|   |
146 | . | . | |
|
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  | . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | K | . |
. |
V | A | I | I | G | A | G | P | A | G | L | A | C | A | D | V | L | T | R | N | G | V | K | A | V | V | F | D | R | H | P | E | I | G | G | L | L | T | F | G | I | P | A | F | . |
. |
. |
. |
. |
K | L | E | K | E | V | M | T | R | R | R | E | I | F | T | G | M | G | I | E | F | K | L | N | T | E |
Query Conservation |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|
|   |
|   |   |
|
|
|   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | E | K | F | D | V | I | I | V | G | L | G | P | A | A | Y | G | A | A | L | Y | S | A | R | Y | M | L | K | T | L | V | I | G | E | T | P | G | G | Q | L | T | E | A | G | I | V | D | D | Y | L | G | L | I | E | I | Q | A | S | D | M | I | K | V | F | N | K | H | I | E | K | Y | E | V | P | V | L | L | D | I | V |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S | S | T | T | G | G | G | G | G |
|
|  |  |
|
| S | T | T | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |
| S |
|  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
13 | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
  |
  |   |
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | G | R | D | V | Q | L | D | D | L | L | S | D | Y | D | A | V | F | L | G | V | G | T | Y | Q | S | M | R | G | G | L | E | N | E | D | A | D | G | V | Y | A | A | L | P | F | L | I | A | N | T | K | Q | L | M | G | F | G | E | T | R | D | E | P | F | V | S | M | E | G | K | R | V | V | V | L | G | G | G | D | T |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|   |   |
Alig confidence |   |
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
E | K | I | E | . |
. |
. |
. |
. |
. |
. |
N | R | G | D | E | F | V | V | K | T | K | R | K | G | E | F | K | A | D | S | V | I | L | G | I | G | V | K | R | R | K | L | G | V | P | G | E | Q | E | F | A | G | R | G | I | S | Y | C | S | V | C | D | A | P | L | F | K | N | R | V | V | A | V | I | G | G | G | D | S |
Template Known Secondary structure |   |
 |  |  |  | . | . | . | . | . | . | . |  |
| S | S | S |  |  |  |  |  | S | S | S |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
| T | T | T | T | T | T | B | T | T | T |  |  | S |
|  |  |  |  | G | G | G | G | T | T |
|  |  |  |  |  |
| S | S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
93 | . | . | . | |
|
|
|
|
|
|
. | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . |
  |
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | M | D | C | V | R | T | S | V | R | Q | G | A | K | H | V | T | C | A | Y | R | R | D | E | E | N | M | P | G | S | R | R | E | V | K | N | A | R | E | E | G | V | E | F | K | F | N | V | Q | P | L | G | I | E | V | N | G | N | G | K | V | S | G | V | K | M | V | R | T | E | M | G | E | P | D | A | K | G | R | R |
Query Conservation |   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
A | L | E | G | A | E | I | L | S | S | Y | S | T | . |
. |
K | V | Y | L | I | H | R | R | D | T | F | K | A | Q | P | I | Y | V | E | T | V | K | K | K | P | N | V | E | F | V | L | N | S | V | V | K | E | I | K | G | D | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T | T |
| S | . | . |  |  |  |  |  |  | S | S | S | S |
|
| S |
|  |  |  |  |  |  |  |  | T |
| T | T |  |  |  |  |  | S |  |  |  |  |  |  |  |  | S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
166 | . | . | . | 170 | . | . | . | . | . | . | . | . | |
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
379 | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | |
|
|
. | . | 450 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | E | I | V | A | G | S | E | H | I | V | P | A | D | A | V | I | M | A | F | G | F | R | P | H | N | M | E | W | L | A | K | H | S | V | E | L | D | S | Q | G | R | I | I | A | P | E | G | S | D | N | A | F | Q | T | S | N | P | K | I | F | A | G | G | D | I | V | R | . |
. |
. |
G | S | D | L | V | V | T | A |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|
|   |
|   | . | . | . |
|   |   |   |
|   |   |
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
| . | . | . | . |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
. |
. |
V | V | K | Q | V | V | V | E | N | L | K | V | N | G | V | F | I | E | I | G | F | D | P | P | . |
T | D | F | A | K | S | N | G | I | E | T | D | T | N | G | Y | I | K | V | . |
. |
. |
. |
D | E | W | M | R | T | S | V | P | G | V | F | A | A | G | D | C | T | S | A | W | L | G | F | R | Q | V | I | T | A |
Template Known Secondary structure |   |
. | . | S |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |
|
| . |  |  |  |  |  |  | T | T |
|
| B |
| T | T | S | S | B |
|
| . | . | . | . |
| T | T |
| B |
| S | S | T | T |  |  |  |
| S | T | T | B | S | T | T | T | T |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . |
|
|
|  |  |  |
|
|
|  |  |
|
|
|
|
|  |  |  | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | |
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | |
|
|
|
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
  |
  |   |
456 | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | A | E | G | R | K | A | A | D | G | I | M | N | W | L | E |
Query Conservation |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
Template Sequence |   |
V | A | Q | G | A | V | A | A | T | S | A | Y | R | Y | V | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
302 | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
  |