|   |
40 | . | . | . | . | . | . | . | . | . | 50 | |
|
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 110 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
K | I | P | G | M | A | V | A | V | I | Y | . |
. |
Q | G | K | P | Y | Y | F | T | W | G | Y | A | D | I | A | K | K | Q | P | V | T | Q | Q | T | L | F | E | L | G | S | V | S | K | T | F | T | G | V | L | G | G | D | A | I | A | R | G | E | I | K | L | S | D | P | T | . |
. |
. |
. |
. |
. |
. |
T | K | Y | W | P |
Query Conservation |   |
  |   |
|
|   |
|
|   |
|   |   | . | . |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|   |
|   |
|
|   |   |
| . | . | . | . | . | . | . |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|
|
|   |   |
|   |   |
|
|   |
|
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |
|   |   |
|   |
|   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | I | T | A | Q | T | Y | V | L | M | D | Y | N | S | G | A | I | L | T | A | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | P | D | Q | R | Q | Y | P | A | S | L | T | K | M | M | T | S | Y | V | V | G | V | A | L | K | Q | G | K | I | H | N | T | D | M | V | T | I | G | E | S | A | W | G | R | N | F | P |
Template Known Secondary structure |   |
|
|
| S | S |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | S | T | T | S |
| B |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
| T | T |
|  |  |  |
|
| T | T | T |
| G | G | G |
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
35 | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . |
  |
  |   |
|
|
|
111 | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | |
|
|
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
E | L | T | A | K | Q | W | N | G | I | T | L | L | H | L | A | T | Y | T | . |
. |
. |
A | G | G | L | P | L | Q | V | P | D | E | V | K | S | S | S | D | L | L | R | F | Y | Q | N | W | Q | P | A | W | A | P | G | T | Q | R | L | Y | A | N | S | S | I | G | L | F | G | A | L | A | V | K | P | S | G | L |
Query Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
| . | . | . |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
|   |   |   |   |
|
|
|   |
|
|
|   |
|
|
|   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|   |   |
|
|   |   |
| . |
|
|
|   |   |
Template Sequence |   |
D | S | S | K | M | F | L | D | L | N | T | Q | V | S | V | A | D | L | N | R | G | V | I | V | V | S | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | D | A | T | V | A | L | A | E | H | I | . |
S | G | N | V | P |
Template Known Secondary structure |   |
T | S |
|
|
|
|
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | . |  | S | S |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
103 | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
130 | . | . | . | . | . | . | . | . | . | 140 | |
. | . | . | . | . |
  |
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | |
. | . | . | 260 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Query Sequence |   |
S | F | E | Q | A | M | Q | T | R | V | F | Q | P | L | K | L | N | H | T | W | I | N | V | P | P | A | E | E | K | N | Y | A | W | G | Y | R | E | G | K | A | V | H | V | S | P | G | A | L | D | A | E | A | Y | G | V | K | S | T | I | E | D | M | A | R | W | V | Q | S | N | L | K | P | . |
L | D | I | N | E | K | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |
|
|
|   |   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|
|   |   | . |
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
Template Sequence |   |
N | F | V | E | T | M | N | K | Y | . |
V | Q | Q | F | G | L | K | N | T | N | F | T | T | P | H | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | D | D | P | N | Q | Y | S | S | A | R | D | M | A | I | I | G | A | H | I | I | R | D | L | P | E | E | Y | K | I | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | . |  |  |  | T | T |
| S | S |
| B |
| S | S | S | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| T | T |
| B | B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  | G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
146 | . | . | . | 150 | . | . | . | . | |
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . |
  |
  |   |
264 | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | |
|
. | . | . | . | . | . | 340 | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
| . | . |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
L | Q | Q | G | I | Q | L | A | Q | S | R | Y | W | Q | T | G | D | M | Y | Q | G | L | G | W | E | M | L | D | W | P | V | N | P | D | S | I | I | N | G | S | D | N | K | I | A | L | A | A | R | P | V | K | A | I | T | P | P | T | P | A | V | R | A | S | W | V | H | K | T | G | . |
. |
A | T | G | G | F | G | S | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| . | . |   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|   |
|   |   |
|
|   |   |   |
|
Template Sequence |   |
S | E | K | D | F | T | F | N | K | I | K | Q | P | N | R | N | G | L | L | W | D | K | T | I | N | V | D | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | K | T | G | H | T | S | Q | A | G | Y | N | L | V |
Template Known Secondary structure |   |
G |
|
|  |  |  |  | T | T |  |  |  |  |
| S |
| G | G | G | G |
| T | T | S |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  | T | T | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
  |
  |   |
342 | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | A | F | I | P | E | K | E | L | G | I | V | M | L | A | N | K | N | Y | P | N | P | A | R | V | D | A | A | W | Q | I | L | N |
Query Conservation |   |
  |   |   |   |
|
|   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |
Template Sequence |   |
A | S | A | T | T | S | N | N | M | R | L | I | S | V | V | M | G | V | P | T | Y | K | G | R | E | V | E | S | K | K | L | L | Q |
Template Known Secondary structure |   |
 |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . |
  |