|   |
24 | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | V | N | V | E | V | L | Q | D | K | L | D | H | P | W | A | L | A | F | L | P | D | N | H | G | M | L | I | T | L | R | G | G | . |
. |
. |
. |
. |
. |
E | L | R | H | W | Q | A | G | K | G | L | S | A | P | L | S | G | V | P | D | V | W | A | H | G | Q | G | G | L | L | D | V | V | L | A | P | D | F | A | Q | S |
Query Conservation |   |
|   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
G | T | A | T | A | L | S | E | A | E | V | E | N | P | S | Y | L | V | P | S | A | D | G | K | F | I | Y | A | V | S | E | F | S | N | E | Q | A | A | A | N | A | F | A | F | N | K | E | E | G | T | F | R | L | L | N | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | K | T | G | G | E | D | P | C | Y | I | I | T | N |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
| S |
|
|
|
|  |  |  |
| S | S | S | S |  |  |  |  |  |  |
|
| S | S | T | T |
|  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |
| S | S | S |
|  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
61 | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 |
  |
  |   |
98 | . | |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | R | . |
I | W | L | S | Y | S | E | V | G | D | D | G | K | A | G | T | A | V | G | Y | G | R | L | S | D | D | L | S | K | V | T | D | F | R | T | V | F | R | Q | M | P | K | L | S | T | G | N | H | F | G | G | R | L | V | F | D | G | K | G | Y | L | F | I | A | L | G | E | N | N | Q | R | P | T | A | Q | D | L |
Query Conservation |   |
|   | . |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | S | N | V | V | T | A | N | Y | S | G | G | S | I | S | V | F | P | I | D | K | D | G | . |
. |
. |
. |
S | L | L | P | A | S | E | V | V | K | F | K | G | S | G | A | D | K | E | R | Q | E | K | P | H | L | H | C | V | R | I | T | P | D | G | K | Y | L | F | A | D | D | L | G | T | D | Q | I | H | K | F | I | V |
Template Known Secondary structure |   |
S | S |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  | B |
| T | T | S | . | . | . | . |
| B |
| S |
|
|  |  |  |  |
|
|
|
|
| S | S | T | T | T |
| S | S |
|
|  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | |
|
|
|
. | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . |
  |
  |   |
177 | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | K | L | Q | G | K | L | V | R | L | T | D | Q | G | E | I | P | D | D | N | P | F | I | K | E | S | G | A | R | A | E | I | W | S | Y | G | I | R | N | P | Q | G | M | A | M | N | P | W | S | N | A | L | W | L | N | E | H | G | P | R | G | G | D | E | I | N | I | P | Q | K | G | K | N | Y | G | W | P | L | A | T |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | P | N | A | K | A | D | N | E | D | V | F | L | K | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | S | P | A | S | Y | K | V | E | A | G | S | G | P | R | H | L | T | F | A | P | N | G | S | Y | A | Y | L | I | . |
. |
N | E | L | S | G | T | V | I | A | F | E | Y | N | D | G | E | L | K | E | I | Q | T | I |
Template Known Secondary structure |   |
| T | T |
|
| T | T | S |
|
|
| S |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  | . | . |  | T | T | T |
|  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
207 | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | |
|
. | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . |
  |
  |   |
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | G | I | N | Y | S | G | F | K | I | P | E | A | K | G | E | I | V | A | G | T | E | Q | P | V | F | Y | W | K | D | S | P | A | V | S | G | M | A | F | Y | N | S | D | K | F | P | Q | W | Q | Q | K | L | F | I | G | A | L | K | D | K | D | V | I | V | M | S | V | N | G | D | K | V | T | E | D | G | R | I | L | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
A | A | D | T | V | G | A | K | G | S | G | D | I | H | I | S | P | D | G | K | F | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | A | S | N | R | L | K | A | D | G | L | A | I | F | S | I | H | P | E | N | G | X | L | T | K | V | G | Y | Q |
Template Known Secondary structure |   |
 | S |
| S | S |
|
|
|
|  |  |  |  |  |  |
| T | T | S | S |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |
| T | T | T |
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
274 | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . |
  |
  |   |
337 | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | |
|
. | . | . | . | . | . | . | 370 | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | R | G | Q | R | I | R | D | V | R | T | G | P | D | G | Y | L | Y | V | L | T | D | E | S | S | G | . |
. |
E | L | L | K | V | S | P | R | N |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |
| . | . |   |
|   |
|
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|
Template Sequence |   |
L | T | G | I | H | P | R | N | F | I | I | T | P | N | G | K | Y | L | L | V | A | C | R | D | S | N | V | I | Q | V | Y | E | R | D | T | D | T |
Template Known Secondary structure |   |
 |
| S | S |
|  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |
| T | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
325 | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . |
  |