Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	F	A	W	I	T	D	P	N	A	W	L	A	L	G	T	L	T	L	L	E	I	V	L	G	I	D	N	I	I	F	L	S	L	V	V	A	K	L	P	T	A	Q	R	A	H	A	R	R	L	G	L	A	G	A	M	V	M	R
Secondary structure
SS confidence
Disorder		?	?				?	?																															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	A	L	L	A	S	I	A	W	V	T	R	L	T	N	P	L	F	T	I	F	S	Q	E	I	S	A	R	D	L	I	L	L	L	G	G	L	F	L	I	W	K	A	S	K	E	I	H	E	S	I	E	G	E	E	E	G	L	K	T
Secondary structure
SS confidence
Disorder																																																		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	V	S	S	F	L	G	A	I	V	Q	I	M	L	L	D	I	I	F	S	L	D	S	V	I	T	A	V	G	L	S	D	H	L	F	I	M	M	A	A	V	V	I	A	V	G	V	M	M	F	A	A	R	S	I	G	D	F	V	E
Secondary structure
SS confidence
Disorder		?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
Sequence		R	H	P	S	V	K	M	L	A	L	S	F	L	I	L	V	G	F	T	L	I	L	E	S	F	D	I	H	V	P	K	G	Y	I	Y	F	A	M	F	F	S	I	A	V	E	S	L	N	L	I	R	N	K	K	N	P	L
Secondary structure
SS confidence
Disorder																																																					?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ke4 chain A Region: 37 - 49 Aligned: 13 Modelled: 13 Confidence: 43.0% Identity: 23% PDB header:membrane protein Chain: A: PDB Molecule:cdc42-interacting protein 4; PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4 Phyre2 PDB 3bz2 chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii (part 22 of 2). this file contains second monomer of psii dimer Phyre2 PDB 2axt chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: crystal structure of photosystem ii from thermosynechococcus elongatus Phyre2 PDB 3prr chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii in complex with2 terbutryn (part 2 of 2). this file contains second monomer of psii3 dimer Phyre2 PDB 1s5l chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: architecture of the photosynthetic oxygen evolving center Phyre2 PDB 3kzi chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of monomeric form of cyanobacterial photosystem ii Phyre2 PDB 2axt chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: crystal structure of photosystem ii from thermosynechococcus elongatus Phyre2 PDB 3prq chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii in complex with2 terbutryn (part 1 of 2). this file contains first monomer of psii3 dimer Phyre2 PDB 3bz1 chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii (part 12 of 2). this file contains first monomer of psii dimer Phyre2 PDB 3a0h chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of i-substituted photosystem ii complex Phyre2 PDB 1s5l chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: architecture of the photosynthetic oxygen evolving center Phyre2 PDB 3a0h chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of i-substituted photosystem ii complex Phyre2 PDB 3arc chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution Phyre2 PDB 3a0b chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of br-substituted photosystem ii complex Phyre2 PDB 2axt chain L domain 1 Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.6% Identity: 24% Fold: Single transmembrane helix Superfamily: Photosystem II reaction center protein L, PsbL Family: PsbL-like Phyre2 PDB 2gfp chain A Region: 9 - 227 Aligned: 219 Modelled: 219 Confidence: 6.6% Identity: 9% PDB header:membrane protein Chain: A: PDB Molecule:multidrug resistance protein d; PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli Phyre2 PDB 3a0b chain L Region: 39 - 63 Aligned: 25 Modelled: 25 Confidence: 6.4% Identity: 24% PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of br-substituted photosystem ii complex Phyre2 PDB 3arc chain L Region: 41 - 63 Aligned: 23 Modelled: 23 Confidence: 5.7% Identity: 26% PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution Phyre2 1 c2ke4A_ 2 c3bz2L_ 3 c2axtL_ 4 c3prrL_ 5 c1s5lL_ 6 c3kziL_ 7 c2axtl_ 8 c3prqL_ 9 c3bz1L_ 10 c3a0hL_ 11 c1s5ll_ 12 c3a0hl_ 13 c3arcL_ 14 c3a0bl_ 15 d2axtl1 16 c2gfpA_ 17 c3a0bL_ 18 c3arcl_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2ke4A_ 43.0 23 PDB header:membrane protein Chain: A: PDB Molecule:cdc42-interacting protein 4; PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4 2 c3bz2L_ 6.6 24 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii (part 22 of 2). this file contains second monomer of psii dimer 3 c2axtL_ 6.6 24 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: crystal structure of photosystem ii from thermosynechococcus elongatus 4 c3prrL_ 6.6 24 PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii in complex with2 terbutryn (part 2 of 2). this file contains second monomer of psii3 dimer 5 c1s5lL_ 6.6 24 PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: architecture of the photosynthetic oxygen evolving center 6 c3kziL_ 6.6 24 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of monomeric form of cyanobacterial photosystem ii 7 c2axtl_ 6.6 24 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: crystal structure of photosystem ii from thermosynechococcus elongatus 8 c3prqL_ 6.6 24 PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii in complex with2 terbutryn (part 1 of 2). this file contains first monomer of psii3 dimer 9 c3bz1L_ 6.6 24 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of cyanobacterial photosystem ii (part 12 of 2). this file contains first monomer of psii dimer 10 c3a0hL_ 6.6 24 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of i-substituted photosystem ii complex 11 c1s5ll_ 6.6 24 PDB header:photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center l protein; PDBTitle: architecture of the photosynthetic oxygen evolving center 12 c3a0hl_ 6.6 24 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of i-substituted photosystem ii complex 13 c3arcL_ 6.6 24 PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution 14 c3a0bl_ 6.6 24 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of br-substituted photosystem ii complex 15 d2axtl1 6.6 24 Fold:Single transmembrane helix Superfamily:Photosystem II reaction center protein L, PsbL Family:PsbL-like 16 c2gfpA_ 6.6 9 PDB header:membrane protein Chain: A: PDB Molecule:multidrug resistance protein d; PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli 17 c3a0bL_ 6.4 24 PDB header:electron transport Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of br-substituted photosystem ii complex 18 c3arcl_ 5.7 26 PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0