|   |
26 | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
V | K | I | G | M | A | I | D | D | L | R | L | E | R | W | Q | K | D | R | D | I | F | V | K | K | A | E | S | L | G | A | K | V | F | V | Q | S | A | N | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | E | E | T |
Query Conservation |   |
  |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |
|
|
|   |
|
|
|   |
|
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | R | I | G | I | L | T | S | G | G | D | A | P | G | M | N | A | A | V | R | A | V | T | R | V | A | I | A | N | G | L | E | V | F | G | I | R | Y | G | F | A | G | L | V | A | G | D | I | F | P | L | E | S | E | D | V | A | H | L | I | N | V | S | G | T | F | L | Y | S | A | R | Y | P | E | F | A | E | E | E | G |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
| S | S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |
| T |  |  |  |  |  |  |  | T |
|  |  |  |
|
| G | G | G | G | T | T |
| T | T |
|
| S |
| T | T |
|
|
|
|
| G | G | G | T | S |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | |
|
|
|
. | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | M | S | Q | I | E | N | M | I | N | R | G | V | D | V | L | V | I | I | P | Y | N | G | Q | V | L | S | N | V | V | K | E | A | K | Q | E | G | I | K | V | L | A | Y | . |
. |
. |
. |
D | R | M | I | N | D | A | D | I | D | F | Y | I | S | F | D | N | E | K | V | G | E | L | Q | A | K | A | L | V | D | I | V | P |
Query Conservation |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|   |
|
|   | . | . |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|
Template Sequence |   |
Q | L | A | G | I | E | Q | L | K | K | H | G | I | D | A | V | V | V | I | G | G | D | G | S | Y | . |
. |
H | G | A | L | Q | L | T | R | H | G | F | N | S | I | G | L | P | G | T | I | D | N | D | I | P | Y | T | D | A | T | I | G | Y | D | T | A | C | M | T | A | M | D | A | I | D | K | I | R | D | T | A | S | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |
|  |  |  |  | . | . |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  | T | T |
|
|
| T | T |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | |
|
. | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | G | N | Y | F | L | M | G | G | S | P | V | D | N | N | A | K | L | F | R | A | G | Q | M | K | V | L | K | P | Y | V | D | S | G | K | I | K | V | V | G | D | Q | W | V | D | G | W | L | P | E | N | A | L | K | I | M | E | N | A | L | T | A | N | N | N | K | I | D | A | V | V | A | S | N | D | A | T | A | G | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
|
|
|
|
|
|   | . | . | . | . | . | . | . |   |
|   |
|
|   |   |   |
|
|
|   |   |
|
|   |
|
|
|
|
|   |   |   | . | . | . |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|
|
|   |   |   |   |   |   |
Template Sequence |   |
H | H | R | V | F | I | V | N | V | M | G | R | N | . |
. |
. |
. |
. |
. |
. |
C | G | D | I | A | M | R | V | G | V | A | C | G | A | D | A | I | V | I | P | E | R | P | Y | . |
. |
. |
D | V | E | E | I | A | N | R | L | K | Q | A | Q | E | S | G | K | D | H | G | L | V | V | V | A | E | G | V | M | T | A | D | Q |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |  |  |
|
| T | T | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |
| T | T | S |
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  | T | T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
|
|
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
  |
  |   |
226 | . | . | . | 230 | . | . | . | |
. | . | . | . | . | . | 240 | . | . | . | . | |
|
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
| . |
|
|
|
|
|
|  |  |  |  |  | . | . | . |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | Q | A | L | S | A | Q | . |
G | L | S | G | K | V | A | I | S | G | Q | . |
. |
. |
D | A | D | L | A | G | I | K | R | I | A | A | G | T | Q | T | M | T | V | Y | K | P | I | T | L | L | A | N | T | A | A | E | I | A | V | E |
Query Conservation |   |
|   |   |
|
|   |   |   | . |
|   |   |   |   |
|   |
|   |
|   | . | . | . |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |
|
|   |   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |
|
|   |   |   |   |   |
Template Sequence |   |
F | M | A | E | L | K | K | Y | G | D | F | D | V | R | A | N | V | L | G | H | M | Q | R | G | G | T | P | T | V | S | D | R | V | L | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | K | L | G | S | E | A | V | H | L | L | L | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | S | S |
|
|
|  |  |  |  |  |
| G | G | G | G | G |
| S |
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 270 | . | . | . | . | . | . | . |
  |