Phyre 2 Results for P68805

Email	l.a.kelley@imperial.ac.uk
Description	P68805
Date	Tue Jul 17 17:05:13 BST 2012
Unique Job ID	d98c7c601a50ae90

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2oarA_

Top template information

PDB header:membrane protein
Chain: A: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: mechanosensitive channel of large conductance (mscl)

Confidence and coverage

Confidence:

100.0%

Coverage:

98%

117 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M L K E F K E F A L K G N V L D L A I A V V M G A A F N K I I S S L V E N I I M P L I G K I F G S V D F A K E W S F W G

Secondary structure

SS confidence

Disorder ? ?
? ? ?
?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence I K Y G L F I Q S V I D F I I I A F A L F I F V K I A N T L M K K E E A E E E A V V E E N V V L L T E I R D L L R E K K

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ?
? ? ?

Disorder confidence

Sequence

Secondary structure

SS confidence

Disorder

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2oar chain A

Region: 1 - 119
Aligned: 117
Modelled: 119
Confidence: 100.0%
Identity: 44%
PDB header:membrane protein
Chain: A: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: mechanosensitive channel of large conductance (mscl)

Phyre2

PDB 3hzq chain A

Region: 1 - 94
Aligned: 94
Modelled: 94
Confidence: 100.0%
Identity: 99%
PDB header:membrane protein
Chain: A: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: structure of a tetrameric mscl in an expanded intermediate2 state

Phyre2

PDB 2oar chain A domain 1

Region: 11 - 113
Aligned: 101
Modelled: 103
Confidence: 100.0%
Identity: 42%
Fold: Gated mechanosensitive channel
Superfamily: Gated mechanosensitive channel
Family: Gated mechanosensitive channel

Phyre2

PDB 3qnq chain D

Region: 47 - 102
Aligned: 56
Modelled: 56
Confidence: 81.4%
Identity: 20%
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Phyre2

PDB 2b3w chain A domain 1

Region: 107 - 120
Aligned: 14
Modelled: 14
Confidence: 23.8%
Identity: 43%
Fold: YbiA-like
Superfamily: YbiA-like
Family: YbiA-like

Phyre2

PDB 1vdf chain B

Region: 107 - 119
Aligned: 13
Modelled: 13
Confidence: 21.4%
Identity: 38%
PDB header:extracellular matrix protein
Chain: B: PDB Molecule:cartilage oligomeric matrix protein;
PDBTitle: assembly domain of cartilage oligomeric matrix protein

Phyre2

PDB 3t98 chain A

Region: 105 - 120
Aligned: 16
Modelled: 16
Confidence: 20.0%
Identity: 31%
PDB header:protein transport
Chain: A: PDB Molecule:nuclear pore complex protein nup54;
PDBTitle: molecular architecture of the transport channel of the nuclear pore2 complex: nup54/nup58

Phyre2

PDB 1q1v chain A

Region: 96 - 119
Aligned: 24
Modelled: 24
Confidence: 11.6%
Identity: 17%
Fold: Another 3-helical bundle
Superfamily: DEK C-terminal domain
Family: DEK C-terminal domain

Phyre2

PDB 2rdd chain B

Region: 67 - 94
Aligned: 28
Modelled: 28
Confidence: 10.3%
Identity: 7%
PDB header:membrane protein/transport protein
Chain: B: PDB Molecule:upf0092 membrane protein yajc;
PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix.

Phyre2

PDB 1xpj chain A

Region: 108 - 120
Aligned: 13
Modelled: 13
Confidence: 10.1%
Identity: 38%
Fold: HAD-like
Superfamily: HAD-like
Family: Hypothetical protein VC0232

Phyre2

PDB 1sh0 chain A

Region: 24 - 40
Aligned: 17
Modelled: 17
Confidence: 9.9%
Identity: 12%
Fold: DNA/RNA polymerases
Superfamily: DNA/RNA polymerases
Family: RNA-dependent RNA-polymerase

Phyre2

PDB 2uut chain A

Region: 24 - 40
Aligned: 17
Modelled: 17
Confidence: 8.7%
Identity: 24%
PDB header:hydrolase
Chain: A: PDB Molecule:rna-directed rna polymerase;
PDBTitle: the 2.4 angstrom resolution structure of the d346g mutant2 of the sapporo virus rdrp polymerase

Phyre2

PDB 2lna chain A

Region: 2 - 14
Aligned: 13
Modelled: 13
Confidence: 8.1%
Identity: 38%
PDB header:hydrolase
Chain: A: PDB Molecule:afg3-like protein 2;
PDBTitle: solution nmr structure of the mitochondrial inner membrane domain2 (residues 164-251), ftsh_ext, from the paraplegin-like protein afg3l23 from homo sapiens, northeast structural genomics consortium target4 hr6741a

Phyre2

PDB 2caz chain B domain 1

Region: 78 - 120
Aligned: 43
Modelled: 43
Confidence: 8.0%
Identity: 14%
Fold: Long alpha-hairpin
Superfamily: Endosomal sorting complex assembly domain
Family: VPS28 N-terminal domain

Phyre2

PDB 2caz chain B

Region: 78 - 120
Aligned: 43
Modelled: 43
Confidence: 8.0%
Identity: 14%
PDB header:protein transport
Chain: B: PDB Molecule:vacuolar protein sorting-associated protein
PDBTitle: escrt-i core

Phyre2

PDB 2b43 chain D

Region: 24 - 40
Aligned: 17
Modelled: 17
Confidence: 8.0%
Identity: 12%
PDB header:viral protein
Chain: D: PDB Molecule:non-structural polyprotein;
PDBTitle: crystal structure of the norwalk virus rna dependent rna polymerase2 from strain hu/nlv/dresden174/1997/ge

Phyre2

PDB 3m91 chain B

Region: 104 - 119
Aligned: 16
Modelled: 16
Confidence: 7.4%
Identity: 50%
PDB header:hydrolase regulator
Chain: B: PDB Molecule:prokaryotic ubiquitin-like protein pup;
PDBTitle: crystal structure of the prokaryotic ubiquitin-like protein (pup)2 complexed with the amino terminal coiled coil of the mycobacterium3 tuberculosis proteasomal atpase mpa

Phyre2

PDB 3m9d chain I

Region: 99 - 119
Aligned: 21
Modelled: 21
Confidence: 6.8%
Identity: 48%
PDB header:chaperone
Chain: I: PDB Molecule:prokaryotic ubiquitin-like protein pup;
PDBTitle: crystal structure of the prokaryotic ubiquintin-like protein pup2 complexed with the hexameric proteasomal atpase mpa which includes3 the amino terminal coiled coil domain and the inter domain

Phyre2

PDB 1khv chain A

Region: 24 - 40
Aligned: 17
Modelled: 17
Confidence: 6.8%
Identity: 24%
Fold: DNA/RNA polymerases
Superfamily: DNA/RNA polymerases
Family: RNA-dependent RNA-polymerase

Phyre2

PDB 1c94 chain B

Region: 108 - 120
Aligned: 13
Modelled: 13
Confidence: 6.7%
Identity: 38%
PDB header:gene regulation
Chain: B: PDB Molecule:retro-gcn4 leucine zipper;
PDBTitle: reversing the sequence of the gcn4 leucine zipper does not2 affect its fold.

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	L	K	E	F	K	E	F	A	L	K	G	N	V	L	D	L	A	I	A	V	V	M	G	A	A	F	N	K	I	I	S	S	L	V	E	N	I	I	M	P	L	I	G	K	I	F	G	S	V	D	F	A	K	E	W	S	F	W	G
Secondary structure
SS confidence
Disorder	?	?																																												?	?	?		?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	I	K	Y	G	L	F	I	Q	S	V	I	D	F	I	I	I	A	F	A	L	F	I	F	V	K	I	A	N	T	L	M	K	K	E	E	A	E	E	E	A	V	V	E	E	N	V	V	L	L	T	E	I	R	D	L	L	R	E	K	K
Secondary structure
SS confidence
Disorder																															?	?	?	?	?	?	?	?	?	?	?																	?	?	?
Disorder confidence


Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence