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Job DescriptionP20083
Confidence100.00%DateThu Jan 5 11:37:45 GMT 2012
Rank2Aligned Residues343
% Identity17%Templatec1zxnB_
PDB info PDB header:isomeraseChain: B: PDB Molecule:dna topoisomerase ii, alpha isozyme; PDBTitle: human dna topoisomerase iia atpase/adp
Resolution2.51 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   7..10.........20.........30 .........40.........50 .........60
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Query Sequence  ADAIEVLTGLEPVRRRPGMYTDTT. . . . . . . . . . . . . . . . . . . . . . . . . RPNHLGQEVIDNSVDEALAG. HAKRVDVILH
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Template Sequence  ERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTID
Template Known Secondary structure  S




T


S
TTT
GGGT
TT

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   31........40.........50.........60.........70.........80.........90.........100.........110
 
   61. .......70.........80.........90.........100.........110.........120.........130. ......
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Query Sequence  AD. QSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVR. . RDGQVY
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Template Sequence  PENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMF
Template Known Secondary structure  TTTT
SS



STTTTSSS

S


GGG



S

SS
TGGGT
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   111........120.........130.........140.........150.........160.........170.........180.........190
 
   138.140.........150.........160.........170.........180.. .......190.........200.........210....
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Query Sequence  NIAFENGEKVQDLQVVGTCGKRNTGTSVHFWPDETFFDSPRFSVS. . . RLTHVLKAKAVLCPGVEITFKDEINNTEQRWC
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Template Sequence  KQTWMDNMGRAGEMELKPFNGE. DYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNK. . . . . . . L
Template Known Secondary structure  TTTT






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GGGGT
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SSS
TT.......
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   191........200.........210.. .......220.........230.........240.........250.........260. .
 
   215....220.........230.........240.........250.........260.........270.........280.........290....
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Query Sequence  YQDGLNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREF
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Template Sequence  PVKGFRSYVDMYLKK. . . . . . . . . . . . VIHEQVNHRWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDV
Template Known Secondary structure  S




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SSS
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B
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   263......270....... ..280.........290.........300.........310.........320.........330
 
   295....300.........310.........320.........330.........340.........350.........360.........370....
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Query Sequence  CEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAIS
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Template Sequence  VKKK. . . . . . . . . KAHQVKNHMWIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCG. . . . . IVESILN
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TT

SS

BSSTT

SB


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   341... .....350.........360.........370.........380.........390......... 400......
 
   375....380...
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Query Sequence  SAQRRMRAA
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Template Sequence  WVKFKAQVQ
Template Known Secondary structure  T

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   414.....420..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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