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Job DescriptionP76399
Confidence100.00%DateThu Jan 5 12:22:40 GMT 2012
Rank2Aligned Residues984
% Identity28%Templatec1oy8A_
PDB info PDB header:membrane proteinChain: A: PDB Molecule:acriflavine resistance protein b; PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
Resolution3.63 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   910.........20.........30.........40.........50.........60.........70.........80.... ...
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Query Sequence  YRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIIVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSS. SLG
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Template Sequence  DRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTG
Template Known Secondary structure 

TTS


SS


S


TT

TT



SS

TTS
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   7..10.........20.........30.........40.........50.........60.........70.........80......
 
   88.90.........100.........110.........120.........130.........140..... ....150.........160.....
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Query Sequence  STRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLT. . SDTYSQGELYDFASTQLAPT
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Template Sequence  TVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEV. QQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDA
Template Known Secondary structure 

TT

TTTGGGS
.TS





SSS


TTTTT
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   87..90.........100.........110.........120.. .......130.........140.........150.........160.....
 
   166...170.........180.........190.........200.........210.........220 .........230.........
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Query Sequence  ISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAVSNANVRKPQGAL. . . . . . EDGTHRWQIQTNDELKTAA
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Template Sequence  ISRTSGVGDVQLFGS. QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTE
Template Known Secondary structure  TTTTTSS
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TTT

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S
SS

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S
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   166...170.........180 .........190.........200.........210.........220.........230.........240....
 
   240....... ..250.........260.........270.........280.........290.........300.........310........
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Query Sequence  EYQPLIIH. YNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQ
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Template Sequence  EFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIV
Template Known Secondary structure  T
TTTS

S
TT
TT

TS

S
SSTTTSSS

SS
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   245....250.........260.........270.........280.........290.........300.........310.........320....
 
   319320.........330.........340.........350.........360.........370.........380.........390........
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Query Sequence  IAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGF
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Template Sequence  YPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGL
Template Known Secondary structure 

SBS


TTTTTTTTTTT

S
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   325....330.........340.........350.........360.........370.........380.........390.........400....
 
   399400.........410.... .....420.........430.........440.........450.........460.........470.......
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Query Sequence  VVDDAIVVLENIARHL. EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLV
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Template Sequence  LVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLV
Template Known Secondary structure  T


STTTTSTTTT


GGG
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   405....410.........420.........430.........440.........450.........460.........470.........480....
 
   478.480.........490.........500.........510.........520.........530.........540.........550.......
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Query Sequence  SLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDT
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Template Sequence  ALILTPALCATMLKF. . . . . . . . . GWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQ
Template Known Secondary structure  TTTS


.........T

SS
B
SS




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   485....490......... 500.........510.........520.........530.........540.........550.....
 
   558.560.........570.........580.........590.........600 .........610.........620... .....
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Query Sequence  GVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTG. . . . . . GSRVNSGMMFITLKPRDERSETA. . . QQIID
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Template Conservation           
 
     
      

  
                                
                  
Template Sequence  GVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITM
Template Known Secondary structure  S

TT

TS
TTT
SS


GGG

SSTTS
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   570.........580.........590.........600.........610.........620.........630.........640.........
 
   629630.........640.........650.........660.. .......670.........680.........690.........700.......
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Query Sequence  RLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQ. YTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLV
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Template Conservation                                         
     
      
   
        
              
Template Sequence  RATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPMLTSVRPNGLEDTPQFKID
Template Known Secondary structure  TTS
SS

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SS
SS

SS
SS







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   650.........660.........670.........680.........690.........700.........710.........720.........
 
   708.710.........720.........730.........740.........750.........760.........770.........780.......
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Query Sequence  YDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPA
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Template Sequence  IDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWE
Template Known Secondary structure 

T

T
TT


GGGSSSGGGGGG

TTS


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   731........740.........750.........760.........770.........780.........790.........800.........810
 
   788.790.........800.........810.........820.........830.........840.........850.........860.......
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Query Sequence  NAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVL
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Template Sequence  YGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASK. . LPTGVGYDWSGNQAPS. . . . . . . . . LYAISLIVVFLCL
Template Known Secondary structure 

STT

SSS
TT..S
TT


T.........T
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   811........820.........830.........840.........850 .........860...... ...870.........
 
   868.870.........880.........890.........900.........910.........920.........930.........940.......
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Query Sequence  GILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQAC
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Template Sequence  AALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAV
Template Known Secondary structure  TSS

SSSGGGTGGGSS

B
SSS


TTT
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   889890.........900.........910.........920.........930.........940.........950.........960........
 
   948.950.........960.........970.........980.........990.........1000.........1010....
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Query Sequence  LLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLR
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Template Sequence  RMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSR
Template Known Secondary structure  TTTSTT

SS
STSSSSSSTTT
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   969970.........980.........990.........1000.........1010.........1020.........1030.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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