Job Description P09832 Confidence 100.00% Date Thu Jan 5 11:02:29 GMT 2012 Rank 1 Aligned Residues 458 % Identity 27% Template c1gthD_ PDB info PDB header:oxidoreductase Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil Resolution 2.25 Å

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		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.			.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.
Predicted Secondary structure																																	.	.
Query SS confidence																																	.	.
Query Sequence		N	V	Y	Q	F	I	D	L	Q	R	V	D	P	P	K	K	P	L	K	I	R	K	I	E	F	V	E	I	Y	E	P	.	.	F	S	E	G	Q	A	K	A	Q	A	D	R	C	L	S	C	G	N	P	Y	C	E	W	K	C	P	V	H	N	Y	I	P	N	W	L	K	L	A	N	E	G	R	I	F	E	A	A
Query Conservation																																	.	.
Alig confidence																																	.	.
Template Conservation
Template Sequence		K	K	L	D	K	K	H	W	K	R	N	P	D	K	N	C	F	H	C	E	K	L	E	N	N	F	D	D	I	K	H	T	T	L	G	E	R	G	A	L	R	E	A	M	R	C	L	K	C	A	D	A	P	C	Q	K	S	C	P	T	H	L	D	I	K	S	F	I	T	S	I	S	N	K	N	Y	Y	G	A	A
Template Known Secondary structure												S			T	T								T	T							T	T																		T	T						T	S	T	T													T	T
Template Predicted Secondary structure
Template SS confidence
		34	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.		.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.									.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.
Predicted Secondary structure																																				.																					.	.	.	.	.	.	.	.
Query SS confidence																																				.																					.	.	.	.	.	.	.	.
Query Sequence		E	L	S	H	Q	T	N	T	L	P	E	V	C	G	R	V	C	P	Q	D	R	L	C	E	G	S	C	T	L	N	D	E	F	G	.	A	V	T	I	G	N	I	E	R	Y	I	N	D	K	A	F	E	M	G	W	.	.	.	.	.	.	.	.	R	P	D	M	S	G	V	K	Q	T	G	K	K	V	A	I	I
Query Conservation																																				.																					.	.	.	.	.	.	.	.
Alig confidence																																				.																					.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		K	M	I	F	S	D	N	P	L	G	L	T	C	G	M	V	C	P	T	S	D	L	C	V	G	G	C	N	L	Y	A	T	E	E	G	S	I	N	I	G	G	L	Q	Q	F	A	S	E	V	F	K	A	M	N	I	P	Q	I	R	N	P	C	L	P	S	Q	E	K	M	P	E	A	Y	S	A	K	I	A	L	L
Template Known Secondary structure									T	T										G	G	G	S	G	G	G	G		G	G	G	G	S	T	T																				T				B			T	T	S			G	G	G	S		G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		114	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.
		153	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.		.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.		.	.	.	.	.	.	.	.	230
Predicted Secondary structure																					.																																																			.
Query SS confidence																					.																																																			.
Query Sequence		G	A	G	P	A	G	L	A	C	A	D	V	L	T	R	N	G	V	K	.	A	V	V	F	D	R	H	P	E	I	G	G	L	L	T	F	G	I	P	A	F	K	L	E	K	E	V	M	T	R	R	R	E	I	F	T	G	M	G	I	E	F	K	L	N	T	E	V	G	R	.	D	V	Q	L	D	D	L	L	S
Query Conservation																					.																																																			.
Alig confidence																					.																																																			.
Template Conservation
Template Sequence		G	A	G	P	A	S	I	S	C	A	S	F	L	A	R	L	G	Y	S	D	I	T	I	F	E	K	Q	E	Y	V	G	G	L	S	T	S	E	I	P	Q	F	R	L	P	Y	D	V	V	N	F	E	I	E	L	M	K	D	L	G	V	K	I	I	C	G	K	S	L	S	E	N	E	I	T	L	N	T	L	K	E
Template Known Secondary structure				S														T									S	S	S	S		S	T					T	S		T	T	T	S														T	T	T						S			B	S	T	T	S	B
Template Predicted Secondary structure
Template SS confidence
		194	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.
		231		.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.			.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
Predicted Secondary structure			.																						.	.
Query SS confidence			.																						.	.
Query Sequence		D	.	Y	D	A	V	F	L	G	V	G	T	Y	Q	S	M	R	G	G	L	E	N	E	.	.	D	A	D	G	V	Y	A	A	L	P	F	L	I	A	N	T	K	Q	L	M	G	F	G	E	T	R	D	E	P	F	V	S	M	E	G	K	R	V	V	V	L	G	G	G	D	T	A	M	D	C	V	R	T	S	V
Query Conservation			.																						.	.
Alig confidence			.																						.	.																		.
Template Conservation																																												.
Template Sequence		E	G	Y	K	A	A	F	I	G	I	G	L	P	E	P	K	T	D	D	I	F	Q	G	L	T	Q	D	Q	G	F	Y	T	S	K	D	F	L	P	L	V	A	K	.	S	S	K	A	G	M	C	A	C	H	S	P	L	P	S	I	R	G	A	V	I	V	L	G	A	G	D	T	A	F	D	C	A	T	S	A	L
Template Known Secondary structure		T	T																	G	G	G	T	T			T	T	T	T														.				T	T	T		S	S									S								S
Template Predicted Secondary structure																																												.
Template SS confidence
		274	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.		.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.
		308	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Q	G	A	K	H	V	T	C	A	Y	R	R	D	E	E	N	M	P	G	S	R	R	E	V	K	N	A	R	E	E	G	V	E	F	K	F	N	V	Q	P	L	G	I	E	V	N	G	N	G	K	V	S	G	V	K	M	V	R	T	E	M	G	E	P	D	A	K	G	R	R	R	A	E	I	V	A	G	S	E
Query Conservation
Alig confidence																																															.														.	.	.													.	.
Template Conservation																																															.														.	.	.													.	.
Template Sequence		R	C	G	A	R	R	V	F	L	V	F	R	K	G	F	V	N	I	R	A	V	P	E	E	V	E	L	A	K	E	E	K	C	E	F	L	P	F	L	S	P	R	K	V	I	.	V	K	G	G	R	I	V	A	V	Q	F	V	R	.	.	.	T	E	Q	D	E	T	G	K	W	N	E	D	.	.	E	D	Q	I
Template Known Secondary structure			T	T		S							S	S		G	G	G			S											T	T						S								.			S	S	S									.	.	.					S	S	S						.	.
Template Predicted Secondary structure																																															.														.	.	.													.	.
Template SS confidence
		353	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.		.	.	400	.	.	.	.	.	.	.	.	.	410				.	.	.	.	.	.	.	.	.	420	.	.			.	.	.	.
		388	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.		.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.
Predicted Secondary structure																							.
Query SS confidence																							.
Query Sequence		H	I	V	P	A	D	A	V	I	M	A	F	G	F	R	P	H	N	M	E	W	.	L	A	K	H	S	V	E	L	D	S	Q	G	R	I	I	A	P	E	G	S	D	N	A	F	Q	T	S	N	P	K	I	F	A	G	G	D	I	V	R	G	S	D	L	V	V	T	A	I	A	E	G	R	K	A	A	D	G	I
Query Conservation																							.
Alig confidence																							.																		.	.	.
Template Conservation																																									.	.	.
Template Sequence		V	H	L	K	A	D	V	V	I	S	A	F	G	S	V	L	R	D	P	K	V	K	E	A	L	S	P	I	K	F	N	R	W	D	L	P	E	V	D	.	.	.	P	E	T	M	Q	T	S	E	P	W	V	F	A	G	G	D	I	V	G	M	A	N	T	T	V	E	S	V	N	D	G	K	Q	A	S	W	Y	I
Template Known Secondary structure							S																		T	T	T	T	S		B		T	T	S	S	B				.	.	.	T	T	T		B		S	S	T	T					G	G	G	G	T				S
Template Predicted Secondary structure																																									.	.	.
Template SS confidence
		427	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.				.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.
		467	.	.	470	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	N	W	L	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	K	Y	I	Q
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		504	.	.	.	.