Job Description P64610 Confidence 99.60% Date Thu Jan 5 12:09:54 GMT 2012 Rank 185 Aligned Residues 173 % Identity 14% Template c3k54A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases. Resolution 1.94 Å

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		3	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.			.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80
Predicted Secondary structure																							.	.
Query SS confidence																							.	.
Query Sequence		R	L	S	E	Q	S	P	L	G	T	G	R	H	R	K	C	Y	A	H	P	E	.	.	D	A	Q	R	C	I	K	I	V	Y	H	R	G	D	G	G	D	K	E	I	R	R	E	L	K	Y	Y	A	H	L	G	R	R	L	K	D	W	S	G	I	P	R	Y	H	G	T	V	E	T	D	C	G	T	G	Y	V	Y
Query Conservation																							.	.
Alig confidence																							.	.										.	.	.	.	.	.	.	.														.	.	.	.	.
Template Conservation																																		.	.	.	.	.	.	.	.														.	.	.	.	.
Template Sequence		D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	G	Q	Y	D	V	A	I	K	M	I	.	.	.	.	.	.	.	.	K	E	F	I	E	E	A	K	V	M	M	N	L	.	.	.	.	.	S	H	E	K	L	V	Q	L	Y	G	V	C	T	K	Q	R	P	I	F	I	I	T
Template Known Secondary structure		G									S	T	T	S	S								T	T	T									.	.	.	.	.	.	.	.				T	T									.	.	.	.	.			T	T	B									S	S	S	S
Template Predicted Secondary structure																																		.	.	.	.	.	.	.	.														.	.	.	.	.
Template SS confidence
		401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.									.	.	.	.	.	.	.	440	.	.	.	.	.						.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.
		81	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
Predicted Secondary structure
Query SS confidence
Query Sequence		D	V	I	A	D	F	D	G	K	P	S	I	T	L	T	E	F	A	E	Q	C	R	Y	E	E	D	I	A	Q	L	R	Q	L	L	K	Q	L	K	R	Y	L	Q	D	N	R	I	V	T	M	S	L	K	P	Q	N	I	L	C	H	R	I	S	E	S	E	V	I	P	V	V	C	D	N	I	G	E	S	T	L	I
Query Conservation
Alig confidence																	.	.	.																																													.	.	.	.							.
Template Conservation																	.	.	.																																													.	.	.	.							.
Template Sequence		E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	.	.	.	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	.	.	.	.	V	V	K	V	S	D	.	F	G	F	P	V	R	W
Template Known Secondary structure					T	T										G	.	.	.	G	G																								T	T				S			S	G	G	G					T	T		.	.	.	.							.					G	G	G
Template Predicted Secondary structure																	.	.	.																																													.	.	.	.							.
Template SS confidence
		475	.	.	.	.	480	.	.	.	.	.	.	.	.	.				490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.					.	.	.	.	.	.		540	.	.	.	.	.	.
		161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	L	A	T	W	S	K	W	C	C	L	R	K	Q	E	R	L	W	K	R	F	I	A	Q	P	A	L	A	I	A	L	Q	K	D	L	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	P	P	E	V	L	M	Y	S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E
Template Known Secondary structure																														T	T	S			T	T	T
Template Predicted Secondary structure
Template SS confidence
		564	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions