Return to main results Retrieve Phyre Job Id

Job DescriptionP33594
Confidence100.00%DateThu Jan 5 11:52:19 GMT 2012
Rank15Aligned Residues235
% Identity29%Templatec3g5uB_
PDB info PDB header:membrane proteinChain: B: PDB Molecule:multidrug resistance protein 1a; PDBTitle: structure of p-glycoprotein reveals a molecular basis for2 poly-specific drug binding
Resolution3.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   4.....10.........20.........30.........40.........50.........60.........70.........80...
Predicted Secondary structure 
















































Query SS confidence 















































































Query Sequence  LNISGLSHHYAHGGFNGKHQHQAVLNNVSLTLKSGETVALLGRSGCGKSTLARLLVGLESPAQGNISWRGEPLAKLNRAQ
Query Conservation 
   


  
              
  

  
  

   


 








  
 
      
 
   
          
Alig confidence 











......


























































...
Template Conservation 
    
   
  ......     

  

  
  

 




 








  
 
      
 
 
 
  
    ...
Template Sequence  VQFSGVVFNYPT. . . . . . RPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLN. . .
Template Known Secondary structure 

S
......GGG

SS


SSS
SSSTTTTSS

SSSSS
BTSS
...
Template Predicted Secondary structure 

......



























...
Template SS confidence 















































































   1031........1040.. .......1050.........1060.........1070.........1080.........1090.........1100.
 
   84.....90.........100.........110.........120..... ....130.........140.........150........
Predicted Secondary structure 

























.....

























Query SS confidence 









































. . . . .
































Query Sequence  RKAFRRDIQMVFQDSISAVNPRKTVREILREPMRHLLSLKKS. . . . . EQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQ
Query Conservation         
  
                               .....                          

 
   
Alig confidence 

















...




















.....
































Template Conservation     

  
  


   

...  





             
   
    
   
  
  


  
   
  

 



Template Sequence  VQWLRAQLGIVSQEPILF. . . DCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQ
Template Known Secondary structure  TTS
SS



...SSBT


SS



T
SSTTTGGG
B
STTS
SS
Template Predicted Secondary structure 






...





























Template SS confidence 















































































   1102.......1110......... 1120.........1130.........1140.........1150.........1160.........1170........
 
   159160.........170.........180.........190.........200.........210.........220.........230........
Predicted Secondary structure 
























Query SS confidence 















































































Query Sequence  RVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQVVGE
Query Conservation 

 

 

   
 







 


      
   
  
    
 


 


    
    
 
 

  
 
   
   
Alig confidence 








































..















.



















Template Conservation 

 





    








 

      
   
     ..  


 


       . 
 
 

  
 
 
 
    
Template Sequence  RIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKARE. . GRTCIVIAHRLSTIQN. ADLIVVIQNGKVKEHGTHQQ
Template Known Secondary structure 

SSS
SSS

SS..SS

S
TTGGGS.
STB
Template Predicted Secondary structure 











..




.





Template SS confidence 















































































   11791180.........1190.........1200.........1210......... 1220.........1230..... ....1240.........1250.....
 
   239240.........250...
Predicted Secondary structure 




Query SS confidence 














Query Sequence  KLTFSSDAGRVLQNA
Query Conservation                 
Alig confidence 














Template Conservation 
    
    
   
Template Sequence  LLAQKGIYFSMVSVQ
Template Known Secondary structure  S
S
Template Predicted Secondary structure 



Template SS confidence 














   1256...1260.........1270
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions