|   |
32 | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | T | P | L | I | E | Q | Q | K | I | P | G | M | A | V | A | V | . |
I | Y | Q | G | K | P | Y | Y | F | T | W | G | Y | A | D | I | A | K | K | Q | P | V | T | Q | Q | T | L | F | E | L | G | S | V | S | K | T | F | T | G | V | L | G | G | D | A | I | A | R | G | E | I | K | L | S | D | P | T | T | K | Y | W | P |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
| . |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|   |
|   |
|
|   |   |
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |
|   |
|
|
|   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|   |
| . | . | . |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | S | T | F | F | D | K | F | S | A | S | G | G | F | V | L | F | N | S | N | R | K | K | Y | T | I | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | R | K | E | S | T | S | R | F | A | P | A | S | T | Y | K | V | F | S | A | L | L | . |
. |
. |
A | L | E | S | G | I | I | T | K | N | D | S | H | M | T | W | D | G |
Template Known Secondary structure |   |
|  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  | S |
| B |
|
| G | G | G | G |  |  |  |  |  |  |  | . | . | . |  |  |  |  | T | S | S |
| S | S |
|
|
| B |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
363 | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | |
|
|
. | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . |
  |
  |   |
111 | . | . | . | . | . | |
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | T | A | K | Q | . |
. |
W | N | G | I | T | L | L | H | L | A | T | Y | T | A | G | G | L | P | L | Q | V | P | D | E | V | K | S | S | S | D | L | L | R | F | Y | Q | N | W | Q | P | A | W | A | P | G | T | Q | R | L | Y | A | N | S | S | I | G | L | F | G | A | L | A | V | K | P | S | G | L | S | F | E | Q |
Query Conservation |   |
  |   |   |   |   |   | . | . |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
|   |   |   |   |
|
|
|   |
|
|
|   |
|
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
Template Sequence |   |
T | Q | Y | P | Y | K | E | W | N | Q | D | Q | D | L | F | S | A | M | S | S | S | T | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | Y | F | Q | K | L | D | R | Q | I | G | E | D | H | L | R | H |
Template Known Secondary structure |   |
|
|
| S | S | T | T | T | S | S |
| B |
|  |  |  |  |  |  |  | T |
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . |
  |
  |   |
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | M | Q | T | R | V | F | Q | P | L | K | L | N | H | T | W | I | N | V | P | P | A | E | E | K | N | Y | A | W | G | Y | R | E | G | K | A | V | H | V | S | P | G | A | L | D | A | E | A | Y | G | V | K | S | T | I | E | D | M | A | R | W | V | Q | S | N | L | K | P | L | D | I | N | E | K | T | L | Q | Q | G | I |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   | . | . | . | . | . |   |
|   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |
|   |   |   |   |   |
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |
|
Template Sequence |   |
Y | L | K | S | . |
. |
. |
. |
. |
I | H | Y | G | N | E | D | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | V | P | A | D | Y | W | L | D | G | S | L | Q | I | S | P | L | E | Q | V | N | I | L | K | K | F | Y | D | N | E | F | D | F | K | Q | S | N | I | E | T | V |
Template Known Secondary structure |   |
 |  |  |  | . | . | . | . | . | T | T |
| T | T |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |
| T | T | T | T | T | T | S | S | S | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
470 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 480 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . |
  |
  |   |
269 | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | L | A | Q | S | R | Y | W | Q | T | G | D | M | Y | Q | G | L | G | W | E | M | L | D | W | P | V | N | P | D | S | I | I | N | G | S | D | N | K | I | A | L | A | A | R | P | V | K | A | I | T | P | P | T | P | A | V | R | A | S | W | V | H | K | T | G | A | T | G | G | F | G | S | Y | V | A | F | I | P | E | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |
Template Sequence |   |
K | D | S | I | R | L | E | E | S | N | G | R | V | L | S | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | T | G | T | S | V | I | N | G | E | L | H | A | G | W | F | I | G | Y | V | E | T | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
523 | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . |
  |
  |   |
349 | |
|
|
|
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . |
Predicted Secondary structure |   |
| . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | . |
. |
. |
. |
L | G | I | V | M | L | A | N | K | N | Y | P | N | P | A | R | V | D | A | A | W | Q | I | L | N | A | L |
Query Conservation |   |
  | . | . | . | . |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
Alig confidence |   |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |   |   |
|
Template Sequence |   |
D | N | T | F | F | F | A | V | H | I | Q | G | E | K | R | A | A | G | S | S | A | A | E | I | A | L | S | I | L | D | K | K |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  |  | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
562 | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . |
  |