|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | |
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | A | L | S | K | L | K | A | E | E | G | I | W | M | T | D | V | P | V | P | E | . |
L | G | H | N | D | L | L | I | K | I | R | K | T | A | I | C | G | T | D | V | H | I | Y | N | W | D | E | W | S | Q | K | T | I | P | V | P | M | V | V | G | H | E | Y | V | G | E | V | V | G | I | G | Q | E | V | K | G | F |
Query Conservation |   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   | . |   |   |   |   |
|
|
|
|
|
|   |
|   |
|
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   | . | . | . | . |   |   |
|   |
|   |
|   |
|   |   |
|   |
|   |   |
|
|   |   | . | . | . |   |
Template Sequence |   |
M | K | A | I | I | V | K | P | P | N | A | G | V | Q | V | K | D | V | D | E | K | K | L | D | S | Y | G | K | I | K | I | R | T | I | Y | N | G | I | C | G | T | D | R | E | I | V | N | G | K | L | K | G | . |
. |
. |
. |
K | D | F | L | V | L | G | H | E | A | I | G | V | V | E | E | S | Y | H | G | . |
. |
. |
F |
Template Known Secondary structure |   |
|  |  |  |  |  |
| T | T | S |
|
|
|  |  |  |  |
|
| G | G | G | S |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  | T | T |
|
|
|
| . | . | . | . |
| S |
|  |  |
|
| S |  |  |  |  |  |  | S | S |
|
| S | S | . | . | . |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
|
|
|
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
|
. |
  |
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | |
|
|
. | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | I | G | D | R | V | S | G | E | G | H | I | T | C | G | H | C | R | N | C | R | G | G | R | T | H | L | C | R | N | T | I | G | V | . |
. |
. |
G | V | N | R | P | G | C | F | A | E | Y | L | V | I | P | A | F | N | A | F | K | I | P | D | N | I | S | D | D | L | A | A | I | F | D | P | F | G | N | A | V | H | T |
Query Conservation |   |
  |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
S | Q | G | D | L | V | M | P | V | N | R | R | G | C | G | I | C | R | N | C | L | V | G | R | P | D | F | C | E | T | G | E | F | G | E | A | G | I | H | K | M | D | G | F | M | R | E | W | W | Y | D | D | P | K | Y | L | V | K | I | P | K | S | I | E | D | I | G | I | L | A | Q | P | L | A | D | I | E | K | S | I |
Template Known Secondary structure |   |
| T | T |
|  |  |  |  |
| S |  |  |
|
| S | S | S |  |  |  |  | T | T |
| G | G | G |
| S | S | S |
|
|  |  |  | T | T | B |  |  |
|
| S |
| B | S |  |  |  |  |
| G | G | G |  |  |  |  |
| G | G | G | T | T | T | G | G | G |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
157 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . |
Predicted Secondary structure |   |
 |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | F | D | L | V | G | E | D | V | L | V | S | G | A | G | P | I | G | I | M | A | A | A | V | A | K | H | V | G | A | R | N | V | V | I | T | D | V | N | E | Y | R | L | E | L | A | R | K | M | G | I | T | R | A | V | N | V | A | K | E | N | L | N | D |
Query Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|
| . |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | E | I | L | E | V | Q | K | R | V | P | V | W | T | C | D | D | G | T | L | N | C | R | K | V | L | V | V | G | T | G | P | I | G | V | L | F | T | L | L | F | R | T | Y | G | L | . |
E | V | W | M | A | N | R | R | E | P | T | E | V | E | Q | T | V | I | E | E | T | K | T | N | Y | Y | N | S | S | N | G | Y | D |
Template Known Secondary structure |   |
 |  |  |  |  |  | G | G | G | S | S |
|
| S |
| T | T | S | S | S | T | T |
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . |  |  |  |  |  |  | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |
| T | T |
| S |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
. | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
  |
  |   |
223 | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
|
|
|
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | M | A | E | L | G | M | T | E | G | F | D | V | G | L | E | M | S | G | A | P | P | A | F | R | T | M | L | D | T | M | N | H | G | G | R | I | A | M | L | G | I | P | P | S | D | . |
. |
. |
. |
M | S | I | D | W | T | K | V | I | F | K | G | L | F | I | K | G | I | Y | G | R | E | M | F | E | T | W | Y | K | M |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
K | L | K | D | S | V | G | . |
K | F | D | V | I | I | D | A | T | G | A | D | V | N | I | L | G | N | V | I | P | L | L | G | R | N | G | V | L | G | L | F | G | F | S | T | S | G | S | V | P | L | D | Y | K | T | L | Q | E | I | V | H | T | N | K | T | I | I | G | L | V | N | G | Q | K | P | H | F | Q | Q | A | V |
Template Known Secondary structure |   |
 |  |  |  |  | T |
| . |
|  |  |  |  |  |  |
|
|
|
| B | T |  |  |  |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  |
| S |
|
|
| B |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | . | . | . | . | |
. | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
  |
  |   |
299 | 300 | . | . | . | . | . | . | |
|
|
|
. | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | L | I | Q | S | G | L | . |
. |
. |
. |
D | L | S | P | I | I | T | H | R | F | S | I | D | D | F | Q | K | G | F | D | A | M | R | S | G | Q | S | G | K | V | I | L | S | W | D |
Query Conservation |   |
  |   |
|   |   |   |
|   | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |
|
|
|
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |
Template Sequence |   |
V | H | L | A | S | W | K | T | L | Y | P | K | A | A | K | M | L | I | T | K | T | V | S | I | N | D | E | K | E | L | L | K | V | L | R | E | K | E | H | G | E | I | K | I | R | I | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | S |  |  |  |  | T | T | S |
|
|  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |
|
|
| T | T |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
  |