7.0-a3 resolution

Phyre2

PDB 3lpe chain F

3D model

Region: 109 - 130
Aligned: 22
Modelled: 71
Confidence: 20.7%
Identity: 32%
PDB header:transferase
Chain: F: PDB Molecule:dna-directed rna polymerase subunit e'';
PDBTitle: crystal structure of spt4/5ngn heterodimer complex from methanococcus2 jannaschii

Phyre2

PDB 1ryq chain A

3D model

Region: 109 - 130
Aligned: 22
Modelled: 22
Confidence: 17.8%
Identity: 9%
Fold: Rubredoxin-like
Superfamily: RNA polymerase subunits
Family: RpoE2-like

Phyre2

PDB 1p8b chain A

3D model

Region: 60 - 65
Aligned: 6
Modelled: 6
Confidence: 13.9%
Identity: 100%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: omega toxin-like
Family: Albumin 1

Phyre2

PDB 1ju8 chain A

3D model

Region: 60 - 65
Aligned: 6
Modelled: 6
Confidence: 13.0%
Identity: 83%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: omega toxin-like
Family: Albumin 1

Phyre2

PDB 2q22 chain A domain 1

3D model

Region: 46 - 92
Aligned: 42
Modelled: 47
Confidence: 12.8%
Identity: 17%
Fold: Ava3019-like
Superfamily: Ava3019-like
Family: Ava3019-like

Phyre2

PDB 1v95 chain A

3D model

Region: 85 - 125
Aligned: 38
Modelled: 47
Confidence: 10.8%
Identity: 24%
Fold: Anticodon-binding domain-like
Superfamily: Class II aaRS ABD-related
Family: Anticodon-binding domain of Class II aaRS

Phyre2

PDB 1ucv chain A

3D model

Region: 72 - 88
Aligned: 17
Modelled: 17
Confidence: 8.8%
Identity: 35%
Fold: SAM domain-like
Superfamily: SAM/Pointed domain
Family: SAM (sterile alpha motif) domain

Phyre2

PDB 1okg chain A domain 3

3D model

Region: 70 - 91
Aligned: 16
Modelled: 22
Confidence: 7.6%
Identity: 50%
Fold: FKBP-like
Superfamily: FKBP-like
Family: 3-mercaptopyruvate sulfurtransferase, C-terminal domain

Phyre2

PDB 1v54 chain D

3D model

Region: 65 - 96
Aligned: 32
Modelled: 22
Confidence: 7.0%
Identity: 19%
Fold: Single transmembrane helix
Superfamily: Mitochondrial cytochrome c oxidase subunit IV
Family: Mitochondrial cytochrome c oxidase subunit IV

Phyre2

PDB 2y69 chain Q

3D model

Region: 65 - 96
Aligned: 32
Modelled: 32
Confidence: 6.6%
Identity: 19%
PDB header:electron transport
Chain: Q: PDB Molecule:cytochrome c oxidase subunit 4 isoform 1;
PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen

Phyre2

PDB 2l27 chain B

3D model

Region: 90 - 102
Aligned: 13
Modelled: 13
Confidence: 6.1%
Identity: 46%
PDB header:membrane protein, peptide binding protei
Chain: B: PDB Molecule:peptide agonist;
PDBTitle: nmr structure of the ecd1 of crf-r1 in complex with a peptide agonist

Phyre2

PDB 1v0d chain A

3D model

Region: 115 - 132
Aligned: 17
Modelled: 18
Confidence: 5.9%
Identity: 47%
PDB header:hydrolase
Chain: A: PDB Molecule:dna fragmentation factor 40 kda subunit;
PDBTitle: crystal structure of caspase-activated dnase (cad)

Phyre2

PDB 1v0d chain A

3D model

Region: 115 - 132
Aligned: 17
Modelled: 18
Confidence: 5.9%
Identity: 47%
Fold: His-Me finger endonucleases
Superfamily: His-Me finger endonucleases
Family: Caspase-activated DNase, CAD (DffB, DFF40)

Phyre2

PDB 2rmf chain A

3D model

Region: 90 - 102
Aligned: 13
Modelled: 13
Confidence: 5.5%
Identity: 46%
PDB header:hormone
Chain: A: PDB Molecule:urocortin;
PDBTitle: human urocortin 1

Phyre2
1

c3k1qB_
2

c3k1qC_
3

c2cseW_
4

c3lpeF_
5

d1ryqa_
6

d1p8ba_
7

d1ju8a_
8

d2q22a1
9

d1v95a_
10

d1ucva_
11

d1okga3
12

d1v54d_
13

c2y69Q_
14

c2l27B_
15

c1v0dA_
16

d1v0da_
17

c2rmfA_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3k1qB_



54.4 33 PDB header:virus
Chain: B: PDB Molecule:vp3a, the building block protein of inner shell;
PDBTitle: backbone model of an aquareovirus virion by cryo-electron2 microscopy and bioinformatics
2c3k1qC_



49.5 33 PDB header:virus
Chain: C: PDB Molecule:vp3b, the building block protein of inner shell;
PDBTitle: backbone model of an aquareovirus virion by cryo-electron2 microscopy and bioinformatics
3c2cseW_



25.4 23 PDB header:virus
Chain: W: PDB Molecule:major core protein lambda 1;
PDBTitle: features of reovirus outer-capsid protein mu1 revealed by2 electron and image reconstruction of the virion at 7.0-a3 resolution
4c3lpeF_



20.7 32 PDB header:transferase
Chain: F: PDB Molecule:dna-directed rna polymerase subunit e'';
PDBTitle: crystal structure of spt4/5ngn heterodimer complex from methanococcus2 jannaschii
5d1ryqa_



17.8 9 Fold:Rubredoxin-like
Superfamily:RNA polymerase subunits
Family:RpoE2-like
6d1p8ba_



13.9 100 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:omega toxin-like
Family:Albumin 1
7d1ju8a_



13.0 83 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:omega toxin-like
Family:Albumin 1
8d2q22a1



12.8 17 Fold:Ava3019-like
Superfamily:Ava3019-like
Family:Ava3019-like
9d1v95a_



10.8 24 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
10d1ucva_



8.8 35 Fold:SAM domain-like
Superfamily:SAM/Pointed domain
Family:SAM (sterile alpha motif) domain
11d1okga3



7.6 50 Fold:FKBP-like
Superfamily:FKBP-like
Family:3-mercaptopyruvate sulfurtransferase, C-terminal domain
12d1v54d_



7.0 19 Fold:Single transmembrane helix
Superfamily:Mitochondrial cytochrome c oxidase subunit IV
Family:Mitochondrial cytochrome c oxidase subunit IV
13c2y69Q_



6.6 19 PDB header:electron transport
Chain: Q: PDB Molecule:cytochrome c oxidase subunit 4 isoform 1;
PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen
14c2l27B_



6.1 46 PDB header:membrane protein, peptide binding protei
Chain: B: PDB Molecule:peptide agonist;
PDBTitle: nmr structure of the ecd1 of crf-r1 in complex with a peptide agonist
15c1v0dA_



5.9 47 PDB header:hydrolase
Chain: A: PDB Molecule:dna fragmentation factor 40 kda subunit;
PDBTitle: crystal structure of caspase-activated dnase (cad)
16d1v0da_



5.9 47 Fold:His-Me finger endonucleases
Superfamily:His-Me finger endonucleases
Family:Caspase-activated DNase, CAD (DffB, DFF40)
17c2rmfA_



5.5 46 PDB header:hormone
Chain: A: PDB Molecule:urocortin;
PDBTitle: human urocortin 1

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite