|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | A | L | S | K | L | K | A | E | E | G | I | W | M | T | D | V | P | V | P | E | L | G | H | N | D | L | L | I | K | I | R | K | T | A | I | C | G | T | D | V | H | I | Y | N | W | D | E | W | S | Q | K | T | I | P | V | P | M | V | V | G | H | E | Y | V | G | E | V | V | G | I | G | Q | E | V | K | G | F | K |
Query Conservation |   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|   |
|
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   | . | . | . |   |
|   |
|   |
|   |
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |
Template Sequence |   |
T | T | G | W | A | A | R | D | P | S | G | I | L | S | P | Y | T | Y | T | L | R | E | T | G | P | E | D | V | N | I | R | I | I | C | C | G | I | C | H | T | D | L | H | Q | T | K | N | D | L | G | M | S | N | . |
. |
. |
Y | P | M | V | P | G | H | E | V | V | G | E | V | V | E | V | G | S | D | V | S | K | F | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| S | T | T |
|
|  |  |  |  |  |  |  |
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  | T |
| T | T | T |
|
|
| . | . | . | S | S | B |
|
|
|
|  |  |  |  |  |  |  |  |  |
| S | S |
|
| S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
|
|
. | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | |
. | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | G | D | R | V | S | G | E | G | H | I | T | . |
C | G | H | C | R | N | C | R | G | G | R | T | H | L | C | R | . |
. |
. |
. |
. |
. |
. |
N | T | I | G | V | G | V | N | R | P | G | C | F | A | E | Y | L | V | I | P | A | F | N | A | F | K | I | P | D | N | I | S | D | D | L | A | A | I | F | D | P | F | G | N |
Query Conservation |   |
|
|
|
|
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | G | D | I | V | G | V | G | C | L | V | G | C | C | G | G | C | S | P | C | E | R | D | L | E | Q | Y | C | P | K | K | I | W | S | Y | N | D | V | Y | I | N | G | Q | P | T | Q | G | G | F | A | K | A | T | V | V | H | Q | K | F | V | V | K | I | P | E | G | M | A | V | E | Q | A | A | P | L | L | C | A | G | V |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |
| S |  |  |  |
|
| S | S | S |  |  |  |  | T | T |
| G | G | G |
| T | T |
|  |  | T | T | T | S | B |
| T | T | S |
| B |
|
|
| S | S | B | S |
|  |  |  |  | G | G | G |  |  |  |
|
| S | S |
|
|  |  |  |  | T | G | G | G | T |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
87 | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . |
  |
  |   |
153 | . | . | . | . | |
|
|
. | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  | . | . | . |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | V | H | T | A | . |
. |
. |
L | S | F | D | L | V | G | E | D | V | L | V | S | G | A | G | P | I | G | I | M | A | A | A | V | A | K | H | V | G | A | R | N | V | V | I | T | D | V | N | E | Y | R | L | E | L | A | R | K | M | G | I | T | R | A | V | N | V | A | K | E | N | L | N | D | V | M | A | E | L | G | M |
Query Conservation |   |
  |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
Template Sequence |   |
T | V | Y | S | P | L | S | H | F | G | L | K | Q | P | G | L | R | G | G | I | L | G | L | G | G | V | G | H | M | G | V | K | I | A | K | A | M | G | H | H | V | T | V | I | S | S | S | N | K | K | R | E | E | A | L | Q | D | L | G | A | D | D | Y | V | I | G | S | D | Q | A | K | M | S | E | L | A | D | . |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | S | T | T | S | T | T |
|  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  | S | S | T | T |  |  |  |  |  |  | T | T | S |
|
| S |
|  |  |  | T | T |
|  |  |  |  |  |  | S | T | T | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
167 | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
|
  |
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | E | G | F | D | V | G | L | E | M | S | G | A | P | P | A | F | R | T | M | L | D | T | M | N | H | G | G | R | I | A | M | L | G | I | P | P | S | D | M | S | I | D | W | T | K | V | I | F | K | G | L | F | I | K | G | I | Y | G | R | E | M | F | E | T | W | Y | K | M | A | A | L | I | Q | S | G | L | D | L | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Template Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |
|
|   |   |
| . |   |
|   |
Template Sequence |   |
. |
. |
S | L | D | Y | V | I | D | T | V | P | V | H | H | A | L | E | P | Y | L | S | L | L | K | L | D | G | K | L | I | L | M | G | V | I | N | N | P | L | Q | F | L | T | P | L | L | M | L | G | R | K | V | I | T | G | S | F | I | G | S | M | K | E | T | . |
E | E | M | L | E | F | C | K | E | K | . |
G | L | S |
Template Known Secondary structure |   |
. | . | T |  |  |  |  |  |  |
|
|
| S |
|
|
| S |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
| S |
|
| S | S |
|
|
|
|
|  |  |  |  |  |  |  | T |
|  |  |  |  |
|
| S |
|
|  |  |  |  | . |  |  |  |  |  |  |  |  |  | T | . | T |
|
|
Template Predicted Secondary structure |   |
. | . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  | . |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
. | . | . | 310 | . | . | . | . | . | . | |
. | . | . |
  |
  |   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | |
. | . | . | . | . | . | 340 | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Query Sequence |   |
P | I | I | T | H | R | F | S | I | D | D | F | Q | K | G | F | D | A | M | R | S | G | Q | S | . |
G | K | V | I | L | S | W | D |
Query Conservation |   |
  |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |
|   |   |
|   |   | . |
|
|
|
|
|   |   |
|
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   | . |   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|   |
|   |
Template Sequence |   |
S | I | I | E | . |
V | V | K | M | D | Y | V | N | T | A | F | E | R | L | E | K | N | D | V | R | Y | R | F | V | V | D | V | E |
Template Known Secondary structure |   |
|
|  |  | . |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  | T | T |
| S | S | S |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
320 | . | . | . | |
. | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . |
  |