Job Description P45475 Confidence 89.26% Date Thu Jan 5 12:02:49 GMT 2012 Rank 103 Aligned Residues 130 % Identity 12% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.									.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.
Predicted Secondary structure																																				.	.	.	.	.	.	.	.																																		.	.	.	.	.
Query SS confidence																																				.	.	.	.	.	.	.	.																																		.	.	.	.	.
Query Sequence		L	G	P	V	L	W	Y	W	P	K	E	T	L	E	E	F	Y	Q	Q	A	A	T	S	S	A	D	V	I	Y	L	G	E	A	V	.	.	.	.	.	.	.	.	C	S	K	R	R	A	T	K	V	G	D	W	L	E	M	A	K	S	L	A	G	S	G	K	Q	I	V	L	S	T	L	A	L	.	.	.	.	.
Query Conservation																																				.	.	.	.	.	.	.	.																																		.	.	.	.	.
Alig confidence																						.														.	.	.	.	.	.	.	.																																		.	.	.	.	.
Template Conservation																						.
Template Sequence		F	P	G	I	N	Y	P	V	L	T	P	N	L	K	G	F	E	A	A	V	.	A	A	G	A	K	E	V	V	I	F	G	A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y
Template Known Secondary structure			T	T		B							S									.		T	T		S								S									T	S	S		T	T	T															T	T									S	T	T		B	T	T
Template Predicted Secondary structure																						.
Template SS confidence
		98	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.		.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.
					72	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.											.	.	100	.	.	.	.	.			.	.	.	.	110					.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.
Predicted Secondary structure		.	.	.																											.	.	.	.	.	.	.	.	.	.									.	.						.	.	.	.
Query SS confidence		.	.	.																											.	.	.	.	.	.	.	.	.	.									.	.						.	.	.	.
Query Sequence		.	.	.	V	Q	A	S	S	E	L	G	E	L	K	R	Y	V	E	N	G	E	F	L	I	E	A	S	D	L	.	.	.	.	.	.	.	.	.	.	G	V	V	N	M	C	A	E	.	.	R	K	L	P	F	.	.	.	.	V	A	G	H	A	L	N	C	Y	N	A	V	T	L	K	I	L	L	K	Q	G	M
Query Conservation		.	.	.																											.	.	.	.	.	.	.	.	.	.									.	.						.	.	.	.
Alig confidence		.	.	.																											.	.	.	.	.	.	.	.	.	.									.	.						.	.	.	.																.	.	.
Template Conservation																																																																											.	.	.
Template Sequence		E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	I	S	L	G	D	T	I	G	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	.	.	.	Q	M	G	V
Template Known Secondary structure		T	B	S																T	T		S							T	T																			S		G	G	G						B		T	T	S											.	.	.		T	T
Template Predicted Secondary structure																																																																											.	.	.
Template SS confidence
		177	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.				250	.	.	.
		133	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	R	W	C	M	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	V	V	D	S	S
Template Known Secondary structure							B
Template Predicted Secondary structure
Template SS confidence
		254	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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