|   |
198 | . | 200 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | |
|
|
|
. | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | A | E | E | Y | I | A | R | T | F | G | . |
. |
. |
. |
. |
. |
. |
A | E | Q | S | Y | I | V | T | N | G | T | S | T | S | N | K | I | V | G | M | Y | A | A | P | S | G | S | T | . |
. |
. |
. |
L | L | I | D | R | N | C | H | K | S | L | A | H | L | L | M | M | N | D | V | V | P | V | W | L | K | P | T | R |
Query Conservation |   |
  |
|
|
|   |
|
|
|   |   |
|
| . | . | . | . | . | . | . |
|   |   |
|   |
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |
|
|   | . | . | . | . |
|
|
|   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|   |
|
|
|
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
P | E | L | E | D | A | I | K | D | L | H | G | V | V | G | N | A | A | T | E | D | R | Y | I | V | V | G | T | G | S | T | Q | L | C | Q | A | A | V | H | A | L | S | S | L | A | R | S | Q | P | V | S | V | V | A | A | A | P | F | Y | S | T | Y | V | E | E | T | T | Y | V | R | S | G | M | Y | K | W | E | G | D | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | B |
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S | S |  |  |  |  |  |
| S | S |
|
|  |  |  |  |  |  |  |  | T | T |
|
| T | T |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 |
  |
  |   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
. | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | A | L | G | I | L | G | G | I | P | R | R | E | F | T | R | D | S | I | E | E | K | V | A | A | T | T | Q | A | Q | W | P | V | H | A | V | I | T | N | S | . |
T | Y | D | G | L | L | Y | N | T | D | W | I | K | Q | T | L | D | V | P | S | I | H | F | D | S | A | W | V | P | Y | T | H | F | H | P | I | Y | Q | G |
Query Conservation |   |
|   |   |
|   |   |
|   |
|   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |   |
|   |
|
|   |   |   |   |
|
|
|
|
|
| . |
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|   |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|
|   |
|   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|
|   |
|   |   | . |   |   |   |   |   |   | . | . | . |
Template Sequence |   |
W | G | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | K | K | G | P | Y | I | E | L | V | T | S | P | N | N | P | D | G | T | I | R | E | . |
. |
. |
. |
. |
. |
. |
T | V | V | A | K | V | I | H | D | F | A | Y | Y | W | . |
P | H | Y | T | P | I | . |
. |
. |
Template Known Secondary structure |   |
T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| S | S |
|  |  |  |  |  |  | S | S |
| T | T | T |
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
| T | T |
| S | . | T | T | T | S |
|
| . | . | . |
Template Predicted Secondary structure |   |
 |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|
|
|
|
| . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
151 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
190 | . | . | . | . | . | |
|
|
  |
  |   |
346 | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | |
. | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | |
|
|
|
. | 420 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
Query Sequence |   |
K | S | G | M | S | G | E | R | V | A | G | K | V | I | F | E | T | Q | S | T | H | K | M | L | A | . |
A | L | S | Q | A | S | L | I | H | I | K | G | E | Y | D | E | E | A | F | N | E | A | F | M | M | H | T | T | T | S | P | S | Y | P | I | V | A | S | V | E | T | A | A | A | M | L | R | G | . |
. |
. |
. |
N | P |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   | . | . | . | . |
|   |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |
|   |   |   |
|
|
|
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
T | R | R | Q | D | H | D | I | M | L | F | T | F | S | K | I | T | G | H | A | G | S | R | I | G | W | A | L | V | K | D | K | E | V | A | K | K | M | V | E | Y | I | I | V | N | S | I | G | V | S | K | E | S | Q | V | R | T | A | K | I | L | N | V | L | K | E | T | C | K | S | E | S | E |
Template Known Secondary structure |   |
. | . | . | . | . | . | . |
| S |
| B |
|
| S |  |  |  |  |  |  |  |  |  |  |
|
| G | G | G |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| S | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . |
  |
  |   |
421 | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | R | L | I | N | R | S | V | E | R | A | L | H | F | R | K | E | V | Q | R | L | R | E | E | S | D | G | W | F | F | D | I | W | Q | P | P | Q | V | D | E | A | E | C | W | P | V | A | P | G | E | Q | W | H | G | F | N | D | A | D | A | D | H | M | F | L | D | P | V | K | V | T | I | L | T | P | G | M | D | E |
Query Conservation |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |
Template Sequence |   |
S | E | N | F | F | K | Y | G | R | E | M | M | K | N | R | W | E | K | L | R | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | V | K | E | S | D | A | F | T | L | P | K | Y | P | E | A | F | C | N | Y | F | G | K | S | L | E | S | Y | P | A | F | A | W | L | G | T | K | E | E | T | D | . |
. |
Template Known Secondary structure |   |
T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  | T | S | S | S |  |  |
|
|
|
|
|
|  |  |  | T | T | T | T |  |  |  |
|
|
|
| S |  |  |  |  |  |  | S | S | S |
|
| . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
276 | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | |
|
  |
  |   |
501 | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | |
|
|
|
. | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  | . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | G | N | M | S | E | E | G | I | P | A | A | L | V | A | K | F | L | D | E | R | G | I | V | V | E | K | T | G | P | Y | N | L | L | . |
. |
. |
. |
F | L | F | S | I | G | I | D | K | T | K | A | M | G | L | L | R | G | L | T | E | F | K |
Query Conservation |   |
  |
|   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |
|   |   |   |   |
|
| . | . | . | . |   |
|   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|   |
|
|   |
|   |
|
|   |   |
|
| . |   |   |   |   |   |
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | S | E | L | R | R | H | K | V | M | S | R | A | G | E | R | C | G | . |
S | D | K | K | H | V | R | V | S | M | L | S | R | E | D | V | F | N | V | F | L | E | R | L | A | N | M | K |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  | T | T | T |  |  |
|  |  | T | G | G | G | T | . | S |
| T | T |  |  |  |  |  | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
| . |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
338 | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | |
. | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . |
  |