Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP36655
DateThu Jan 5 11:53:30 GMT 2012
Unique Job IDf02c58eb44ccad7b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1l6pa_
Top template information
Fold:Immunoglobulin-like beta-sandwich
Superfamily:Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)
Family:Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)
Confidence and coverage
Confidence:100.0% Coverage: 21%
121 residues ( 21% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
350 residues ( 62%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFAFDFQQNQHDLNLTWQIKDGYYL
Secondary structure 
SS confidence 
Disorder  ???
?????
???
???
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  YRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTLPVTINQASAGATLTVTYQ
Secondary structure 
SS confidence 
Disorder 
?????????
?
??
?
??????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  GCADAGFCYPPETKTVPLSEVVANNAAPQPVSVPQQEQPTAQLPFSALWALLIGIGIAFT
Secondary structure 
SS confidence 
Disorder 
????????????????????????????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  PCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMALTYTALGLVVAAAGLQFQAALQ
Secondary structure 
SS confidence 
Disorder 
?????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  HPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLI
Secondary structure 
SS confidence 
Disorder 
??
??
?????????????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  CSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLITVFGNRLLPKSGPWMEQ
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  VKTAFGFVILALPVFLLERVIGDVWGLRLWSALGVAFFGWAFITSLQAKRGWMRIVQIIL
Secondary structure 
SS confidence 
Disorder 
??????????
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  LAAALVSVRPLQDWAFGATHTAQTQTHLNFTQIKTVDELNQALVEAKGKPVMLDLYADWC
Secondary structure 
SS confidence 
Disorder 
??????????????????
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  VACKEFEKYTFSDPQVQKALADTVLLQANVTANDAQDVALLKHLNVLGLPTILFFDGQGQ
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........550.........560.....
Sequence  EHPQARVTGFMDAETFSAHLRDRQP
Secondary structure 
SS confidence 
Disorder 
????????
????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1l6p chain A

3D model

Region: 23 - 143
Aligned: 121
Modelled: 121
Confidence: 100.0%
Identity: 100%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)
Family: Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)

Phyre2

PDB 1jpe chain A

3D model

Region: 29 - 144
Aligned: 116
Modelled: 116
Confidence: 100.0%
Identity: 100%
PDB header:electron transport
Chain: A: PDB Molecule:dsbd-alpha;
PDBTitle: crystal structure of dsbd-alpha; the n-terminal domain of2 dsbd

Phyre2

PDB 2k0r chain A

3D model

Region: 24 - 148
Aligned: 125
Modelled: 125
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbd;
PDBTitle: solution structure of the c103s mutant of the n-terminal2 domain of dsbd from neisseria meningitidis

Phyre2

PDB 2fwh chain A domain 1

3D model

Region: 447 - 562
Aligned: 116
Modelled: 116
Confidence: 99.9%
Identity: 100%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Thioltransferase

Phyre2

PDB 3f9u chain A

3D model

Region: 458 - 563
Aligned: 104
Modelled: 104
Confidence: 99.8%
Identity: 21%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative exported cytochrome c biogenesis-related protein;
PDBTitle: crystal structure of c-terminal domain of putative exported cytochrome2 c biogenesis-related protein from bacteroides fragilis

Phyre2

PDB 2ju5 chain A

3D model

Region: 435 - 563
Aligned: 125
Modelled: 129
Confidence: 99.8%
Identity: 17%
PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin disulfide isomerase;
PDBTitle: dsbh oxidoreductase

Phyre2

PDB 2dlx chain A domain 1

3D model

Region: 458 - 563
Aligned: 102
Modelled: 106
Confidence: 99.8%
Identity: 12%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: UAS domain

Phyre2

PDB 2kuc chain A

3D model

Region: 443 - 563
Aligned: 115
Modelled: 121
Confidence: 99.8%
Identity: 25%
PDB header:isomerase
Chain: A: PDB Molecule:putative disulphide-isomerase;
PDBTitle: solution structure of a putative disulphide-isomerase from bacteroides2 thetaiotaomicron

Phyre2

PDB 3ira chain A

3D model

Region: 435 - 563
Aligned: 126
Modelled: 129
Confidence: 99.8%
Identity: 14%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved protein;
PDBTitle: the crystal structure of one domain of the conserved protein from2 methanosarcina mazei go1

Phyre2

PDB 3fk8 chain A

3D model

Region: 442 - 563
Aligned: 119
Modelled: 122
Confidence: 99.7%
Identity: 15%
PDB header:isomerase
Chain: A: PDB Molecule:disulphide isomerase;
PDBTitle: the crystal structure of disulphide isomerase from xylella fastidiosa2 temecula1

Phyre2

PDB 2l57 chain A

3D model

Region: 444 - 565
Aligned: 116
Modelled: 122
Confidence: 99.7%
Identity: 14%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of an uncharacterized thioredoin-like protein from2 clostridium perfringens

Phyre2

PDB 1sen chain A

3D model

Region: 448 - 562
Aligned: 109
Modelled: 115
Confidence: 99.7%
Identity: 20%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Thioltransferase

Phyre2

PDB 1sen chain A

3D model

Region: 448 - 562
Aligned: 109
Modelled: 115
Confidence: 99.7%
Identity: 20%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:thioredoxin-like protein p19;
PDBTitle: endoplasmic reticulum protein rp19 o95881

Phyre2

PDB 2hyx chain A

3D model

Region: 431 - 563
Aligned: 130
Modelled: 133
Confidence: 99.7%
Identity: 15%
PDB header:unknown function
Chain: A: PDB Molecule:protein dipz;
PDBTitle: structure of the c-terminal domain of dipz from mycobacterium2 tuberculosis

Phyre2

PDB 2ppt chain A

3D model

Region: 445 - 563
Aligned: 109
Modelled: 119
Confidence: 99.7%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin-2;
PDBTitle: crystal structure of thioredoxin-2

Phyre2

PDB 3p2a chain B

3D model

Region: 435 - 562
Aligned: 118
Modelled: 125
Confidence: 99.6%
Identity: 18%
PDB header:oxidoreductase
Chain: B: PDB Molecule:putative thioredoxin-like protein;
PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis

Phyre2

PDB 2diy chain A

3D model

Region: 435 - 565
Aligned: 120
Modelled: 128
Confidence: 99.6%
Identity: 14%
PDB header:protein binding
Chain: A: PDB Molecule:thioredoxin-like protein 2;
PDBTitle: the solution structure of the thioredoxin domain of human2 thioredoxin-like protein 2

Phyre2

PDB 3p2a chain A

3D model

Region: 435 - 562
Aligned: 118
Modelled: 125
Confidence: 99.6%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin-like protein;
PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis

Phyre2

PDB 1z5y chain E domain 1

3D model

Region: 466 - 563
Aligned: 90
Modelled: 98
Confidence: 99.6%
Identity: 23%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Glutathione peroxidase-like

Phyre2

PDB 3ul3 chain A

3D model

Region: 465 - 562
Aligned: 89
Modelled: 98
Confidence: 99.6%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: structural insights into thioredoxin-2: a component of malaria2 parasite protein secretion machinery

Phyre2

PDB 1jfu chain A

3D model

Region: 423 - 561
Aligned: 136
Modelled: 136
Confidence: 99.3%
Identity: 25%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Glutathione peroxidase-like

Phyre2

PDB 3kp9 chain A

3D model

Region: 334 - 559
Aligned: 196
Modelled: 196
Confidence: 99.1%
Identity: 13%
PDB header:blood coagulation,oxidoreductase
Chain: A: PDB Molecule:vkorc1/thioredoxin domain protein;
PDBTitle: structure of a bacterial homolog of vitamin k epoxide reductase

Phyre2
1
d1l6pa_
2
c1jpeA_
3
c2k0rA_
4
d2fwha1
5
c3f9uA_
6
c2ju5A_
7
d2dlxa1
8
c2kucA_
9
c3iraA_
10
c3fk8A_
11
c2l57A_
12
d1sena_
13
c1senA_
14
c2hyxA_
15
c2pptA_
16
c3p2aB_
17
c2diyA_
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c3p2aA_
19
d1z5ye1
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c3ul3A_
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c3kp9A_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1l6pa_
100.0 100 Fold:Immunoglobulin-like beta-sandwich
Superfamily:Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)
Family:Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)
2c1jpeA_
100.0 100 PDB header:electron transport
Chain: A: PDB Molecule:dsbd-alpha;
PDBTitle: crystal structure of dsbd-alpha; the n-terminal domain of2 dsbd
3c2k0rA_
100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbd;
PDBTitle: solution structure of the c103s mutant of the n-terminal2 domain of dsbd from neisseria meningitidis
4d2fwha1
99.9 100 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
5c3f9uA_
99.8 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative exported cytochrome c biogenesis-related protein;
PDBTitle: crystal structure of c-terminal domain of putative exported cytochrome2 c biogenesis-related protein from bacteroides fragilis
6c2ju5A_
99.8 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin disulfide isomerase;
PDBTitle: dsbh oxidoreductase
7d2dlxa1
99.8 12 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:UAS domain
8c2kucA_
99.8 25 PDB header:isomerase
Chain: A: PDB Molecule:putative disulphide-isomerase;
PDBTitle: solution structure of a putative disulphide-isomerase from bacteroides2 thetaiotaomicron
9c3iraA_
99.8 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved protein;
PDBTitle: the crystal structure of one domain of the conserved protein from2 methanosarcina mazei go1
10c3fk8A_
99.7 15 PDB header:isomerase
Chain: A: PDB Molecule:disulphide isomerase;
PDBTitle: the crystal structure of disulphide isomerase from xylella fastidiosa2 temecula1
11c2l57A_
99.7 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of an uncharacterized thioredoin-like protein from2 clostridium perfringens
12d1sena_
99.7 20 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
13c1senA_
99.7 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:thioredoxin-like protein p19;
PDBTitle: endoplasmic reticulum protein rp19 o95881
14c2hyxA_
99.7 15 PDB header:unknown function
Chain: A: PDB Molecule:protein dipz;
PDBTitle: structure of the c-terminal domain of dipz from mycobacterium2 tuberculosis
15c2pptA_
99.7 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin-2;
PDBTitle: crystal structure of thioredoxin-2
16c3p2aB_
99.6 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative thioredoxin-like protein;
PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis
17c2diyA_
99.6 14 PDB header:protein binding
Chain: A: PDB Molecule:thioredoxin-like protein 2;
PDBTitle: the solution structure of the thioredoxin domain of human2 thioredoxin-like protein 2
18c3p2aA_
99.6 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin-like protein;
PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis
19d1z5ye1
99.6 23 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
20c3ul3A_
99.6 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: structural insights into thioredoxin-2: a component of malaria2 parasite protein secretion machinery
21c2vlvA_
not modelled 99.6 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin h isoform 2.;
PDBTitle: crystal structure of barley thioredoxin h isoform 2 in2 partially radiation-reduced state
22d1knga_
not modelled 99.6 18 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
23d1qgva_
not modelled 99.6 14 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:spliceosomal protein U5-15Kd
24c2f51B_
not modelled 99.5 18 PDB header:electron transport
Chain: B: PDB Molecule:thioredoxin;
PDBTitle: structure of trichomonas vaginalis thioredoxin
25d1gh2a_
not modelled 99.5 16 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
26d1xwaa_
not modelled 99.5 25 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
27d1m7ta_
not modelled 99.5 25 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
28c2l6dA_
not modelled 99.5 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: solution structure of desulfothioredoxin from desulfovibrio vulgaris2 hildenborough in its reduced form
29d2ifqa1
not modelled 99.5 27 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
30c3hypB_
not modelled 99.5 22 PDB header:electron transport
Chain: B: PDB Molecule:thioredoxin;
PDBTitle: crystal structure of bacteroides fragilis trxp_s105g mutant
31c2vimA_
not modelled 99.5 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: x-ray structure of fasciola hepatica thioredoxin
32d1ti3a_
not modelled 99.5 21 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
33d1xfla_
not modelled 99.5 19 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
34c2l5lA_
not modelled 99.5 24 PDB header:transport protein
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: solution structure of thioredoxin from bacteroides vulgatus
35c3d22A_
not modelled 99.5 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin h-type;
PDBTitle: crystal structure of a poplar thioredoxin h mutant,2 pttrxh4c61s
36c3dmlA_
not modelled 99.5 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of the periplasmic thioredoxin soxs from2 paracoccus pantotrophus (reduced form)
37c2vm2C_
not modelled 99.5 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:thioredoxin h isoform 1.;
PDBTitle: crystal structure of barley thioredoxin h isoform 12 crystallized using peg as precipitant
38c2xbqB_
not modelled 99.5 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:thioredoxin;
PDBTitle: crystal structure of reduced schistosoma mansoni2 thioredoxin pre-protein at 1.7 angstrom
39c3qdnA_
not modelled 99.5 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin protein;
PDBTitle: putative thioredoxin protein from salmonella typhimurium
40c2e0qA_
not modelled 99.5 19 PDB header:electron transport
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: crystal structure of k53e thioredoxin from sulfolobus2 tokodaii strain7
41c3razA_
not modelled 99.5 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin-related protein;
PDBTitle: the crystal structure of thioredoxin-related protein from neisseria2 meningitidis serogroup b
42c2wz9A_
not modelled 99.5 14 PDB header:protein binding
Chain: A: PDB Molecule:glutaredoxin-3;
PDBTitle: crystal structure of the thioredoxin domain of human txnl2
43d2fy6a1
not modelled 99.5 22 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
44d1ep7a_
not modelled 99.5 21 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
45c3gnjD_
not modelled 99.5 15 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:thioredoxin domain protein;
PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb
46c1xbsA_
not modelled 99.5 19 PDB header:transcription, cell cycle
Chain: A: PDB Molecule:dim1-like protein;
PDBTitle: crystal structure of human dim2: a dim1-like protein
47d1nw2a_
not modelled 99.5 22 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
48d1lu4a_
not modelled 99.5 18 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
49c2oe0B_
not modelled 99.5 19 PDB header:electron transport
Chain: B: PDB Molecule:thioredoxin-3;
PDBTitle: crystal structure of mitochondrial thioredoxin 3 from2 saccharomyces cerevisiae
50c3lwaA_
not modelled 99.5 15 PDB header:isomerase
Chain: A: PDB Molecule:secreted thiol-disulfide isomerase;
PDBTitle: the crystal structure of a secreted thiol-disulfide2 isomerase from corynebacterium glutamicum to 1.75a
51d1a8la2
not modelled 99.4 14 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:PDI-like
52c3hz4A_
not modelled 99.4 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: crystal structure of thioredoxin from methanosarcina mazei
53d1f9ma_
not modelled 99.4 21 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
54c2b1kA_
not modelled 99.4 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbe;
PDBTitle: crystal structure of e. coli ccmg protein
55d1r26a_
not modelled 99.4 18 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
56c2i1uA_
not modelled 99.4 25 PDB header:electron transport
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: mycobacterium tuberculosis thioredoxin c
57d1dbya_
not modelled 99.4 18 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
58d1st9a_
not modelled 99.4 20 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
59c1v98A_
not modelled 99.4 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: crystal structure analysis of thioredoxin from thermus thermophilus
60d1zzoa1
not modelled 99.4 19 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
61d1j08a2
not modelled 99.4 11 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:PDI-like
62c3or5A_
not modelled 99.4 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:thiol:disulfide interchange protein, thioredoxin family
PDBTitle: crystal structure of thiol:disulfide interchange protein, thioredoxin2 family protein from chlorobium tepidum tls
63d1syra_
not modelled 99.4 16 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
64c1w89E_
not modelled 99.4 23 PDB header:electron transport
Chain: E: PDB Molecule:thioredoxin;
PDBTitle: structure of the reduced form of human thioredoxin 2
65c2vocA_
not modelled 99.4 18 PDB header:electron transport
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: thioredoxin a active site mutants form mixed disulfide2 dimers that resemble enzyme-substrate reaction3 intermediate
66d1thxa_
not modelled 99.4 17 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
67c2i4aA_
not modelled 99.4 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: crystal structure of thioredoxin from the acidophile2 acetobacter aceti
68c3erwG_
not modelled 99.4 21 PDB header:oxidoreductase
Chain: G: PDB Molecule:sporulation thiol-disulfide oxidoreductase a;
PDBTitle: crystal structure of stoa from bacillus subtilis
69d2b5xa1
not modelled 99.4 14 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
70c2yzuA_
not modelled 99.4 18 PDB header:electron transport
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: crystal structure of oxidized thioredoxin from thermus thermophilus2 hb8
71c3tcoA_
not modelled 99.4 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin (trxa-1);
PDBTitle: crystallographic and spectroscopic characterization of sulfolobus2 solfataricus trxa1 provide insights into the determinants of3 thioredoxin fold stability
72c1t00A_
not modelled 99.4 20 PDB header:electron transport
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: the structure of thioredoxin from s. coelicolor
73c3emxB_
not modelled 99.4 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:thioredoxin;
PDBTitle: crystal structure of thioredoxin from aeropyrum pernix
74c3kh7A_
not modelled 99.4 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbe;
PDBTitle: crystal structure of the periplasmic soluble domain of reduced ccmg2 from pseudomonas aeruginosa
75d1fb6a_
not modelled 99.4 23 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
76d2trxa_
not modelled 99.4 20 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
77c3cmiA_
not modelled 99.4 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:peroxiredoxin hyr1;
PDBTitle: crystal structure of glutathione-dependent phospholipid peroxidase2 hyr1 from the yeast saccharomyces cerevisiae
78d1zmaa1
not modelled 99.4 12 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
79c3hczA_
not modelled 99.4 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:possible thiol-disulfide isomerase;
PDBTitle: the crystal structure of a domain of possible thiol-disulfide2 isomerase from cytophaga hutchinsonii atcc 33406.
80c3cxgA_
not modelled 99.3 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin;
PDBTitle: crystal structure of plasmodium falciparum thioredoxin, pfi0790w
81c3hdcA_
not modelled 99.3 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin family protein;
PDBTitle: the crystal structure of thioredoxin protein from geobacter2 metallireducens
82c2o7kA_
not modelled 99.3 20 PDB header:electron transport
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: s. aureus thioredoxin
83c2albA_
not modelled 99.3 23 PDB header:isomerase
Chain: A: PDB Molecule:protein disulfide-isomerase a3;
PDBTitle: nmr structure of the n-terminal domain a of the2 glycoprotein chaperone erp57
84c3lorB_
not modelled 99.3 17 PDB header:isomerase
Chain: B: PDB Molecule:thiol-disulfide isomerase and thioredoxins;
PDBTitle: the crystal structure of a thiol-disulfide isomerase from2 corynebacterium glutamicum to 2.2a
85d1v9wa_
not modelled 99.3 16 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Txnl5-like
86c3gl3D_
not modelled 99.3 20 PDB header:oxidoreductase
Chain: D: PDB Molecule:putative thiol:disulfide interchange protein
PDBTitle: crystal structure of a putative thiol:disulfide interchange2 protein dsbe from chlorobium tepidum
87d1o8xa_
not modelled 99.3 16 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
88c3dxbE_
not modelled 99.3 20 PDB header:splicing, transcription
Chain: E: PDB Molecule:thioredoxin n-terminally fused to puf60(uhm);
PDBTitle: structure of the uhm domain of puf60 fused to thioredoxin
89c2j23A_
not modelled 99.3 25 PDB header:immune protein
Chain: A: PDB Molecule:thioredoxin;
PDBTitle: cross-reactivity and crystal structure of malassezia2 sympodialis thioredoxin (mala s 13), a member of a new pan-3 allergen family
90d1o73a_
not modelled 99.3 18 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
91c2l5oA_
not modelled 99.3 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin;
PDBTitle: solution structure of a putative thioredoxin from neisseria2 meningitidis
92d1i5ga_
not modelled 99.3 16 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
93c1x5dA_
not modelled 99.3 20 PDB header:isomerase
Chain: A: PDB Molecule:protein disulfide-isomerase a6;
PDBTitle: the solution structure of the second thioredoxin-like2 domain of human protein disulfide-isomerase a6
94c3ewlA_
not modelled 99.3 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized conserved protein bf1870;
PDBTitle: crystal structure of conserved protein bf1870 of unknown function from2 bacteroides fragilis
95d1woua_
not modelled 99.3 20 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Txnl5-like
96d1jfua_
99.3 25 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
97c3d6iB_
not modelled 99.3 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:monothiol glutaredoxin-3;
PDBTitle: structure of the thioredoxin-like domain of yeast2 glutaredoxin 3
98c2dbcA_
not modelled 99.3 18 PDB header:signaling protein
Chain: A: PDB Molecule:unnamed protein product;
PDBTitle: solution structure of the thioredoxin-like domain of2 phosducin-like protein 2(pdcl2)
99c3eytA_
not modelled 99.3 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein spoa0173;
PDBTitle: crystal structure of thioredoxin-like superfamily protein spoa0173
100c2dmlA_
not modelled 99.3 18 PDB header:isomerase
Chain: A: PDB Molecule:protein disulfide-isomerase a6;
PDBTitle: the solution structure of the first thioredoxin domain of2 mouse protein disulfide-isomerase a6
101c2qsiB_
not modelled 99.2 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative hydrogenase expression/formation protein hupg;
PDBTitle: crystal structure of putative hydrogenase expression/formation protein2 hupg from rhodopseudomonas palustris cga009
102c3eurA_
not modelled 99.2 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the c-terminal domain of uncharacterized protein2 from bacteroides fragilis nctc 9343
103c2i9hA_
not modelled 99.2 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin i;
PDBTitle: nmr solution structure of the reduced form of thioredoxin 12 from yeast (trx1)
104c3ia1A_
not modelled 99.2 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:thio-disulfide isomerase/thioredoxin;
PDBTitle: crystal structure of thio-disulfide isomerase from thermus2 thermophilus
105d1oaza_
not modelled 99.2 18 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Thioltransferase
106c2dizA_
not modelled 99.2 18 PDB header:electron transport
Chain: A: PDB Molecule:thioredoxin domain-containing protein 5;
PDBTitle: the solution structure of the third thioredoxin domain of2 human thioredoxin domain-containing protein 5
107d1gp1a_
not modelled 99.2 10 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
108d1meka_
not modelled 99.2 21 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:PDI-like
109c3kcmC_
not modelled 99.2 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:thioredoxin family protein;
PDBTitle: the crystal structure of thioredoxin protein from geobacter2 metallireducens
110c3fw2A_
not modelled 99.2 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:thiol-disulfide oxidoreductase;
PDBTitle: c-terminal domain of putative thiol-disulfide oxidoreductase from2 bacteroides thetaiotaomicron.
111d2c0ga2
not modelled 99.2 18 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:ERP29 N domain-like
112c2dj0A_
not modelled 99.2 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:thioredoxin-related transmembrane protein 2;
PDBTitle: the solution structure of the thioredoxin domain of human2 thioredoxin-related transmembrane protein 2
113c2obiA_
not modelled 99.2 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:phospholipid hydroperoxide glutathione
PDBTitle: crystal structure of the selenocysteine to cysteine mutant2 of human phospholipid hydroperoxide glutathione peroxidase3 (gpx4)
114d2b5ea4
not modelled 99.2 15 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:PDI-like
115c2dj1A_
not modelled 99.1 21 PDB header:isomerase
Chain: A: PDB Molecule:protein disulfide-isomerase a4;
PDBTitle: the solution structure of the first thioredoxin domain of2 mouse protein disulfide-isomerase a4
116d1j08a1
not modelled 99.1 11 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:PDI-like
117d1a8la1
not modelled 99.1 13 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:PDI-like
118c3ha9A_
not modelled 99.1 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized thioredoxin-like protein;
PDBTitle: the 1.7a crystal structure of a thioredoxin-like protein from2 aeropyrum pernix
119c3fkfC_
not modelled 99.1 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:thiol-disulfide oxidoreductase;
PDBTitle: thiol-disulfide oxidoreductase from bacteroides fragilis nctc 9343
120c2r37A_
not modelled 99.1 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:glutathione peroxidase 3;
PDBTitle: crystal structure of human glutathione peroxidase 3 (selenocysteine to2 glycine mutant)

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0