|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
|
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | S | D | T | V | T | R | P | S | R | A | M | L | E | A | M | M | A | A | P | V | G | D | D | V | Y | G | . |
. |
D | D | P | T | V | N | A | L | Q | D | Y | A | A | E | L | S | G | K | E | A | A | I | F | L | P | T | G | T | Q | A | N | L | V | A | L | L | S | H | C | E | R | G | E | E | Y | I | V | G | Q | A |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   | . | . |   |   |
|   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |   |   |
|
|   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |
|
|   |   |   |
|
|   |
|
|   |   |   |   |
Template Sequence |   |
Y | Q | T | S | T | F | V | F | D | N | C | Q | Q | G | G | N | R | F | A | G | Q | E | S | G | Y | I | Y | T | R | L | G | N | P | T | V | S | N | L | E | G | K | I | A | F | L | E | K | T | E | A | C | V | A | T | S | S | G | M | G | A | I | A | A | T | V | L | T | I | L | K | A | G | D | H | L | I | S | D | E | C |
Template Known Secondary structure |   |
|
|
| S | B |
|
|
| S | S |  |  |  |  |  |  |  |  | T | T | S | S |
| S |
|
| B | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . |
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | |
. | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | H | N | Y | L | F | E | A | G | . |
G | A | A | V | L | G | S | I | Q | P | Q | P | I | D | A | A | A | D | G | T | L | P | L | D | K | V | A | M | K | I | K | P | D | D | I | H | F | A | R | T | K | L | L | S | L | E | N | T | H | N | G | K | V | L | P | R | E | Y | L | K | E | A | W | E | F | T | R | E | R | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |   | . | . | . | . | . |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   | . | . |   |   |   |   |   |
Template Sequence |   |
L | Y | G | C | T | H | A | L | F | E | H | A | L | T | K | F | G | I | Q | V | D | F | I | N | T | A | . |
. |
. |
. |
. |
I | P | G | E | V | K | K | H | M | K | P | N | . |
. |
. |
. |
T | K | I | V | Y | F | E | T | P | A | N | P | T | L | K | I | I | D | M | E | R | V | C | K | D | A | . |
. |
H | S | Q | E | G |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  | T |  |  |  |  | T | T |
|  |  |  |  |  |
| T | T | . | . | . | . | . | S | T | T |  |  |  |  |  |
|
| T | T | . | . | . | . |  |  |  |  |  |  |  | S | S |
| T | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |  | T | S | T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 140 | . | . | . | . | . | . | . | |
|
|
|
. | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | |
|
. | . | . | . | . |
  |
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
|
. | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | L | H | V | D | G | A | R | I | F | N | A | V | V | A | Y | G | C | E | L | K | E | I | T | Q | Y | C | D | S | F | T | I | C | L | S | K | G | L | G | T | P | V | G | . |
. |
. |
S | L | L | V | G | N | R | D | Y | I | K | R | A | I | R | W | R | K | M | T | G | G | G | M | R | Q | S | G | I | L | A | A | A |
Query Conservation |   |
  |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|   |   |   |
|   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
V | L | V | I | A | D | N | T | F | C | S | P | M | I | . |
. |
. |
. |
. |
. |
T | N | P | V | D | F | G | V | D | V | V | V | H | S | A | T | K | Y | I | N | G | H | T | D | V | V | A | G | L | I | C | G | K | A | D | L | L | Q | Q | I | R | M | V | G | I | K | D | I | T | G | S | V | I | S | P | H | D | A | W | L |
Template Known Secondary structure |   |
|  |  |  |  |  |
| T | T | T |
| T | T | T | . | . | . | . | . | . |
|
| G | G | G | G | T |
| S |  |  |  |  |  | T | T | T | T | T | T |
| S | S |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
179 | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
  |
  |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
. | . | . | . | . | 290 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | I | Y | A | L | K | N | N | V | A | R | L | Q | E | D | H | D | N | A | A | W | M | A | E | Q | L | R | E | A | G | A | D | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | R | Q | D | T | N | M | L | F | V | R | V | G | E | . |
. |
E | N | A | A | A | L | G | E | Y | M | K | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . |   |   |   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
I | T | R | G | L | S | T | L | N | I | R | M | K | A | E | S | E | N | A | M | K | V | A | E | Y | L | K | S | H | P | A | V | E | K | V | Y | Y | P | G | F | E | D | H | E | G | H | D | I | A | K | K | Q | M | R | M | Y | G | S | M | I | T | F | I | L | K | S | G | F | E | G | A | K | K | L | L | D | N | L | K | L |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |  |  |  |  |  |
| T | T |
| S | S | S | T | T |  |  |  |  |  |  |  |
| S | S |
|
| S |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . |
  |
  |   |
297 | . | . | 300 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | N | V | L | I | N | A | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | I | V | R | L | V | T | H | L | D | V | S | R | E | Q | L | A | E | V | A | A | H | W | R | A | F | L | A |
Query Conservation |   |
  |
|
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |
|   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |
|
|
|   |   |
|   |   |
|
|   |   |
|   |
|
Template Sequence |   |
I | T | L | A | V | S | L | G | G | C | E | S | L | I | Q | H | P | A | S | M | T | H | A | V | V | P | K | E | E | R | E | A | A | G | I | T | D | G | M | I | R | L | S | V | G | I | E | D | A | D | E | L | I | A | D | F | K | Q | G | L | D | A | L | L | R |
Template Known Secondary structure |   |
S |  |  | S | S |
|
|
| S | S | S |
|  |  |  |
| G | G | G | T | T | T | T | T | S |
|  |  |  |  |  |  | T | T |
|
| T | T |  |  |  |  |  |
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
333 | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . |
  |