|   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | P | Q | Q | I | N | D | I | V | H | R | T | I | T | P | L | I | E | Q | Q | K | I | P | G | M | A | V | A | V | I | Y | Q | G | K | P | Y | Y | F | T | W | G | Y | A | D | I | A | K | K | Q | P | V | T | Q | Q | T | L | F | E | L | G | S | V | S | K | T | F | T | G | V | L | G | G | D | A | I | A | R | G | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |
|   |
Template Sequence |   |
S | N | A | L | L | T | S | Q | I | V | D | Q | Y | A | E | H | I | F | Y | N | S | G | A | V | G | X | A | L | V | V | I | D | N | N | Q | V | V | N | R | S | F | G | E | T | Q | P | G | N | N | I | R | P | R | P | D | S | L | I | R | I | A | S | I | T | K | L | X | T | S | E | I | X | V | K | L | A | D | D | G | I |
Template Known Secondary structure |   |
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
| S | S | T | T |
|
|
|
|
|
| T | T |
| B |  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
36 | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . |
  |
  |   |
99 | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
|
|
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | K | L | S | D | P | T | T | K | Y | W | P | E | L | T | A | . |
. |
. |
. |
K | Q | W | N | G | I | T | L | L | H | L | A | T | Y | T | A | G | G | L | P | L | . |
. |
. |
. |
. |
. |
. |
Q | V | P | D | E | V | K | S | S | S | D | L | L | R | F | Y | Q | N | W | Q | P | A | W | A | P | G | T | Q | R | L | Y | A |
Query Conservation |   |
|   |
|
|   |   |
|   |   |
|
|
|   |   |   |   | . | . | . | . |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
Template Sequence |   |
V | K | L | T | D | P | L | K | K | Y | A | P | K | G | V | N | V | P | S | Y | S | A | K | Q | P | I | R | L | L | H | L | A | S | H | T | S | G | L | P | R | E | Q | P | G | G | P | Q | K | R | P | V | F | T | W | P | T | K | D | N | R | W | Q | W | L | K | L | A | K | V | T | V | P | P | G | V | K | A | A | Y | S |
Template Known Secondary structure |   |
|
| T | T |
| B | G | G | G | G | S |
| T | T |
|
|
|
|
| S | S | T | T |
|
|
| B |  |  |  |  |  | T | T |
| S |
|
|
| S | S |
| S | S |
|
| S | S |
|
| T | T |
|
| S |
|  |  |  |  |  |  |  |  | T | T |
|
|
|
| S |
| T | T | S |  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
116 | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . |
  |
  |   |
168 | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | S | S | I | G | L | F | G | A | L | A | V | K | P | S | G | L | S | F | E | Q | A | M | Q | T | R | V | F | Q | P | L | K | L | N | H | T | W | I | N | V | P | P | A | E | E | K | N | Y | A | W | G | Y | R | E | G | K | A | V | H | V | S | P | G | A | L | D | A | E | A | Y | G | V | K | S | T | I | E | D | M | A |
Query Conservation |   |
|   |   |   |   |
|
|
|   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|
|
|   |
|
|
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |
|
|   |
Template Sequence |   |
N | L | A | Y | D | L | L | A | D | A | L | S | R | A | A | G | K | P | Y | A | H | L | L | R | D | K | I | T | A | P | L | G | X | K | N | T | T | L | T | P | T | A | E | Q | C | K | R | L | X | I | G | V | G | S | S | R | C | . |
. |
. |
G | N | T | V | A | A | A | G | S | G | G | I | Y | S | T | P | E | D | X | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  |  | T |  |  |  |  | T |
| T | T |
| B | S | S |
|
|  |  |  |  | T | T | B |
|
|
| T | T |
|
|
|
| . | . | . |
|
|
| G | G | G | T | T | T | T |
|
|  |  |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
196 | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
|
|
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
  |
  |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | W | V | Q | S | N | L | K | P | L | D | I | N | E | K | T | L | Q | Q | G | I | Q | L | A | Q | S | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | W | Q | T | G | D | M | Y | Q | G | L | G | W | E | M | L | D | W | P | V | N | P | D | S | I | I | N | G | S | D | N | K | I | A | L | A | A | R | P | V | K | A | I |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
H | W | X | Q | Q | F | L | A | S | D | N | S | A | P | K | R | S | A | K | R | E | Q | A | L | Y | F | Q | R | G | D | L | V | S | L | K | G | X | D | V | A | G | Q | A | D | A | L | G | L | G | W | V | Y | X | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  | T | T | S |
| B | T | T | B |
|
|
| T | T |  |  |  |  | T |
|  |  |  |  | G | G | G | S | S |  |  |  | S |
|
| T | T | S |
|
| S |  |  |  | S | S |
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
273 | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | |
|
. | . | . | . | . | . | . | 370 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | P | P | T | P | A | V | R | A | S | W | V | H | K | T | G | A | T | G | G | F | G | S | Y | V | A | F | I | P | E | K | E | L | G | I | V | M | L | A | N | K | N | Y | P | N | . |
. |
P | A | R | V | D | A | A | W | Q | I | L | N | A | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|   |
|   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
Template Sequence |   |
. |
. |
. |
P | K | A | D | L | P | G | I | X | Q | K | T | G | G | G | G | G | F | I | T | Y | X | A | X | V | P | E | K | N | I | G | V | F | V | V | V | T | R | S | Q | L | T | K | F | S | N | X | S | D | G | V | N | Q | L | V | A | E | L |
Template Known Secondary structure |   |
. | . | . |
| B | T | T | B |
|
|  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | G | G | G | T |  |  |  |  |  |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
327 | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . |
  |