Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	V	T	S	K	K	M	T	A	A	V	L	A	I	T	L	A	M	S	L	S	A	C	S	N	W	S	K	R	D	R	N	T	A	I	G	A	G	A	G	A	L	G	G	A	V	L	T	D	G	S	T	L	G	T	L	G	G	A
Secondary structure
SS confidence
Disorder		?	?	?	?																		?	?	?	?	?	?	?	?	?	?	?	?	?															?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.
Sequence		A	V	G	G	V	I	G	H	Q	V	G	K
Secondary structure
SS confidence
Disorder											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2lbg chain A Region: 35 - 48 Aligned: 14 Modelled: 14 Confidence: 28.5% Identity: 57% PDB header:membrane protein Chain: A: PDB Molecule:major prion protein; PDBTitle: structure of the chr of the prion protein in dpc micelles Phyre2 PDB 2onf chain A domain 1 Region: 16 - 28 Aligned: 13 Modelled: 13 Confidence: 9.1% Identity: 15% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1ml8 chain A Region: 16 - 28 Aligned: 13 Modelled: 13 Confidence: 9.1% Identity: 23% Fold: OsmC-like Superfamily: OsmC-like Family: YhfA-like Phyre2 PDB 2bjo chain A Region: 16 - 28 Aligned: 13 Modelled: 13 Confidence: 8.9% Identity: 23% PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein ohrb; PDBTitle: crystal structure of the organic hydroperoxide resistance2 protein ohrb of bacillus subtilis Phyre2 PDB 1vla chain A Region: 16 - 28 Aligned: 13 Modelled: 11 Confidence: 7.4% Identity: 15% Fold: OsmC-like Superfamily: OsmC-like Family: YhfA-like Phyre2 PDB 1i4m chain A Region: 37 - 48 Aligned: 12 Modelled: 12 Confidence: 6.7% Identity: 58% Fold: Prion-like Superfamily: Prion-like Family: Prion-like Phyre2 PDB 1lql chain A Region: 16 - 28 Aligned: 13 Modelled: 13 Confidence: 6.3% Identity: 31% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1lql chain E Region: 16 - 28 Aligned: 13 Modelled: 13 Confidence: 6.3% Identity: 31% PDB header:unknown function Chain: E: PDB Molecule:osmotical inducible protein c like family; PDBTitle: crystal structure of osmc like protein from mycoplasma2 pneumoniae Phyre2 PDB 2egt chain A Region: 16 - 28 Aligned: 13 Modelled: 13 Confidence: 5.8% Identity: 31% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein aq_1549; PDBTitle: crystal structure of hypothetical protein (aq1549) from aquifex2 aeolicus Phyre2 PDB 1n2f chain A Region: 16 - 28 Aligned: 13 Modelled: 13 Confidence: 5.6% Identity: 31% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 2pn2 chain A domain 1 Region: 16 - 28 Aligned: 13 Modelled: 12 Confidence: 5.3% Identity: 38% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1nye chain D Region: 16 - 28 Aligned: 13 Modelled: 13 Confidence: 5.3% Identity: 15% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 1 c2lbgA_ 2 d2onfa1 3 d1ml8a_ 4 c2bjoA_ 5 d1vlaa_ 6 d1i4ma_ 7 d1lqla_ 8 c1lqlE_ 9 c2egtA_ 10 d1n2fa_ 11 d2pn2a1 12 d1nyed_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2lbgA_ 28.5 57 PDB header:membrane protein Chain: A: PDB Molecule:major prion protein; PDBTitle: structure of the chr of the prion protein in dpc micelles 2 d2onfa1 9.1 15 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 3 d1ml8a_ 9.1 23 Fold:OsmC-like Superfamily:OsmC-like Family:YhfA-like 4 c2bjoA_ 8.9 23 PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein ohrb; PDBTitle: crystal structure of the organic hydroperoxide resistance2 protein ohrb of bacillus subtilis 5 d1vlaa_ 7.4 15 Fold:OsmC-like Superfamily:OsmC-like Family:YhfA-like 6 d1i4ma_ 6.7 58 Fold:Prion-like Superfamily:Prion-like Family:Prion-like 7 d1lqla_ 6.3 31 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 8 c1lqlE_ 6.3 31 PDB header:unknown function Chain: E: PDB Molecule:osmotical inducible protein c like family; PDBTitle: crystal structure of osmc like protein from mycoplasma2 pneumoniae 9 c2egtA_ 5.8 31 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein aq_1549; PDBTitle: crystal structure of hypothetical protein (aq1549) from aquifex2 aeolicus 10 d1n2fa_ 5.6 31 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 11 d2pn2a1 5.3 38 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 12 d1nyed_ 5.3 15 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0