Job Description P52095 Confidence 99.87% Date Thu Jan 5 12:05:15 GMT 2012 Rank 30 Aligned Residues 292 % Identity 16% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		197	.	.	200	.	.	.	.	.	.	.	.	.	210	.		.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.				.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.					.	.	.	.	.	.	.					260	.	.	.	.
Predicted Secondary structure																	.																								.	.	.																			.	.	.	.								.	.	.	.
Query SS confidence																	.																								.	.	.																			.	.	.	.								.	.	.	.
Query Sequence		H	L	E	A	E	E	Y	I	A	R	T	F	G	A	E	.	Q	S	Y	I	V	T	N	G	T	S	T	S	N	K	I	V	G	M	Y	A	A	P	S	.	.	.	G	S	T	L	L	I	D	R	N	C	H	K	S	L	A	H	L	L	.	.	.	.	M	M	N	D	V	V	P	.	.	.	.	V	W	L	K	P
Query Conservation																	.																								.	.	.																			.	.	.	.								.	.	.	.
Alig confidence																	.																								.	.	.																			.	.	.	.								.	.	.	.
Template Conservation
Template Sequence		D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E	K	E	I	A	L	M	N	A	L	T	V	N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P
Template Known Secondary structure		T					G	G	G					T			G	G	G					S																		S	S	S							T	T																T	T
Template Predicted Secondary structure
Template SS confidence
		113	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.
		265	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.		.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.			.	.	.	330	.	.	.	.	.	.	.	.	.	340	.
Predicted Secondary structure																																												.																					.	.
Query SS confidence																																												.																					.	.
Query Sequence		T	R	N	A	L	G	I	L	G	G	I	P	R	R	E	F	T	R	D	S	I	E	E	K	V	A	A	T	T	Q	A	Q	W	P	V	H	A	V	I	T	N	S	.	T	Y	D	G	L	L	Y	N	T	D	W	I	K	Q	T	L	D	V	P	S	.	.	I	H	F	D	S	A	W	V	P	Y	T	H	F	H	P
Query Conservation																																												.																					.	.
Alig confidence									.	.	.	.	.	.	.	.	.																		.	.								.																					.	.												.	.	.	.
Template Conservation									.	.	.	.	.	.	.	.	.																		.	.																																										.	.	.	.
Template Sequence		R	E	G	E	E	T	L	.	.	.	.	.	.	.	.	.	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	.	.	V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	.	.	.	.
Template Known Secondary structure			T	T		S	S		.	.	.	.	.	.	.	.	.													G	G	G			.	.						S	B		T	T	T		B	B													T	T								T	T	T	T	T	T	.	.	.	.
Template Predicted Secondary structure									.	.	.	.	.	.	.	.	.																		.	.																																										.	.	.	.
Template SS confidence
		193	.	.	.	.	.	.										200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.			.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.
		342	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370		.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.																								.	.	390	.	.	.	.	.	.	.
Predicted Secondary structure																															.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																															.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		I	Y	Q	G	K	S	G	M	S	G	E	R	V	A	G	K	V	I	F	E	T	Q	S	T	H	K	M	L	A	.	A	L	S	Q	A	S	L	I	H	I	K	G	E	Y	D	E	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	F	N	E	A	F	M	M	H	T
Query Conservation																															.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.																							.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	V	E	L	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R
Template Known Secondary structure		.	.	.	.	.	.	.	S								T								S	S	S	T	T				T	T									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G
Template Predicted Secondary structure		.	.	.	.	.	.	.
Template SS confidence
									258	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330
		398	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	T	S	P	S	Y	P	I	V	A	S	V	E	T	A	A	A	M	L	R	G	N	P	G	K	R	L	I	N	R	S	V	E	R	A	L	H	F	R	K	E	V	Q	R	L	R	E	E	S	D	G	W	F	F	D	I	W	Q	P	P	Q	V	D	E	A	E	C	W	P	V	A	P	G	E	Q	W	H	G	F	N
Query Conservation
Alig confidence																																																.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	.	.	.	.	.	G	V	V	N	I	I	T	P	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure			S																																													.	.	.	.	.							S		S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		331	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.						.	.	.	380	.	.	.	.	.
		478	.	480	.	.	.	.	.	.	.	.	.	490					.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.		.	.	540	.	.	.	.	.	.	.	.	.	550	.	.
Predicted Secondary structure															.	.	.	.																																																.
Query SS confidence															.	.	.	.																																																.
Query Sequence		D	A	D	A	D	H	M	F	L	D	P	V	K	.	.	.	.	V	T	I	L	T	P	G	M	D	E	Q	G	N	M	S	E	E	G	I	P	A	A	L	V	A	K	F	L	D	E	R	G	I	V	V	E	K	T	G	P	Y	N	L	L	F	L	F	.	S	I	G	I	D	K	T	K	A	M	G	L	L	R	G
Query Conservation															.	.	.	.																																																.
Alig confidence		.	.	.	.	.	.	.	.	.					.	.	.	.												.	.	.	.	.	.	.	.	.	.	.	.																									.
Template Conservation		.	.	.	.	.	.	.	.	.																				.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	N	K	D	.	.	.	.	.	.	.	.	.	.	.	.	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F	H	D	V	Y	K	F	T	N	L
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	S	G	G	G	B		S									T	T			.	.	.	.	.	.	.	.	.	.	.	.							T	T	T							T	T	T					B			T	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.																				.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
											395	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.													.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.
		553	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	T	E	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	T	S	I
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		454	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions