Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	A	F	T	W	I	A	L	R	F	I	H	F	T	S	L	M	L	V	F	G	F	A	M	Y	G	A	W	L	A	P	L	T	I	R	R	L	L	A	K	R	F	L	R	L	Q	Q	H	A	A	V	W	S	L	I	S	A	T	A
Secondary structure
SS confidence
Disorder		?	?	?																														?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	L	A	V	Q	G	G	L	M	G	T	G	W	T	D	V	F	S	P	N	I	W	Q	A	V	L	Q	T	Q	F	G	G	I	W	L	W	Q	I	V	L	A	L	V	T	L	I	V	A	L	M	Q	P	R	N	M	P	R	L	L	F
Secondary structure
SS confidence
Disorder										?	?	?	?				?																																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	L	T	T	A	Q	F	I	L	L	A	G	V	G	H	A	T	L	N	E	G	V	T	A	K	I	H	Q	T	N	H	A	I	H	L	I	C	A	A	A	W	F	G	G	L	L	P	V	L	W	C	M	Q	L	I	K	G	R	W	R
Secondary structure
SS confidence
Disorder														?	?						?																																	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	Q	A	I	Q	A	L	M	R	F	S	W	C	G	H	F	A	V	I	G	V	L	A	S	G	V	L	N	A	L	L	I	T	G	F	P	P	T	L	T	T	Y	W	G	Q	L	L	L	L	K	A	I	L	V	M	I	M	V	V	I
Secondary structure
SS confidence
Disorder																																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
Sequence		A	L	A	N	R	Y	V	L	V	P	R	M	R	Q	D	E	D	R	A	A	P	W	F	V	W	M	T	K	L	E	W	A	I	G	A	V	V	L	V	I	I	S	L	L	A	T	L	E	P	F
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?	?																									?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1q90 chain G Region: 201 - 227 Aligned: 27 Modelled: 27 Confidence: 11.5% Identity: 22% Fold: Single transmembrane helix Superfamily: PetG subunit of the cytochrome b6f complex Family: PetG subunit of the cytochrome b6f complex Phyre2 PDB 1q90 chain G Region: 201 - 227 Aligned: 27 Modelled: 27 Confidence: 11.5% Identity: 22% PDB header:photosynthesis Chain: G: PDB Molecule:cytochrome b6f complex subunit petg; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii Phyre2 PDB 2iub chain A domain 2 Region: 185 - 247 Aligned: 47 Modelled: 47 Confidence: 10.6% Identity: 11% Fold: Transmembrane helix hairpin Superfamily: Magnesium transport protein CorA, transmembrane region Family: Magnesium transport protein CorA, transmembrane region Phyre2 PDB 3mk7 chain K Region: 11 - 281 Aligned: 268 Modelled: 271 Confidence: 9.5% Identity: 9% PDB header:oxidoreductase Chain: K: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit n; PDBTitle: the structure of cbb3 cytochrome oxidase Phyre2 PDB 2bbj chain B Region: 185 - 247 Aligned: 54 Modelled: 63 Confidence: 6.9% Identity: 11% PDB header:metal transport/membrane protein Chain: B: PDB Molecule:divalent cation transport-related protein; PDBTitle: crystal structure of the cora mg2+ transporter Phyre2 PDB 1i7w chain B Region: 188 - 194 Aligned: 7 Modelled: 7 Confidence: 5.9% Identity: 29% PDB header:cell adhesion Chain: B: PDB Molecule:epithelial-cadherin; PDBTitle: beta-catenin/phosphorylated e-cadherin complex Phyre2 1 d1q90g_ 2 c1q90G_ 3 d2iuba2 4 c3mk7K_ 5 c2bbjB_ 6 c1i7wB_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1q90g_ 11.5 22 Fold:Single transmembrane helix Superfamily:PetG subunit of the cytochrome b6f complex Family:PetG subunit of the cytochrome b6f complex 2 c1q90G_ 11.5 22 PDB header:photosynthesis Chain: G: PDB Molecule:cytochrome b6f complex subunit petg; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii 3 d2iuba2 10.6 11 Fold:Transmembrane helix hairpin Superfamily:Magnesium transport protein CorA, transmembrane region Family:Magnesium transport protein CorA, transmembrane region 4 c3mk7K_ 9.5 9 PDB header:oxidoreductase Chain: K: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit n; PDBTitle: the structure of cbb3 cytochrome oxidase 5 c2bbjB_ 6.9 11 PDB header:metal transport/membrane protein Chain: B: PDB Molecule:divalent cation transport-related protein; PDBTitle: crystal structure of the cora mg2+ transporter 6 c1i7wB_ 5.9 29 PDB header:cell adhesion Chain: B: PDB Molecule:epithelial-cadherin; PDBTitle: beta-catenin/phosphorylated e-cadherin complex

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0