Job Description P26616 Confidence 100.00% Date Thu Jan 5 11:43:01 GMT 2012 Rank 2 Aligned Residues 546 % Identity 41% Template c1gz3B_ PDB info PDB header:oxidoreductase Chain: B: PDB Molecule:nad-dependent malic enzyme; PDBTitle: molecular mechanism for the regulation of human mitochondrial2 nad(p)+-dependent malic enzyme by atp and fumarate Resolution 2.3 Å

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		12	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	I	P	Y	A	G	P	V	L	L	E	F	P	L	L	N	K	G	S	A	F	S	M	E	E	R	R	N	F	N	L	L	G	L	L	P	E	V	V	E	T	I	E	E	Q	A	E	R	A	W	I	Q	Y	Q	G	F	K	T	E	I	D	K	H	I	Y	L	R	N	I	Q	D	T	N	E	T	L	F	Y	R	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	I	K	E	K	G	K	P	L	M	L	N	P	R	T	N	K	G	M	A	F	T	L	Q	E	R	Q	M	L	G	L	Q	G	L	L	P	P	K	I	E	T	Q	D	I	Q	A	L	R	F	H	R	N	L	K	K	M	T	S	P	L	E	K	Y	I	Y	I	M	G	I	Q	E	R	N	E	K	L	F	Y	R	I
Template Known Secondary structure				S			S	T					S	T	T	T			G	G	G	S									T		T	T	T	S		S																		T																T	T
Template Predicted Secondary structure
Template SS confidence
		20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.
		92	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	N	N	H	L	D	E	M	M	P	V	I	Y	T	P	T	V	G	A	A	C	E	R	F	S	E	I	Y	R	R	S	R	G	V	F	I	S	Y	Q	N	R	H	N	M	D	D	I	L	Q	N	V	P	N	H	N	I	K	V	I	V	V	T	D	G	E	R	I	L	G	L	G	D	Q	G	I	G	G	M	G	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	Q	D	D	I	E	S	L	M	P	I	V	Y	T	P	T	V	G	L	A	C	S	Q	Y	G	H	I	F	R	R	P	K	G	L	F	I	S	I	S	D	R	G	H	V	R	S	I	V	D	N	W	P	E	N	H	V	K	A	V	V	V	T	D	G	E	R	I	L	G	L	G	D	L	G	V	Y	G	M	G	I
Template Known Secondary structure														S	T	T								T						S	S			S					G	G	G	T	T							T	T		S		S										S	S	S	B	T	T	T	B			G	G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.
		172	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.		240	.	.	.	.	.	.	.	.	.	250
Predicted Secondary structure																																																																						.
Query SS confidence																																																																						.
Query Sequence		P	I	G	K	L	S	L	Y	T	A	C	G	G	I	S	P	A	Y	T	L	P	V	V	L	D	V	G	T	N	N	Q	Q	L	L	N	D	P	L	Y	M	G	W	R	N	P	R	I	T	D	D	E	Y	Y	E	F	V	D	E	F	I	Q	A	V	K	Q	R	W	P	.	D	V	L	L	Q	F	E	D	F	A	Q
Query Conservation																																																																						.
Alig confidence																																																																						.
Template Conservation
Template Sequence		P	V	G	K	L	C	L	Y	T	A	C	A	G	I	R	P	D	Q	C	L	P	V	C	I	D	V	G	T	D	N	I	A	L	L	K	D	P	F	Y	M	G	L	Y	Q	K	R	D	R	T	Q	Q	Y	D	D	L	I	D	E	F	M	K	A	I	T	D	R	Y	G	R	N	T	L	I	Q	F	E	D	F	G	N
Template Known Secondary structure																	G	G	G								S									T		T	T			S		S	S					S																				T	T							S
Template Predicted Secondary structure
Template SS confidence
		180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
		251	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330
Predicted Secondary structure
Query SS confidence
Query Sequence		K	N	A	M	P	L	L	N	R	Y	R	N	E	I	C	S	F	N	D	D	I	Q	G	T	A	A	V	T	V	G	T	L	I	A	A	S	R	A	A	G	G	Q	L	S	E	K	K	I	V	F	L	G	A	G	S	A	G	C	G	I	A	E	M	I	I	S	Q	T	Q	R	E	G	L	S	E	E	A	A	R	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	N	A	F	R	F	L	R	K	Y	R	E	K	Y	C	T	F	N	D	D	I	Q	G	T	A	A	V	A	L	A	G	L	L	A	A	Q	K	V	I	S	K	P	I	S	E	H	K	I	L	F	L	G	A	G	E	A	A	L	G	I	A	N	L	I	V	M	S	M	V	E	N	G	L	S	E	Q	E	A	Q	K
Template Known Secondary structure												T	T	T	S	S				T	T	T	T																					T	T	T									S																	T	T
Template Predicted Secondary structure
Template SS confidence
		260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.
		331	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.		.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																			.
Query SS confidence																			.
Query Sequence		K	V	F	M	V	D	R	F	G	L	L	T	D	K	M	P	N	.	L	L	P	F	Q	T	K	L	V	Q	K	R	E	N	L	S	D	W	D	T	D	S	D	V	L	S	L	L	D	V	V	R	N	V	K	P	D	I	L	I	G	V	S	G	Q	T	G	L	F	T	E	E	I	I	R	E	M	H	K	H	C	P
Query Conservation																			.
Alig confidence																			.												.	.	.	.	.	.	.
Template Conservation																															.	.	.	.	.	.	.
Template Sequence		K	I	W	M	F	D	K	Y	G	L	L	V	K	G	R	K	A	K	I	D	S	Y	Q	E	P	F	T	H	S	.	.	.	.	.	.	.	A	P	E	S	I	P	D	T	F	E	D	A	V	N	I	L	K	P	S	T	I	I	G	V	A	G	A	G	R	L	F	T	P	D	V	I	R	A	M	A	S	I	N	E
Template Known Secondary structure		T						T	T				B	T	T		S	S				T	T	T	G	G	G		B		.	.	.	.	.	.	.			S	S			S	S											S							S	S	S			S													S
Template Predicted Secondary structure																															.	.	.	.	.	.	.
Template SS confidence
		340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.								.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.
		410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.		.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.
Predicted Secondary structure																																												.
Query SS confidence																																												.
Query Sequence		R	P	I	V	M	P	L	S	N	P	T	S	R	V	E	A	T	P	Q	D	I	I	A	W	T	E	G	N	A	L	V	A	T	G	S	P	F	N	P	V	V	W	.	K	D	K	I	Y	P	I	A	Q	C	N	N	A	F	I	F	P	G	I	G	L	G	V	I	A	S	G	A	S	R	I	T	D	E	M	L	M
Query Conservation																																												.
Alig confidence																																												.
Template Conservation
Template Sequence		R	P	V	I	F	A	L	S	N	P	T	A	Q	A	E	C	T	A	E	E	A	Y	T	L	T	E	G	R	C	L	F	A	S	G	S	P	F	G	P	V	K	L	T	D	G	R	V	F	T	P	G	Q	G	N	N	V	Y	I	F	P	G	V	A	L	A	V	I	L	C	N	T	R	H	I	S	D	S	V	F	L
Template Known Secondary structure		S								S	S	G	G	G	S	S	S									T	T	T							S	S								T	T	S										G	G	G	T											T	T		S
Template Predicted Secondary structure
Template SS confidence
		413	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.
		489	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.		.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.
Predicted Secondary structure																																																			.
Query SS confidence																																																			.
Query Sequence		S	A	S	E	T	L	A	Q	Y	S	P	L	V	L	N	G	E	G	M	V	L	P	E	L	K	D	I	Q	K	V	S	R	A	I	A	F	A	V	G	K	M	A	Q	Q	Q	G	V	A	V	.	K	T	S	A	E	A	L	Q	Q	A	I	D	D	N	F	W	Q	A	E	Y	R	D	Y	R	R	T	S
Query Conservation																																																			.
Alig confidence																																																			.
Template Conservation
Template Sequence		E	A	A	K	A	L	T	S	Q	L	T	D	E	E	L	A	Q	G	R	L	Y	P	P	L	A	N	I	Q	E	V	S	I	N	I	A	I	K	V	T	E	Y	L	Y	A	N	K	M	A	F	V	Y	P	E	P	E	D	K	A	K	Y	V	K	E	Q	T	W	R	S	E	Y	D	S	L	L	P	D	V
Template Known Secondary structure									T	T								T	T		S	S			G	G	G																			T	T					S	S			S														S
Template Predicted Secondary structure
Template SS confidence
		493	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.