|   |
23 | . | . | . | . | . | . | 30 | . | . | . | |
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
| . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | T | V | N | V | E | V | L | Q | D | K | . |
. |
L | D | H | P | W | A | L | A | F | L | P | D | N | H | G | M | L | I | T | L | R | G | G | E | L | R | H | W | Q | A | G | K | G | L | S | A | P | L | S | G | V | P | D | V | W | A | H | G | Q | G | G | L | L | D | V | V | L | A | P | D | F | A | Q | S | R | R | I |
Query Conservation |   |
  |
|   |   |
|   |   |   |
|   |   | . | . |
|   |   |
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
Template Sequence |   |
M | N | F | Y | L | E | E | F | N | L | S | I | P | D | S | G | P | Y | G | I | T | S | S | E | D | G | K | V | W | F | T | Q | H | K | A | N | K | I | S | S | L | D | Q | S | G | R | I | K | E | F | E | V | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | P | D | A | K | V | M | C | L | I | V | S | S | L | G | D | I |
Template Known Secondary structure |   |
G | S |  |  |  |  |  |  |  |
| S | S | T | T |
|
|  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  | T | T | T | T |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
| S | . | . | . | . | . | . | . | . | . | . | S | T | T |
|
|  |  |  |  |  |  |
| T | T | S |
|  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 |
  |
  |   |
101 | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | L | S | Y | S | E | V | G | D | D | G | K | A | G | T | A | V | G | Y | G | R | L | S | D | D | L | S | K | V | T | D | F | R | T | V | F | R | Q | M | P | K | L | S | T | G | N | H | F | G | G | R | L | V | F | D | G | K | G | Y | L | F | I | A | L | G | E | N | N | Q | R | P | T | A | Q | D | L | D | K | L | Q |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
W | F | T | E | N | G | A | N | K | I | G | K | L | S | K | K | G | G | F | T | E | Y | P | L | P | Q | P | D | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | P | Y | G | I | T | E | G | L | N | G | D | I | W | F | T | Q | L | N | G | D | R | I | G | K | L | T | A | D | G | T | I | Y |
Template Known Secondary structure |   |
 |  |  |  | T | T | T | T |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
| S | S | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |
| S | T | T |
|  |  |  |  |  | T | T | T | T |  |  |  |  |  |
| T | T | S |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . |
  |
  |   |
181 | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | L | V | R | L | T | D | Q | G | E | I | P | D | D | N | P | F | I | K | E | S | G | A | R | A | E | I | W | S | Y | G | I | R | N | P | Q | G | M | A | M | N | P | W | S | N | A | L | W | L | N | E | H | G | P | R | G | G | D | E | I | N | I | P | Q | K | G | K | N | Y | G | W | P | L | A | T | W | G | I | N |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | Y | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | P | N | K | G | S | Y | P | A | F | I | T | L | G | S | D | N | A | L | W | F | T | E | . |
. |
N | Q | N | N | S | I | G | R | I | T | N | T | G | K | L | E | E | Y | P | L | P | T | N | A | A | A | P |
Template Known Secondary structure |   |
 |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S | S | T | T |
|
|  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  | . | . | T | T | T | T |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |
| S | S | T | T |
|
|  |
Template Predicted Secondary structure |   |
 |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
133 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | |
|
. | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . |
  |
  |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | S | G | F | K | I | P | E | A | K | G | E | I | V | A | G | T | E | Q | P | V | F | Y | W | K | D | S | P | A | V | S | G | M | A | F | Y | N | S | D | K | F | P | . |
. |
. |
. |
. |
Q | W | Q | Q | K | L | F | I | G | A | L | K | D | K | D | V | I | V | M | S | V | N | G | D | K | V | T | E | D | G | R | I | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   | . | . | . |   |   |   |
Template Sequence |   |
V | G | I | T | S | G | N | D | G | A | L | W | F | V | E | I | M | G | N | K | I | G | R | I | T | T | T | G | E | I | S | E | Y | D | I | P | T | P | N | A | R | P | H | A | I | T | A | G | K | N | S | E | I | W | F | T | E | W | G | A | N | Q | I | G | R | I | T | N | D | N | T | I | Q | E | . |
. |
. |
Y | Q | L |
Template Known Secondary structure |   |
 |  |  |  |  |
| T | T | S | S |  |  |  |  |  | T | T | T | T |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |
| S | S | T | T |
|
|  |  |  |  |  |  |
| S | T | T |
|  |  |  |  |  | T | T | T | T |  |  |  |  |  |
| T | T | S |
|  |  |  | . | . | . |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  | . | . | . |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
186 | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | |
|
|
260 | . | . |
  |
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | D | R | G | Q | R | I | R | D | V | R | T | G | P | D | G | Y | L | Y | V | L | T | D | E | S | S | G | E | L |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|   |
|
|
|
|   |   |   |   |
|   |   |   |
Template Sequence |   |
Q | T | E | N | A | E | P | H | G | I | T | F | G | K | D | G | S | V | W | F | A | L | K | C | K | I | G | K | L |
Template Known Secondary structure |   |
| S | T | T |
|
|
|
|
|  |  |  |
| T | T | S |
|  |  |  |  |
| S | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . |
  |