|   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
. | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | H | D | G | V | T | G | V | N | T | G | Y | D | D | L | N | K | K | T | . |
A | G | L | Q | P | S | D | L | I | I | V | A | A | R | P | S | M | G | K | T | T | F | A | M | N | L | V | E | N | A | A | M | L | Q | D | K | P | V | L | I | F | S | L | E | M | P | S | E | Q | I | M | M | R | S | L | A | S | L | S | R |
Query Conservation |   |
  |   |   |   |   |   |
|
|   |
|
|   |   |   |
|
|   |   |   | . |
|
|   |   |   |
|   |
|   |
|
|   |
|   |
|
|   |
|
|
|   |
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|   |
|
|
|   |   |
|
|   |   |
|   |
|
|
|   |   |
|   |   |   |
|
|   |
|   |   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   | . |   |   |
|   |   |
|   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
Q | R | S | S | N | V | R | V | S | S | G | V | V | R | L | D | E | M | C | G | G | G | F | F | K | D | S | I | I | L | A | T | G | A | T | G | T | G | K | T | L | L | V | S | R | F | V | E | N | A | C | . |
A | N | K | E | R | A | I | L | F | A | Y | E | E | S | R | A | Q | L | L | R | N | A | Y | S | W | G | M | D |
Template Known Secondary structure |   |
|
|
|
|
|
|  |  |
|
| S |
|  |  |  |  |  |  | T | T | S | S |  |  | S | S |
|  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | T | T |
|
|  |  |  |  |  | S | S | S |
|  |  |  |  |  |  |  |  |  | T | T | S |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
256 | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
. | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
  |
  |   |
279 | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | |
|
. | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | D | Q | T | K | I | R | T | G | Q | L | D | D | E | D | W | A | R | I | S | G | T | M | G | I | L | L | E | K | R | N | I | Y | I | D | D | S | S | . |
. |
G | L | T | P | T | E | V | R | S | R | A | R | R | I | A | R | E | H | G | G | I | G | L | I | M | I | D | Y | L | Q | L | M | R | V | P | A | L | S | D | N |
Query Conservation |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   | . | . |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |   | . | . | . | . |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | E | E | M | E | R | Q | N | L | L | K | I | V | C | A | Y | P | E | S | A | G | L | E | D | H | L | Q | I | I | K | S | E | I | N | D | F | . |
K | P | A | R | I | A | I | D | S | L | S | A | L | A | R | G | . |
. |
. |
. |
V |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  | T | T | S |  |  |  |
|
|
|
| G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . |
|
| S |  |  |  |  |  |
|  |  |  |  | T | S | S | . | . | . | . | S |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
| . | . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | |
. | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
|
|
|
. |
  |
  |   |
357 | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | T | L | E | I | A | E | I | S | R | S | L | K | A | L | A | K | E | L | N | V | P | V | V | A | L | S | Q | L | N | R | S | L | E | Q | R | A | D | K | R | P | V | N | S | D | L | R | E | S | G | S | I | E | Q | D | A | D | L | I | M | F | I | Y | R | D | E | V | Y | H | E | N | S | D | L | K | G | I | A | E | I |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |   |   |   |
|   |
|
|   |
|
|
|
|
|
|   |   |   |   |
|   |   |   |   |
|   |
|   |
|
|   |
|
|   |   |
|   |   |   |
|
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
S | N | N | A | F | R | Q | F | V | I | G | V | T | G | Y | A | K | Q | E | E | I | T | G | L | F | T | N | T | S | D | Q | F | M | G | A | H | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
I | T | D | S | H | I | S | T | I | T | D | T | I | I | L | L | Q | Y | V | E | . |
. |
. |
. |
. |
I | R | G | E | M | S | R | A | I |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |
| S | S | S | S |
|
|
| S | . | . | . | . | . | . | . | . | . | S |
| S | S |
|
| T | T | T |
| S |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  | T | T |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
388 | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 450 | . | . | . |
  |
  |   |
437 | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | I | G | K | Q | R | N | G | P | I | G | T | V | R | L | T | F | N |
Query Conservation |   |
  |
|   |
|
|
|   |
|   |   |
|   |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
N | V | F | K | M | R | G | S | W | H | D | K | A | I | R | E | F | M |
Template Known Secondary structure |   |
 |  |  |  |  | S | S | S |
|
|
|
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
454 | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . |
  |