Job Description P0AG93 Confidence 5.97% Date Thu Jan 5 11:28:29 GMT 2012 Rank 46 Aligned Residues 176 % Identity 13% Template c3g5uB_ PDB info PDB header:membrane protein Chain: B: PDB Molecule:multidrug resistance protein 1a; PDBTitle: structure of p-glycoprotein reveals a molecular basis for2 poly-specific drug binding Resolution 3.80 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		146	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.														.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.
Predicted Secondary structure																																																		.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																		.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		G	A	M	A	L	M	A	A	L	L	S	I	L	V	Y	V	G	F	R	F	E	W	R	L	A	A	G	V	V	I	A	L	A	H	D	V	I	I	T	L	G	I	L	S	L	F	H	I	.	.	.	.	.	.	.	.	.	.	.	.	.	E	I	D	L	T	I	V	A	S	L	M	S	V	I	G	Y	S	L	N
Query Conservation																																																		.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																																		.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	M	F	F	Q	A	M	A	T	F	F	G	G	F	I	I	G	F	T	R	G	W	K	L	T	L	V	I	L	A	I	S	P	V	L	G	L	S	A	G	I	W	A	K	I	L	S	S	F	T	D	K	E	L	H	A	Y	A	K	A	G	A	V	A	E	E	V	L	A	A	I	R	T	V	I	A	F	G	G	Q
Template Known Secondary structure																					T	T	T	T	S																																							T	T	T											T	T
Template Predicted Secondary structure
Template SS confidence
		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
		213	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	S	I	V	V	S	D	R	I	R	E	N	F	R	K	I	R	R	G	T	P	Y	E	I	F	N	V	S	L	T	Q	T	L	H	R	T	L	I	T	S	G	T	T	L	M	V	I	L	M	L	Y	L	F	G	G	P	V	L	E	G	F	S	L	T	M	L	I	G	V	S	I	G	T	A	S	S	I	Y	V	A
Query Conservation
Alig confidence			.	.
Template Conservation			.	.
Template Sequence		K	.	.	K	E	L	E	R	Y	N	N	N	L	E	E	A	K	R	L	G	I	K	K	A	I	T	A	N	I	S	M	G	A	A	F	L	L	I	Y	A	S	Y	A	L	A	F	W	Y	G	T	S	L	V	I	S	K	E	Y	S	I	G	Q	V	L	T	V	F	F	S	V	L	I	G	A	F	S	V	G	Q	A
Template Known Secondary structure			.	.	S																		T	T	T																																S	S	S		S	S
Template Predicted Secondary structure			.	.
Template SS confidence
		267			.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.
		293	.	.	.	.	.	.	300	.							.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.
Predicted Secondary structure											.	.	.	.	.	.
Query SS confidence											.	.	.	.	.	.
Query Sequence		S	A	L	A	L	K	L	G	M	.	.	.	.	.	.	K	R	E	H	M	L	Q	Q	K	V	E	K	E	G	A	D	Q	P	S	I	L	P
Query Conservation											.	.	.	.	.	.
Alig confidence											.	.	.	.	.	.
Template Conservation
Template Sequence		S	P	N	I	E	A	F	A	N	A	R	G	A	A	Y	E	V	F	K	I	I	D	N	K	P	S	I	D	S	F	S	K	S	G	H	K	P
Template Known Secondary structure																					T	T	S						S	S			S
Template Predicted Secondary structure
Template SS confidence
		345	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions