Job Description P26616 Confidence 100.00% Date Thu Jan 5 11:43:01 GMT 2012 Rank 4 Aligned Residues 527 % Identity 43% Template c2aw5A_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:nadp-dependent malic enzyme; PDBTitle: crystal structure of a human malic enzyme Resolution 2.50 Å

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		17	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	P	V	L	L	E	F	P	L	L	N	K	G	S	A	F	S	M	E	E	R	R	N	F	N	L	L	G	L	L	P	E	V	V	E	T	I	E	E	Q	A	E	R	A	W	I	Q	Y	Q	G	F	K	T	E	I	D	K	H	I	Y	L	R	N	I	Q	D	T	N	E	T	L	F	Y	R	L	V	N	N	H	L
Query Conservation
Alig confidence																																																																														.
Template Conservation																																																																														.
Template Sequence		G	Y	L	L	T	R	N	P	H	L	N	K	D	L	A	F	T	L	E	E	R	Q	Q	L	N	I	H	G	L	L	P	P	S	F	N	S	Q	E	I	Q	V	L	R	V	V	K	N	F	E	H	L	N	S	D	F	D	R	Y	L	L	L	M	D	L	Q	D	R	N	E	K	L	F	Y	R	V	L	.	T	S	I
Template Known Secondary structure									T	T	T			G	G	G	S								T	T		T	T	T	S		S																			S	S																									.
Template Predicted Secondary structure																																																																														.
Template SS confidence
		15	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90		.	.	.
		97	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	E	M	M	P	V	I	Y	T	P	T	V	G	A	A	C	E	R	F	S	E	I	Y	R	R	S	R	G	V	F	I	S	Y	Q	N	R	H	N	M	D	D	I	L	Q	N	V	P	N	H	N	I	K	V	I	V	V	T	D	G	E	R	I	L	G	L	G	D	Q	G	I	G	G	M	G	I	P	I	G	K	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	K	F	M	P	I	V	Y	T	P	T	V	G	L	A	C	Q	Q	Y	S	L	V	F	R	K	P	R	G	L	F	I	T	I	H	D	R	G	H	I	A	S	V	L	N	A	W	P	E	D	V	I	K	A	I	V	V	T	D	G	E	R	I	L	G	L	G	D	L	G	C	N	G	M	G	I	P	V	G	K	L
Template Known Secondary structure		T	T	T					S	T	T								T							S			S					G	G	G	T	T							T	T	S	S		S										S	S		B	T	T	T	B			G	G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		95	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.
		177	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
Predicted Secondary structure																																																																	.
Query SS confidence																																																																	.
Query Sequence		S	L	Y	T	A	C	G	G	I	S	P	A	Y	T	L	P	V	V	L	D	V	G	T	N	N	Q	Q	L	L	N	D	P	L	Y	M	G	W	R	N	P	R	I	T	D	D	E	Y	Y	E	F	V	D	E	F	I	Q	A	V	K	Q	R	W	P	.	D	V	L	L	Q	F	E	D	F	A	Q	K	N	A	M	P
Query Conservation																																																																	.
Alig confidence																																																																	.
Template Conservation
Template Sequence		A	L	Y	T	A	C	G	G	M	N	P	Q	E	C	L	P	V	I	L	D	V	G	T	E	N	E	E	L	L	K	D	P	L	Y	I	G	L	R	Q	R	R	V	R	G	S	E	Y	D	D	F	L	D	E	F	M	E	A	V	S	S	K	Y	G	M	N	C	L	I	Q	F	E	D	F	A	N	V	N	A	F	R
Template Known Secondary structure												G	G	G																			T	T			S		S	S																									T	T							S
Template Predicted Secondary structure
Template SS confidence
		175	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.
		256	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	L	N	R	Y	R	N	E	I	C	S	F	N	D	D	I	Q	G	T	A	A	V	T	V	G	T	L	I	A	A	S	R	A	A	G	G	Q	L	S	E	K	K	I	V	F	L	G	A	G	S	A	G	C	G	I	A	E	M	I	I	S	Q	T	Q	R	E	G	L	S	E	E	A	A	R	Q	K	V	F	M	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	L	N	K	Y	R	N	Q	Y	C	T	F	N	D	D	I	Q	G	T	A	S	V	A	V	A	G	L	L	A	A	L	R	I	T	K	N	K	L	S	D	Q	T	I	L	F	Q	G	A	G	E	A	A	L	G	I	A	H	L	I	V	M	A	L	E	K	E	G	L	P	K	E	K	A	I	K	K	I	W	L	V
Template Known Secondary structure							T	T	T	S	S				T	T	T																			T	S		G	G	G							B		S																		T								T	T
Template Predicted Secondary structure
Template SS confidence
		255	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.
		336	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	R	F	G	L	L	T	D	K	M	P	N	L	L	P	F	Q	T	K	L	V	Q	K	R	E	N	L	S	D	W	D	T	D	S	D	V	L	S	L	L	D	V	V	R	N	V	K	P	D	I	L	I	G	V	S	G	Q	T	G	L	F	T	E	E	I	I	R	E	M	H	K	H	C	P	R	P	I	V	M	P
Query Conservation
Alig confidence													.	.	.	.	.													.	.	.	.	.	.	.	.	.
Template Conservation													.	.	.	.	.													.	.	.	.	.	.	.	.	.
Template Sequence		D	S	K	G	L	I	V	K	G	Q	E	.	.	.	.	.	K	E	K	F	A	H	E	H	E	E	M	K	.	.	.	.	.	.	.	.	.	N	L	E	A	I	V	Q	E	I	K	P	T	A	L	I	G	V	A	A	I	G	G	A	F	S	E	Q	I	L	K	D	M	A	A	F	N	E	R	P	I	I	F	A
Template Known Secondary structure			T	T				B					.	.	.	.	.	G	G	G	G		B	S						.	.	.	.	.	.	.	.	.												S						S	S		T	T		S													S	S
Template Predicted Secondary structure													.	.	.	.	.													.	.	.	.	.	.	.	.	.
Template SS confidence
		335	.	.	.	.	340	.	.	.	.	.						.	.	.	.	350	.	.	.	.	.	.	.										.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
		416	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.		.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.
Predicted Secondary structure																																						.
Query SS confidence																																						.
Query Sequence		L	S	N	P	T	S	R	V	E	A	T	P	Q	D	I	I	A	W	T	E	G	N	A	L	V	A	T	G	S	P	F	N	P	V	V	W	.	K	D	K	I	Y	P	I	A	Q	C	N	N	A	F	I	F	P	G	I	G	L	G	V	I	A	S	G	A	S	R	I	T	D	E	M	L	M	S	A	S	E	T	L
Query Conservation																																						.
Alig confidence																																						.
Template Conservation
Template Sequence		L	S	N	P	T	S	K	A	E	C	S	A	E	Q	C	Y	K	I	T	K	G	R	A	I	F	A	S	G	S	P	F	D	P	V	T	L	P	N	G	Q	T	L	Y	P	G	Q	G	N	N	S	Y	V	F	P	G	V	A	L	G	V	V	A	C	G	L	R	Q	I	T	D	N	I	F	L	T	T	A	E	V	I
Template Known Secondary structure				S	S	G	G	G		S	S									T	T	T							S	S								T	T	S										G	G	G	T												T		S	S
Template Predicted Secondary structure
Template SS confidence
		406	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.
		495	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.		.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.
Predicted Secondary structure																																													.
Query SS confidence																																													.
Query Sequence		A	Q	Y	S	P	L	V	L	N	G	E	G	M	V	L	P	E	L	K	D	I	Q	K	V	S	R	A	I	A	F	A	V	G	K	M	A	Q	Q	Q	G	V	A	V	.	K	T	S	A	E	A	L	Q	Q	A	I	D	D	N	F	W	Q	A	E	Y	R
Query Conservation																																													.
Alig confidence																																													.
Template Conservation
Template Sequence		A	Q	Q	V	S	D	K	H	L	E	E	G	R	L	Y	P	P	L	N	T	I	R	D	V	S	L	K	I	A	E	K	I	V	K	D	A	Y	Q	E	K	T	A	T	V	Y	P	E	P	Q	N	K	E	A	F	V	R	S	Q	M	Y	S	T	D	Y	D
Template Known Secondary structure				T	S							T	T		S	S			G	G	G																			T	T				S		S			S									T	S			S	S
Template Predicted Secondary structure
Template SS confidence
		486	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550