|   |
147 | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
|
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  | . | . | . |  |  |  |
|
|
|
|
|
|
|  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | K | V | A | I | I | G | A | G | P | A | G | L | A | C | A | D | V | L | T | R | N | G | . |
. |
V | K | A | V | V | F | D | R | H | P | E | I | G | G | L | . |
. |
. |
L | T | F | G | I | P | A | F | K | L | E | K | E | . |
. |
V | M | T | R | R | R | E | I | F | T | G | M | G | I | E | F | K | L | N | T | E | V |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |
| . | . |   |   |
|
|
|   |
|
|   |   |   |   |
|
|   | . | . | . |
|   |   |
|
|
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |   |
|   |
|   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|
Template Sequence |   |
K | K | I | L | I | I | G | G | V | A | G | G | A | S | A | A | A | R | A | R | R | L | S | E | T | A | E | I | I | X | F | E | R | G | E | Y | V | S | F | A | N | C | G | L | P | Y | H | I | S | G | E | I | A | Q | R | S | A | L | V | L | Q | T | P | E | S | F | K | A | R | F | N | V | E | V | R | V | K | H | E | V |
Template Known Secondary structure |   |
|  |  |  |  |  |
|
| S | T | T |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |
| S | S | S |
| S | S | B |
| G | G | G |  |  |  |  |  | T | S | S | S |
|
| G | G | G | G | B |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  | T | T |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
|
|
|
|
|
|
220 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
G | R | D | V | Q | L | D | D | L | L | . |
. |
. |
. |
. |
. |
S | D | Y | D | A | V | F | L | G | V | G | T | Y | Q | S | M | R | G | G | L | E | N | E | D | A | D | G | V | Y | A | A | L | P | F | L | I | A | N | T | K | Q | L | M | G | F | G | E | T | R | D | E | P | F | V | S | M | E | G |
Query Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . |   |   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
| . |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | A | I | D | R | A | A | K | L | V | T | V | R | R | L | L | D | G | S | E | Y | Q | E | S | Y | D | T | L | L | L | S | P | G | A | . |
A | P | I | V | P | P | I | P | G | V | D | N | P | L | T | H | S | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | N | I | P | D | X | D | R | I | L | Q | T | I | Q | X | N | N | V |
Template Known Secondary structure |   |
 |  |  |  | T | T | T | T |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |
| S |  |  |  |  |
|
|
|  | . |  |  |
|
|
|
|
| T | T |
|
| S | T | T |  |  |
|
| . | . | . | . | . | . | . | . | . | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | |
. | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . |
  |
  |   |
288 | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | |
|
|
|
. | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | R | V | V | V | L | G | G | G | D | T | A | M | D | C | V | R | T | S | V | R | Q | G | A | K | H | V | T | C | A | Y | R | R | D | E | E | N | M | P | G | S | R | R | E | . |
. |
. |
. |
V | K | N | A | R | E | E | G | V | E | F | K | F | N | V | Q | P | L | G | I | E | V | N | G | N | G | K | V | S | G | V | K |
Query Conservation |   |
  |   |
|
|
|
|
|
|
|   |   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
Template Conservation |   |
|   |
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |
|   | . |   |
|
|
|
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |
Template Sequence |   |
E | H | A | T | V | V | G | G | G | F | I | G | L | E | X | X | E | S | L | H | H | L | G | I | . |
K | T | T | L | L | E | L | A | D | Q | V | X | T | P | V | D | R | E | X | A | G | F | A | H | Q | A | I | R | D | Q | G | V | D | L | R | L | G | T | A | L | S | E | V | S | Y | Q | V | Q | T | H | . |
. |
. |
V | A |
Template Known Secondary structure |   |
S |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . |  |  |  |  |  |
| S | S | S | S | S |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |
| S |
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  | . | . | . |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | |
|
|
. | . |
  |
  |   |
364 | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | V | R | T | E | M | G | E | P | D | A | K | G | R | R | R | A | E | I | V | A | G | S | E | H | I | V | P | A | D | A | V | I | M | A | F | G | F | R | P | H | N | M | E | W | L | A | K | H | S | V | E | L | D | S | Q | G | R | I | I | A | P | E | G | S | D | N | A | F | Q | T | S | N | P | K | I | F | A | G | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |
|
|   |
|
|   |
|   |
|   |   |
|
|   |   | . |
|
|   |   |   |
|
|   |
|   |   |   |
|   |
|   |
| . | . | . | . |
|   |   |   |   |
|
|   |
|   |
|
|
|   |
|
Template Sequence |   |
S | D | A | A | G | E | D | T | A | H | Q | H | I | K | G | H | L | S | L | T | L | S | N | G | E | L | L | E | T | D | L | L | I | X | A | I | G | V | R | P | E | T | Q | . |
L | A | R | D | A | G | L | A | I | G | E | L | G | G | I | K | V | . |
. |
. |
. |
N | A | X | X | Q | T | S | D | P | A | I | Y | A | V | G |
Template Known Secondary structure |   |
| T | T | T | T |
|
|
| T | T |
|
| T | T |
|  |  |  |  |  |  | T | T | S |
|  |  |  |  | S |
|  |  |  |
| S |
|  |  |  |
|
|  | . |  |  |  |  | T | T |
|
| B |
| T | T | S | S | B |
|
| . | . | . | . |
| T | T |
| B |
| S | S | T | T |  |  |  |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  | . |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | |
. | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | |
|
|
|
. | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
  |
  |   |
444 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | I | V | R | G | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | L | V | V | T | A | I | A | E | G | R | K | A | A | D | G | I |
Query Conservation |   |
|   |
|   |
|   | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|
|   |   |
|   |
|
|
Template Sequence |   |
D | A | V | E | E | Q | D | F | V | T | G | Q | A | C | L | V | P | L | A | G | P | A | N | R | Q | G | R | X | A | A | D | N | X |
Template Known Secondary structure |   |
T | T | B |
|  |  | B | T | T | T |
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
  |