|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
|
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | A | I | S | R | L | L | S | E | Q | L | G | E | G | E | I | E | L | R | N | E | L | P | G | G | E | . |
. |
V | H | A | A | W | H | L | R | Y | A | G | H | D | F | F | V | K | C | D | E | R | E | L | L | P | G | F | T | A | E | A | D | Q | L | E | L | L | S | R | S | K | T | V | T | V | P | K | V | W | A | V | G |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|
|   | . | . |   |
|   |
|
|   |
|   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |   |
|
|   | . |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
Template Sequence |   |
Q | Q | L | I | E | L | L | K | V | H | Y | G | I | . |
D | I | H | T | A | Q | F | I | Q | G | G | A | D | T | N | A | F | A | Y | Q | A | D | S | E | S | K | S | Y | F | I | K | L | K | Y | G | Y | H | D | . |
. |
. |
E | I | N | L | S | I | I | R | L | L | H | D | S | G | I | K | E | I | I | F | P | I | H | T | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  | S |
|
|
| S | S | S |
|  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |
|
| S | T |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S | S |
|
|
|
|
|
| T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
9 | 10 | . | . | . | . | . | . | . | . | . | 20 | . | |
. | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
|
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
81 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
|
. | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
A | D | . |
. |
. |
. |
. |
. |
R | D | Y | S | F | L | V | M | D | Y | L | P | P | R | P | L | . |
. |
. |
. |
. |
D | A | H | S | A | F | I | L | G | Q | Q | I | A | R | L | H | Q | W | S | D | Q | P | Q | F | G | L | D | F | D | N | A | L | S | T | T | P | Q | P | N | T | . |
. |
. |
. |
W | Q | R | R | W | S | T |
Query Conservation |   |
  |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | A | K | L | F | Q | Q | L | K | H | F | K | I | I | A | Y | P | F | I | H | A | P | N | G | F | T | Q | N | L | T | G | K | Q | W | K | Q | L | G | K | V | L | R | Q | I | H | E | T | S | V | P | I | S | I | Q | Q | Q | L | R | K | E | I | Y | S | P | K | W | R | E | I | V | R | S | F | Y | N | Q | I | E | F | D |
Template Known Secondary structure |   |
T | S |
| S | S |  |  |
| S | S | S |  |  |  |  |  |  |
|
|
|
|
| B | T | T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | T | T | S |  |  |
|
|
|
| S |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
. | . | . | . | 210 | . | . | |
. | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  | . |  |  |  |  |
|
|  | . |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | F | A | E | Q | R | I | G | W | Q | L | E | L | A | A | E | K | G | I | A | F | G | N | I | D | A | I | V | E | H | I | Q | Q | R | L | A | S | H | Q | P | Q | P | S | L | L | H | G | D | L | W | S | G | N | C | A | L | G | P | D | G | . |
P | Y | I | F | D | P | A | . |
C | Y | W | G | D | R | E | C | D | L | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |
|
|
|   |   |   |   |   | . |   |   |
|
|
|   |
| . |   |   |   |
|
|   |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
Template Sequence |   |
N | S | D | D | K | L | T | A | A | F | K | S | F | F | N | Q | N | S | A | A | I | H | R | L | V | D | T | S | E | K | L | S | K | K | I | Q | P | D | L | D | K | Y | V | L | C | H | S | D | I | H | A | G | N | V | L | V | G | N | E | E | S | I | Y | I | I | D | W | D | E | P | M | L | A | P | K | E | R | D | L | M |
Template Known Secondary structure |   |
S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| G | G | G |  |  |  |  |
| S |
|
| S | G | G | G |  |  |  |
| S | S | S |
|  |  |  |
|
|
| S |
|
|  |  |  |  | T |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
  |
  |   |
224 | . | . | . | . | . | |
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | L | P | L | H | T | . |
. |
. |
E | Q | P | P | Q | I | Y | D | G | Y | Q | S | V | S | P | L | P | A | D | F | L | E | R | Q | P | V | Y | Q | L | Y | T | L | L | N | R | A | R | L | F | G | G | Q | H | L |
Query Conservation |   |
  |   |   |   |   |   | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
F | I | G | G | G | V | G | N | V | W | N | K | P | H | E | I | Q | Y | F | Y | E | G | Y | G | E | I | N | V | D | K | T | I | L | S | Y | Y | R | H | E | R | I | V | E | D | I | A | V | Y | G | Q | D | L | L |
Template Known Secondary structure |   |
T | T | T |
|
| G | G | G |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
  |