|   |
27 | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | |
. | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | D | V | Y | G | D | D | P | T | V | N | A | L | Q | D | Y | A | A | E | L | S | G | K | E | A | A | I | F | L | P | T | G | T | Q | . |
A | N | L | V | A | L | L | S | H | C | E | R | G | E | E | Y | I | V | G | Q | A | A | H | N | Y | L | F | E | A | G | G | A | A | V | L | G | S | I | Q | P | Q | P | I | D | A |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|   | . |
|   |   |   |
|
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |   |
|   |
|   |
|
|
|   |
|
|
|   |   |
|
|
|   |   |
|   |
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |
|
|   |
|
|
|   |
|
|
|
|
|
|
| . | . | . |   |   |
|
|   |
|
|
|
|   |
|
|
|
|   |
|
Template Sequence |   |
G | S | L | L | D | H | S | G | P | H | K | E | A | E | Q | Y | I | A | R | V | F | N | A | D | R | S | Y | M | V | T | N | G | T | S | T | A | N | K | I | V | G | M | Y | S | A | P | A | G | S | T | I | L | I | D | R | N | C | H | K | S | L | . |
. |
. |
T | H | L | M | M | M | S | D | V | T | P | I | Y | F | R | P |
Template Known Secondary structure |   |
| B | T | T | T | T | B | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  | S | S |
|
|  |  |  | . | . | . |  |  |  |  |  |  | S |
|
|  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
|
|
. | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . |
  |
  |   |
106 | |
|
|
|
|
|
|
|
|
|
. | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . |
Predicted Secondary structure |   |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
Query SS confidence |   |
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | D | G | T | L | P | L | D | K | V | A | M | K | I | K | P | D | D | I | H | F | A | R | T | K | L | L | S | L | E | N | T | H | N | G | K | V | L | P | R | E | Y | L | K | E | A | W | E | F | T | R | E | R | N | L | A | L | H | V | D | G | A | R | I | F | N | A | V | V |
Query Conservation |   |
  | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|
|   |   |   |   |
|
|
|
|
|
|
|
|   |
|
|   |   |
| . | . | . |
|   |   |
|   |   |   |   |   |   |   |   | . | . |
|
|
|
|
|
|
|
|
|
|   |   |
|
Template Sequence |   |
T | R | N | A | Y | G | I | L | G | G | I | P | Q | S | E | F | Q | H | A | T | I | A | K | R | V | K | E | T | P | N | A | T | W | P | V | H | A | V | I | T | N | S | T | Y | D | G | L | L | Y | N | . |
. |
. |
T | D | F | I | K | K | T | L | D | V | K | S | . |
. |
I | H | F | D | S | A | W | V | P | Y | T | N | F |
Template Known Secondary structure |   |
 |  |
| T | T |
|
|  |  |
|
|
| G | G | G | G | S |  |  |  |  |  |  |  |  |  |  | S | T | T |
|
| S |
| S |  |  |  |  |  | S | S |
| T | T |
|  |  |  |
| . | . | . |  |  |  |  |  |  |  |
|
|
| S |  | . | . |  |  |  |  |
| T | T |
| T | T | G | G | G |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |
|
|
|
|  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
265 | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
|
|
. | . | . | . | . | 320 | . | . | . | . | . | . | |
|
. | . | . | 330 | . | . | . | . | . | . | . | . | . |
  |
  |   |
176 | . | . | |
|
|
|
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Y | G | . |
. |
. |
. |
. |
. |
C | E | L | K | E | I | T | Q | Y | C | D | S | F | T | I | C | L | S | K | G | L | G | T | P | V | G | S | L | L | V | . |
. |
. |
. |
. |
G | N | R | D | Y | I | K | R | A | I | R | W | R | K | M | T | G | G | G | M | R | Q | S | G | I | L | A | A | A | G | I | Y | A | L | K | N |
Query Conservation |   |
  |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|
|
|   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|   |
|   |
|
|
|   |   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|   |   |
|   |   |
|
Template Sequence |   |
S | P | I | Y | E | G | K | C | G | M | S | G | G | R | V | E | G | K | V | I | Y | E | T | Q | S | T | H | L | . |
L | A | A | F | S | Q | A | S | M | I | H | V | K | G | D | V | N | E | E | T | F | N | E | A | Y | M | M | H | T | T | T | S | P | H | Y | G | I | V | A | S | T | E | T | A | A | A | M | M | K | G | N |
Template Known Secondary structure |   |
S | G | G | G | T | T | S | S | T | T | S | S |
|
|
| T | T |
|  |  |  |  |  |  |
|
|
|
| . |
| S |
|
| T | T |
|  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  | S |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | |
. | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . |
  |
  |   |
|
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 270 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 280 | . | . | . | |
|
|
Predicted Secondary structure |   |
. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . |
|  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
| . | . | . |
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
. |
N | V | A | R | L | Q | E | D | H | D | N | A | A | W | M | A | E | Q | L | R | E | A | G | . |
. |
. |
. |
. |
. |
. |
A | D | V | M | R | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | T | N | M | L | F | V | R | V | G | . |
. |
. |
Query Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   | . | . | . |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |
|   |   |
|   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|   |
|   |   |
Template Sequence |   |
A | G | K | R | L | I | N | G | S | I | E | R | A | I | K | F | R | K | E | I | K | R | L | R | T | E | S | D | G | W | F | F | D | V | W | Q | P | D | H | I | D | T | T | E | C | W | P | L | R | S | D | S | T | W | H | G | F | K | N | I | D | N | E | H | M | Y | L | D | P | I | K | V | T | L | L | T | P | G | M | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S |
|
|
|  |  | S | S |
| S |
|
|
| S |
| S |
|  |  |
|
| T | T |
|
| T | T |
|
| T | T |
|
| S | S | S |  |  |  |
| T | T |  |  |  |  |  |
| S | S | B |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
E | E | N | A | A | A | L | G | E | Y | M | K | A | R | N | V | L | I | . |
. |
N | A | S | P | I | V | R | L | V | T | H | L | D | V | S | R | E | Q | L | A | E | V | A | A | H | W | R | A | F |
Query Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
| . | . |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
K | D | G | T | M | S | D | F | G | I | P | A | S | I | V | A | K | Y | L | D | E | H | G | I | V | V | E | K | T | G | P | Y | N | L | L | F | L | F | S | I | G | I | D | K | T | K | A | L | S | L | L | R | A | L | T | D | F |
Template Known Secondary structure |   |
S | S | S |
| B |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |  |  |
| S | S |  |  |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . |
  |