|   |
2 | . | . | . | . | . | . | |
. | 10 | . | . | . | . | . | . | . | . | . | 20 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|  |  |  |  |  |  | . |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
R | E | A | F | I | C | D | . |
G | I | R | T | P | I | G | R | Y | G | G | A | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |
|   |
|
|
| . |   |   |   |
|
|
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|   |
|
|
|   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | R | V | V | V | T | G | L | G | M | V | T | P | L | G | R | G | V | E | T | T | W | R | R | L | I | D | G | E | C | G | I | R | G | L | T | L | D | D | L | K | M | K | S | F | D | E | E | T | K | L | Y | T | F | D | Q | L | S | S | K | V | A | A | F | V | P | Y | G | S | N | P | G | E | F | D | E | A | L | W | L |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  | S |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |
|
| G | G | G | G |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  | T |
| S |
|
|  |  |  |
|
|
| B | S | S | S | T | T | S | B |
|  |  |  |  | S |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
31 | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 |
  |
  |   |
|
|
|
22 | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 60 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
| . | . | . | . | . |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
S | S | V | R | A | D | D | L | A | A | I | P | L | R | E | L | L | V | R | N | P | R | L | D | A | E | C | I | D | . |
. |
. |
. |
. |
D | V | I | L | G | C | A | N | Q | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | E | D | N | R | N | V | A |
Query Conservation |   |
. | . | . |   |   |   |
|   |   |
|
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |   |   |
|
|
| . | . | . | . | . |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|
|   | . |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
N | S | K | A | V | A | N | F | I | G | Y | A | V | C | A | A | D | E | A | L | R | . |
D | A | E | W | L | P | T | E | E | E | E | K | E | R | T | G | V | S | I | G | G | G | I | G | S | I | C | D | I | V | E | A | A | Q | L | I | C | E | K | R | L | R | R | L | S | P | F | F | I | P | K | I | L | V | N | M | A | S |
Template Known Secondary structure |   |
| S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  | T | T |
|
|
|
| S |  |  |  |  |  | T |  |  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| G | G | G |
|
| T | T |  |  |  |  |  |
| T | T |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
111 | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | |
. | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . |
  |
  |   |
69 | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | M | A | T | L | L | A | G | L | P | Q | S | V | S | G | T | T | I | N | R | L | C | G | S | G | L | D | A | L | G | F | A | A | R | A | I | K | A | G | D | G | D | L | L | I | A | G | G | V | E | S | M | S | R | A | P | F | V | M | G | K | A | A | S | A | F | S | R | Q | A | E | M | F | D | T | T | I | G | W | R |
Query Conservation |   |
  |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|   |
|
|   |   |
|   |
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |
|
|   |   |   |
|
| . | . |   |
|
|   |   |
|
|   |   |
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   | . | . | . | . | . | . |
Template Sequence |   |
G | H | V | S | M | K | Y | G | F | . |
. |
Q | G | P | N | H | A | A | V | T | A | C | A | T | G | A | H | S | I | G | D | A | T | R | M | I | Q | F | G | D | A | D | V | M | V | A | G | G | T | E | S | S | I | D | A | L | S | V | A | G | F | S | R | S | R | A | L | S | T | K | F | N | S | S | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T |
| . | . |
| S |
|  |  |
|
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| S |  |  |  |  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  | T | T |
| B |
|
| T | T | T | T |
| . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
190 | . | . | . | . | . | . | . | . | |
|
. | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
|
|
|
|
  |
  |   |
149 | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | V | N | P | L | M | A | Q | Q | F | G | T | D | S | M | P | E | T | A | E | N | V | A | E | L | L | K | I | S | R | E | D | Q | D | S | F | A | L | R | S | Q | Q | R | T | A | K | A | Q | S | S | G | I | L | A | E | E | I | V | P | V | V | L | K | N | K | K | G | V | V | T | E | I | Q | H | D | E | H | L | R | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | T | T | L | E | Q | L | R | G | L | K | A | P | F | R | A | N | G | V | I | T | A | G | N | A | S | G | V | N | D | G | A | A | A | L | I | I | A | S | E | Q | M | A | A | A | Q | G | L | T | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|   |
|
|   |
|   |
|   |
|   |   |
|
|   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|
|
|   |   |   |   |
|   |
|   |
|
|
|
|   |   |
|
|
|
|   |   |   |   |
|   |   |
|
|
|   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | Q | E | A | S | R | P | F | D | C | D | R | D | G | F | V | I | G | E | G | S | G | V | I | V | L | E | E | Y | E | H | A | K | R | R | G | A | K | I |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | G | G | G | S |
|
| T | T |
| T | T |
|
| S | B |
|
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
  |