Job Description P20083 Confidence 99.84% Date Thu Jan 5 11:37:45 GMT 2012 Rank 27 Aligned Residues 349 % Identity 14% Template c2q2eB_ PDB info PDB header:isomerase Chain: B: PDB Molecule:type 2 dna topoisomerase 6 subunit b; PDBTitle: crystal structure of the topoisomerase vi holoenzyme from2 methanosarcina mazei Resolution 4.00 Å

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		8	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30				.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.		.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.					.	.	.	.	.	70	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																									.	.	.																	.																			.	.	.	.
Query SS confidence																									.	.	.																	.																			.	.	.	.
Query Sequence		D	A	I	E	V	L	T	G	L	E	P	V	R	R	R	P	G	M	Y	T	D	T	T	.	.	.	R	P	N	H	L	G	Q	E	V	I	D	N	S	V	D	E	.	A	L	A	G	H	A	K	R	V	D	V	I	L	H	A	D	Q	S	.	.	.	.	L	E	V	I	D	D	G	R	G	M	P	V	D	I	H
Query Conservation																									.	.	.																	.																			.	.	.	.
Alig confidence																									.	.	.																	.																			.	.	.	.															.
Template Conservation																																																																																	.
Template Sequence		K	K	Q	K	S	I	S	V	A	E	F	F	E	K	N	R	Q	I	L	G	F	D	S	A	P	R	S	L	I	T	T	V	K	E	A	V	D	N	A	L	D	A	C	E	E	A	G	I	L	P	D	I	L	V	Q	V	E	R	T	G	P	D	Y	V	T	V	I	I	E	D	N	G	P	G	I	V	R	E	Q	.
Template Known Secondary structure							S		S							S	T	T	T	S	S		S	S																					T	T	T	S		S											T	T	T										S					G	G	G	.
Template Predicted Secondary structure																																																																																	.
Template SS confidence
		11	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.			.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.				.	.	150	.	.	.	.
Predicted Secondary structure																																						.	.																																	.	.	.
Query SS confidence																																						.	.																																	.	.	.
Query Sequence		P	E	E	G	V	P	A	V	E	L	I	L	C	R	L	H	A	G	G	K	F	S	N	K	N	Y	Q	F	S	G	G	L	H	G	V	G	.	.	I	S	V	V	N	A	L	S	K	R	V	E	V	N	V	R	R	D	G	Q	V	Y	N	I	A	F	E	N	G	E	K	V	.	.	.	Q	D	L	Q	V	V	G
Query Conservation																																						.	.																																	.	.	.
Alig confidence		.	.	.	.	.	.	.																														.	.																																	.	.	.
Template Conservation		.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	I	P	K	V	F	A	K	L	L	Y	G	F	H	A	L	K	S	R	G	Q	Q	G	I	G	I	S	A	A	V	L	Y	A	Q	M	T	A	G	R	H	T	K	I	L	S	K	T	S	P	T	A	P	A	H	Y	Y	E	L	M	I	N	T	S	T	N	E	P	D	I	L	V	D	E	V
Template Known Secondary structure		.	.	.	.	.	.	.						S													S	S	S	S														T											S	S	S	S											S	S	S		S
Template Predicted Secondary structure		.	.	.	.	.	.	.
Template SS confidence
									90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.
Predicted Secondary structure																																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		T	C	G	K	R	N	T	G	T	S	V	H	F	W	P	D	E	T	F	F	D	S	P	R	F	S	V	S	R	L	T	H	V	L	K	A	K	A	V	L	C	P	G	V	E	I	T	F	K	D	E	I	N	N	T	E	Q	R	W	C	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																												.	.	.																							.									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																												.	.	.																							.
Template Sequence		R	D	W	F	R	P	H	G	T	Q	I	E	L	E	M	R	A	A	Y	V	K	G	R	R	Q	S	.	.	.	I	Y	E	Y	L	K	A	T	A	I	V	N	P	H	A	R	I	T	L	I	D	P	.	D	G	N	E	E	V	F	E	R	A	T	D	K	M	P	E	P	A	E	E	I	L	P	H	P	E	G	I
Template Known Secondary structure					S		S	S									S							S	S	S	S	.	.	.	S													S								T	.	T	S																							S	T	T
Template Predicted Secondary structure																												.	.	.																							.
Template SS confidence
		166	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.				.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.		.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
																						215	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	Q	D	G	L	N	D	Y	L	A	E	A	V	N	G	L	P	T	L	P	E	K	P	F	I	G	N	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	L	G	T	L	M	K	M	L	H	Y	T	E	P	F	L	R	Y	S	F	C	K	L	L	T	A	E	E	I	C	K	A	A	G	L	D	P	E	I	D	P	H	A	L	G	R	H	E	A	R	K	L	I	E	A	F	E	K	V	K	I	M	A	P	P	T	D	C	L	S	P	I	G	E	D	L	I	Y	R	G
Template Known Secondary structure																T	T	S	S	S	S												T	T	T			T	T	S		S	S	S			S	S	S	S	T	T	T	T					T	S			S				S	T	T
Template Predicted Secondary structure
Template SS confidence
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.
																					242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.				260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	F	A	G	D	T	E	A	V	D	W	A	L	L	W	L	P	E	G	.	.	.	G	E	L	L	T	E	S	Y	V	N	L	I	P	T	M	Q	G	G	T	H	V	N	G	L	R	Q	G	L	L	D	A	M	R	E	F	C	E	Y	R	N
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.																.	.	.	.	.	.	.	.	.
Template Conservation																																																									.	.	.	.	.	.	.	.	.
Template Sequence		L	E	K	E	T	T	V	D	F	I	A	T	S	T	R	K	P	A	V	Y	S	G	N	P	F	V	V	E	V	G	M	A	Y	G	G	N	L	P	K	E	E	K	I	S	I	M	R	F	A	N	R	V	P	L	L	.	.	.	.	.	.	.	.	.	Y	Q	Q	G	G	C	V	T	T	H	A	V	E	D	I	K
Template Known Secondary structure						S			S						B							T	T												S	S	S	S		S	S	S									T	T	B				.	.	.	.	.	.	.	.	.	S			T	T										S
Template Predicted Secondary structure																																																									.	.	.	.	.	.	.	.	.
Template SS confidence
		329	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.										.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.
		300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.		.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
Predicted Secondary structure																		.
Query SS confidence																		.
Query Sequence		I	L	P	R	G	V	K	L	S	A	E	D	I	W	D	R	.	C	A	Y	V	L	S	V	K	M	Q	D	P	Q	F	A	G	Q	T	K	E	R	L	S	S	R	Q	C	A	A	F	V	S	G	V	V	K	D	A	F	I	L	W	L	N	Q	N	V	Q	A	A	E	L	L	A	E	M	A	I	S	S	A	Q	R
Query Conservation																		.
Alig confidence																		.																									.	.	.														.	.	.	.	.	.	.
Template Conservation																																											.	.	.														.	.	.	.	.	.	.
Template Sequence		W	K	Q	Y	G	L	N	Q	P	G	G	G	I	P	V	G	P	V	I	L	L	I	H	V	A	S	I	N	V	P	F	T	S	E	S	K	D	A	I	A	D	.	.	.	I	P	V	I	K	E	E	I	D	L	A	I	K	.	.	.	.	.	.	.	E	V	A	R	K	L	K	H	Y	L	S	K	Q	S	N	L
Template Known Secondary structure			T	T	T	T					S	S	S	S			S	S										S	S			B	S	S	S	S	S	S	S	B			.	.	.														.	.	.	.	.	.	.
Template Predicted Secondary structure																																											.	.	.														.	.	.	.	.	.	.
Template SS confidence
		400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440				.	.	.	.	.	.	.	.	.	450	.	.	.								.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
		379	380	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	M	R	A	A	K	K	V	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	K	R	R	E	K	E	I	I
Template Known Secondary structure			T	T	T					T
Template Predicted Secondary structure
Template SS confidence
		470	.	.	.	.	.	.	.	.