|   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | |
. | . | 70 | . | . | . | . | . | . | . | . | . | 80 | |
|
|
|
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|
|
|
|
|  | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
R | K | G | E | V | Q | I | G | L | W | L | S | S | T | T | A | Y | M | A | E | I | A | A | T | S | G | Y | D | W | L | . |
. |
. |
. |
. |
. |
. |
. |
L | I | D | G | E | H | A | P | N | T | I | Q | D | L | Y | H | Q | L | Q | A | V | A | P | Y | . |
A | S | Q | P | V | I | R | P | V | E | G | S | K | . |
. |
. |
. |
Query Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|   |
| . | . | . | . | . | . | . | . |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   | . |
|   |   |   |   |
|
|
|   |   |   |   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |
|
|   |   |
| . |   |
|   |
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|   |
|
|   |   |
Template Sequence |   |
P | D | G | K | K | V | . |
X | L | A | A | N | I | G | T | P | K | D | V | A | S | A | L | A | N | G | A | E | G | V | G | L | F | R | T | E | F | L | Y | X | D | R | N | S | L | P | S | E | E | E | Q | F | E | A | Y | K | E | V | V | E | K | X | G | G | R | P | V | T | I | R | T | L | D | I | G | G | D | K | E | L |
Template Known Secondary structure |   |
T | T | S |
| B |
| . |  |  |  |  |  |  | S | S | T | T |  |  |  |  |  |  |  | T | T |
| S | S |  |  |  |  |
|
| G | G | G | T | S | S | S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
|  |  |  |  |
|
|
|
| B | T | T | S |
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
264 | . | . | . | . | . | |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | L | I | K | Q | V | L | D | I | G | A | Q | T | L | L | I | P | M | V | D | T | A | E | Q | A | R | Q | V | V | S | A | T | R | Y | P | P | Y | G | E | R | G | V | G | A | S | V | A | R |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|
|   |
|
|   |
|
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |
|   |
|   |
|
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |
|   |
|
|   |
|
|   |
|
|
|
|   |   |
|   |   |
|   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |
|
|   |
|
|
|   |   |   |   |
|   |   |   |   |
|   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
P | Y | L | D | X | P | K | E | X | N | P | F | L | G | Y | R | A | I | R | L | C | L | D | R | P | D | I | F | K | T | Q | L | R | A | I | L | R | A | S | A | Y | G | N | V | Q | I | X | Y | P | X | I | S | S | V | E | E | V | R | K | A | N | S | I | L | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
G | G | G |
|
|
|
|
| S |
| G | G | G | S | S | B | T |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | S |
|  |  |  |  |  |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
343 | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
129 | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
|
|
|
. | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 190 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | R | W | G | R | I | E | N | Y | M | A | Q | V | . |
. |
. |
. |
N | D | S | L | C | L | L | V | Q | V | E | S | K | T | A | L | D | N | L | D | E | I | L | D | V | E | G | I | D | G | V | F | I | G | P | A | D | L | S | A | S | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Y | P | D | N | A | G | H | P | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . |
|   |   |   |   |
|   |   |
|
|
|
|   |   |
|
|   |   |
|   |
|
|   |
|   |
|
|
|
|   |
|   |
|
|   |   |
|
|
|   |
|
| . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|   | . | . |   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |
|   |   |
|
|   |   |   |
|   |   |   |
|
|
Template Sequence |   |
. |
. |
. |
. |
. |
E | V | K | A | E | L | D | R | E | G | V | K | Y | D | K | E | I | K | V | G | I | X | V | E | I | P | S | A | A | V | T | A | D | I | L | A | K | . |
. |
E | V | D | F | F | S | I | G | T | N | D | L | T | Q | Y | T | L | A | V | D | R | X | N | E | H | V | K | E | Y | Y | Q | P | F | H | P | A |
Template Known Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  |  | T | T |
|
|
|
| T | T |
|  |  |  |  |  |  |
| S |  |  |  |  |  | T |  |  |  |  |  | T | . | . | T |
| S |  |  |  |  |
|  |  |  |  |  |  |  |  | T | T |
|
| T | T |
| T | T | T | G | G | G |
|
| T | T | S |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
408 | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | |
|
. | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 |
  |
  |   |
195 | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
|
|
. | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | Q | R | I | I | E | T | S | I | R | R | I | R | A | A | G | K | A | A | G | F | L | . |
. |
. |
A | V | A | P | D | M | A | Q | Q | C | L | A | W | G | A | N | F | V | A | V | G | V | D | T | M | L | Y | S | D | A | L |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|
|
|
|
|
|   |
|   |
|
|   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|
|
|   |   |
|   |   |
|
|   |   |
Template Sequence |   |
I | L | R | L | V | K | X | V | I | D | A | A | H | K | E | G | K | F | A | A | X | C | G | E | X | A | G | D | P | L | A | A | V | I | L | L | G | L | G | L | D | E | F | S | X | S | A | T | S | I | P | E | I | K | N | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
| S | G | G | G | G |
| T | T | T |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
481 | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . |
  |