Job Description P26616 Confidence 100.00% Date Thu Jan 5 11:43:01 GMT 2012 Rank 7 Aligned Residues 356 % Identity 29% Template c1vl6C_ PDB info PDB header:oxidoreductase Chain: C: PDB Molecule:malate oxidoreductase; PDBTitle: crystal structure of nad-dependent malic enzyme (tm0542) from2 thermotoga maritima at 2.61 a resolution Resolution 2.61 Å

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		88	.	90	.	.	.	.	.	.	.											.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.
Predicted Secondary structure												.	.	.	.	.	.	.	.	.	.
Query SS confidence												.	.	.	.	.	.	.	.	.	.
Query Sequence		F	Y	R	L	V	N	N	H	L	D	.	.	.	.	.	.	.	.	.	.	E	M	M	P	V	I	Y	T	P	T	V	G	A	A	C	E	R	F	S	E	I	Y	R	R	S	R	G	V	F	I	S	Y	Q	N	R	H	N	M	D	D	I	L	Q	N	V	P	N	H	N	I	K	V	I	V	V	T	D	G	E	R
Query Conservation												.	.	.	.	.	.	.	.	.	.
Alig confidence												.	.	.	.	.	.	.	.	.	.																				.	.	.											.	.	.	.	.	.	.	.	.	.					.	.	.	.
Template Conservation																																									.	.	.											.	.	.	.	.	.	.	.	.	.					.	.	.	.
Template Sequence		V	H	R	F	L	K	G	K	I	R	T	A	L	P	V	E	K	V	D	R	E	T	L	S	L	L	Y	T	P	G	V	A	D	V	A	R	A	C	A	.	.	.	E	D	P	E	K	T	Y	V	Y	T	.	.	.	.	.	.	.	.	.	.	S	R	W	N	.	.	.	.	T	V	A	V	V	S	D	G	S	A
Template Known Secondary structure							T		S						S		S											S	T	T	T										.	.	.			G	G	G					S	.	.	.	.	.	.	.	.	.	.	G	G	G	G	.	.	.	.								S	T	T
Template Predicted Secondary structure																																									.	.	.											.	.	.	.	.	.	.	.	.	.					.	.	.	.
Template SS confidence
		6	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.				.	.	.	.	.	50	.	.	.	.											.	.	.	.					.	60	.	.	.	.	.	.	.	.
		158	.	160	.	.	.	.	.	.	.	.		.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Predicted Secondary structure													.
Query SS confidence													.
Query Sequence		I	L	G	L	G	D	Q	G	I	G	G	.	M	G	I	P	I	G	K	L	S	L	Y	T	A	C	G	G	I	S	P	A	Y	T	L	P	V	V	L	D	V	G	T	N	N	Q	Q	L	L	N	D	P	L	Y	M	G	W	R	N	P	R	I	T	D	D	E	Y	Y	E	F	V	D	E	F	I	Q	A	V	K	Q
Query Conservation													.
Alig confidence													.																			.	.	.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																.	.	.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	L	G	L	G	N	I	G	P	Y	G	A	L	P	V	X	E	G	K	A	F	L	F	K	A	F	A	D	I	D	.	.	.	A	F	P	I	C	L	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	S	E	E	E	K	I	I	S	I	V	K	S	L	E	P
Template Known Secondary structure		B	T	T	T	B	S																									.	.	.							S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														T	G	G
Template Predicted Secondary structure																																.	.	.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		69	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.				.	100	.	.	.	.	.																									.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.			.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.
Predicted Secondary structure																													.	.
Query SS confidence																													.	.
Query Sequence		R	W	P	D	V	L	L	Q	F	E	D	F	A	Q	K	N	A	M	P	L	L	N	R	Y	R	N	E	.	.	I	C	S	F	N	D	D	I	Q	G	T	A	A	V	T	V	G	T	L	I	A	A	S	R	A	A	G	G	Q	L	S	E	K	K	I	V	F	L	G	A	G	S	A	G	C	G	I	A	E	M	I
Query Conservation																													.	.
Alig confidence						.	.																						.	.
Template Conservation						.	.
Template Sequence		S	F	G	G	.	.	I	N	L	E	D	I	G	A	P	K	C	F	R	I	L	Q	R	L	S	E	E	X	N	I	P	V	F	H	D	D	Q	Q	G	T	A	V	V	V	S	A	A	F	L	N	A	L	K	L	T	E	K	K	I	E	E	V	K	V	V	V	N	G	I	G	A	A	G	Y	N	I	V	K	F	L
Template Known Secondary structure		G		S		.	.					S			T	T														S	S																										T			G	G	G									S
Template Predicted Secondary structure						.	.
Template SS confidence
		122	.	.	.			.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
		315	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.			.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
Predicted Secondary structure																																			.	.
Query SS confidence																																			.	.
Query Sequence		I	S	Q	T	Q	R	E	G	L	S	E	E	A	A	R	Q	K	V	F	M	V	D	R	F	G	L	L	T	D	K	M	P	N	.	.	L	L	P	F	Q	T	K	L	V	Q	K	R	E	N	L	S	D	W	D	T	D	S	D	V	L	S	L	L	D	V	V	R	N	V	K	P	D	I	L	I	G	V	S	G	Q
Query Conservation																																			.	.
Alig confidence			.	.	.	.	.	.	.	.	.	.																							.	.												.	.	.	.	.	.																.	.											.
Template Conservation			.	.	.	.	.	.	.	.	.	.																																				.	.	.	.	.	.																.	.											.
Template Sequence		L	.	.	.	.	.	.	.	.	.	.	D	L	G	V	K	N	V	V	A	V	D	R	K	G	I	L	N	E	N	D	P	E	T	C	L	N	E	Y	H	L	E	I	A	R	I	.	.	.	.	.	.	T	N	P	E	R	L	S	G	D	L	E	T	A	L	E	.	.	G	A	D	F	F	I	G	V	S	R	.
Template Known Secondary structure			.	.	.	.	.	.	.	.	.	.			T		S							T	T					T	T	S	G	G	G		S	S									T	.	.	.	.	.	.	S		T	T				S							T	.	.	T		S						S		.
Template Predicted Secondary structure			.	.	.	.	.	.	.	.	.	.																																				.	.	.	.	.	.																.	.											.
Template SS confidence
		200											.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.							.	.	.	.	240	.	.	.	.	.	.	.	.	.	250			.	.	.	.	.	.	.	.	.	260
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	G	L	F	T	E	E	I	I	R	E	M	H	K	H	C	P	R	P	I	V	M	P	L	S	N	P	T	S	R	V	E	A	T	P	Q	D	I	I	A	W	T	E	G	N	A	L	V	A	T	G	S	P	F	N	P	V	V	W	K	D	K	I	Y	P	I	A	Q	C	N	N	A	F	I	F	P	G	I	G	L
Query Conservation
Alig confidence										.	.	.																			.	.								.	.																	.	.	.	.	.	.	.	.	.	.
Template Conservation										.	.	.																			.	.								.	.																	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	N	I	L	K	P	E	W	.	.	.	I	K	K	X	S	R	K	P	V	I	F	A	L	A	N	P	V	P	.	.	E	I	D	P	E	L	A	.	.	R	E	A	G	A	F	I	V	A	T	G	R	S	D	H	P	.	.	.	.	.	.	.	.	.	.	N	Q	V	N	N	L	L	A	F	P	G	I	X	K
Template Known Secondary structure		S	S		S					.	.	.		T	T	S		S	S								S	S	S		.	.	S	S						.	.			T	T		S					S		T	T	S	S	.	.	.	.	.	.	.	.	.	.	S	B			G	G	G	T
Template Predicted Secondary structure										.	.	.																			.	.								.	.																	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		261	.	.	.	.	.	.	.				.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.			.	.	.	290	.	.	.			.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.											310	.	.	.	.	.	.	.	.	.	320	.	.	.
		473	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530
Predicted Secondary structure
Query SS confidence
Query Sequence		G	V	I	A	S	G	A	S	R	I	T	D	E	M	L	M	S	A	S	E	T	L	A	Q	Y	S	P	L	V	L	N	G	E	G	M	V	L	P	E	L	K	D	I	Q	K	V	S	R	A	I	A	F	A	V	G	K	M	A
Query Conservation
Alig confidence										.																						.	.	.												.
Template Conservation										.																						.	.	.												.
Template Sequence		G	A	V	E	K	R	S	K	.	I	T	K	N	X	L	L	S	A	V	E	A	I	A	R	S	C	E	P	E	P	.	.	.	E	R	I	I	P	E	A	F	D	X	K	.	V	H	L	N	V	Y	T	A	V	K	G	S	A
Template Known Secondary structure								S		.																T	S			B	T	.	.	.	T	B	S	S			T	T				.												T
Template Predicted Secondary structure										.																						.	.	.												.
Template SS confidence
		324	.	.	.	.	.	330	.		.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.				.	.	.	.	.	.	.	360	.	.	.		.	.	.	.	.	.	370	.	.	.	.	.	.