Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	S	F	S	T	L	L	S	V	H	L	I	S	I	A	L	S	V	G	L	L	T	L	R	F	W	L	R	Y	Q	K	H	P	Q	A	F	A	R	W	T	R	I	V	P	P	V	V	D	T	L	L	L	L	S	G	I	A	L	M
Secondary structure
SS confidence
Disorder		?	?	?																													?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	K	A	H	I	L	P	F	S	G	Q	A	Q	W	L	T	E	K	L	F	G	V	I	I	Y	I	V	L	G	F	I	A	L	D	Y	R	R	M	H	S	Q	Q	A	R	I	I	A	F	P	L	A	L	V	V	L	Y	I	I	I	K
Secondary structure
SS confidence
Disorder								?				?																						?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130
Sequence		L	A	T	T	K	V	P	L	L	G
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1fft chain B domain 2 Region: 79 - 101 Aligned: 23 Modelled: 23 Confidence: 5.7% Identity: 13% Fold: Transmembrane helix hairpin Superfamily: Cytochrome c oxidase subunit II-like, transmembrane region Family: Cytochrome c oxidase subunit II-like, transmembrane region Phyre2 PDB 1s7b chain A Region: 87 - 128 Aligned: 42 Modelled: 42 Confidence: 5.4% Identity: 7% Fold: Multidrug resistance efflux transporter EmrE Superfamily: Multidrug resistance efflux transporter EmrE Family: Multidrug resistance efflux transporter EmrE Phyre2 PDB 3dl8 chain D Region: 103 - 125 Aligned: 23 Modelled: 23 Confidence: 5.3% Identity: 39% PDB header:protein transport Chain: D: PDB Molecule:sece; PDBTitle: structure of the complex of aquifex aeolicus secyeg and2 bacillus subtilis seca Phyre2 1 d1fftb2 2 d1s7ba_ 3 c3dl8D_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1fftb2 5.7 13 Fold:Transmembrane helix hairpin Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region Family:Cytochrome c oxidase subunit II-like, transmembrane region 2 d1s7ba_ 5.4 7 Fold:Multidrug resistance efflux transporter EmrE Superfamily:Multidrug resistance efflux transporter EmrE Family:Multidrug resistance efflux transporter EmrE 3 c3dl8D_ 5.3 39 PDB header:protein transport Chain: D: PDB Molecule:sece; PDBTitle: structure of the complex of aquifex aeolicus secyeg and2 bacillus subtilis seca

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0